SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mg0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		4 / 5 SER C 219
ASP C 218
PRO C 143
SER C  72
 None
 0.92A 2hdnA-3mg0C:
undetectable
2hdnB-3mg0C:
undetectable
2hdnD-3mg0C:
undetectable		 2hdnA-3mg0C:
10.81
2hdnB-3mg0C:
20.00
2hdnD-3mg0C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		4 / 5 SER C  72
SER C 219
ASP C 218
PRO C 143
 None
 0.94A 2hdnB-3mg0C:
undetectable
2hdnC-3mg0C:
undetectable
2hdnD-3mg0C:
undetectable		 2hdnB-3mg0C:
20.00
2hdnC-3mg0C:
10.81
2hdnD-3mg0C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		4 / 7 SER C 219
ASP C 218
PRO C 143
SER C  72
 None
 0.95A 2hdnE-3mg0C:
undetectable
2hdnF-3mg0C:
undetectable
2hdnH-3mg0C:
undetectable		 2hdnE-3mg0C:
10.81
2hdnF-3mg0C:
20.00
2hdnH-3mg0C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		4 / 7 SER C 219
ASP C 218
SER C  72
VAL C  74
 None
 0.78A 2hdnE-3mg0C:
undetectable
2hdnF-3mg0C:
undetectable
2hdnH-3mg0C:
undetectable		 2hdnE-3mg0C:
10.81
2hdnF-3mg0C:
20.00
2hdnH-3mg0C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		4 / 7 SER C  72
SER C 219
ASP C 218
PRO C 143
 None
 0.96A 2hdnF-3mg0C:
undetectable
2hdnG-3mg0C:
undetectable
2hdnH-3mg0C:
undetectable		 2hdnF-3mg0C:
20.00
2hdnG-3mg0C:
10.81
2hdnH-3mg0C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		4 / 7 SER C  72
VAL C  74
SER C 219
ASP C 218
 None
 0.79A 2hdnF-3mg0C:
undetectable
2hdnG-3mg0C:
undetectable
2hdnH-3mg0C:
undetectable		 2hdnF-3mg0C:
20.00
2hdnG-3mg0C:
10.81
2hdnH-3mg0C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		4 / 6 SER C 219
ASP C 218
PRO C 143
SER C  72
 None
 0.93A 2hdnI-3mg0C:
undetectable
2hdnJ-3mg0C:
undetectable
2hdnL-3mg0C:
undetectable		 2hdnI-3mg0C:
10.81
2hdnJ-3mg0C:
20.00
2hdnL-3mg0C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		4 / 6 SER C  72
SER C 219
ASP C 218
PRO C 143
 None
 0.94A 2hdnJ-3mg0C:
undetectable
2hdnK-3mg0C:
undetectable
2hdnL-3mg0C:
undetectable		 2hdnJ-3mg0C:
20.00
2hdnK-3mg0C:
10.81
2hdnL-3mg0C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		4 / 6 SER C  72
VAL C  74
SER C 219
ASP C 218
 None
 0.68A 2hdnJ-3mg0C:
undetectable
2hdnK-3mg0C:
undetectable
2hdnL-3mg0C:
undetectable		 2hdnJ-3mg0C:
20.00
2hdnK-3mg0C:
10.81
2hdnL-3mg0C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		5 / 12 SER C  72
SER C 219
VAL C 107
ALA C  96
GLN C  97
 None
 1.15A 2x2iA-3mg0C:
undetectable		 2x2iA-3mg0C:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		5 / 12 SER C  72
SER C 219
VAL C 107
ALA C  96
GLN C  97
 None
 1.12A 2x2iC-3mg0C:
undetectable		 2x2iC-3mg0C:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		5 / 12 GLY C  39
GLY C  49
VAL C 190
ILE C 165
LEU C 148
 None
 1.01A 3cjtO-3mg0C:
undetectable		 3cjtO-3mg0C:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		5 / 12 LEU C  48
ALA C 139
VAL C 116
THR C 113
VAL C 109
 None
 0.97A 3cwkA-3mg0C:
1.6		 3cwkA-3mg0C:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		5 / 7 LEU C 176
SER C 196
THR C 164
GLY C  49
ILE C 212
 None
 1.21A 4yjiA-3mg0C:
undetectable		 4yjiA-3mg0C:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		5 / 12 ILE C  70
ALA C  92
TYR C 115
LEU C  76
VAL C 116
 None
 1.21A 5hw4A-3mg0C:
undetectable		 5hw4A-3mg0C:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		5 / 12 ILE C  70
ALA C  92
TYR C 115
LEU C  76
VAL C 116
 None
 1.22A 5hw4C-3mg0C:
undetectable		 5hw4C-3mg0C:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3mg0 PROTEASOME COMPONENT
PRE6
(Saccharomyces
cerevisiae) 		5 / 10 GLU C 211
LEU C  28
ALA C  37
THR C 151
LEU C  76
 None
 1.36A 5mm4B-3mg0C:
undetectable		 5mm4B-3mg0C:
18.14