SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mg3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AO8_A_MTXA170_1
(DIHYDROFOLATE
REDUCTASE)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		6 / 12 LEU A  68
PHE A 109
THR A  97
SER A 100
LEU A  86
ALA A  67
 None
 1.27A 1ao8A-3mg3A:
undetectable		 1ao8A-3mg3A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZF_A_TMQA170_1
(DIHYDROFOLATE
REDUCTASE)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A  68
PHE A 109
THR A  97
LEU A  86
ALA A  67
 None
 1.04A 1bzfA-3mg3A:
undetectable		 1bzfA-3mg3A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 TYR A 201
LEU A 205
LEU A 248
ILE A 303
ILE A 214
 ECH  A 351 (-4.5A)
ECH  A 351 (-4.6A)
ECH  A 351 ( 3.8A)
ECH  A 351 (-2.7A)
None
 1.00A 1tw4B-3mg3A:
1.1		 1tw4B-3mg3A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 LEU A 116
GLY A 114
LEU A  68
PRO A  56
 None
ECH  A 351 (-2.8A)
None
GOL  A 324 (-4.1A)
 0.80A 1ya4B-3mg3A:
undetectable		 1ya4B-3mg3A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 PRO A 226
PRO A 103
ILE A 286
VAL A 273
LEU A 250
 GOL  A 326 (-3.8A)
GOL  A 325 ( 3.8A)
ECH  A 351 ( 4.2A)
ECH  A 351 (-4.1A)
ECH  A 351 ( 3.6A)
 1.21A 1z9hD-3mg3A:
undetectable		 1z9hD-3mg3A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ALA A  67
LEU A  94
ALA A  82
VAL A 122
GLN A 119
 None
 1.10A 2ve3A-3mg3A:
undetectable		 2ve3A-3mg3A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 TYR A  98
PHE A 109
GLN A  72
GLY A 108
 None
 0.82A 3hjoA-3mg3A:
undetectable		 3hjoA-3mg3A:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A  40
TRP A  41
ALA A  38
LEU A 131
LEU A  31
 ECH  A 351 (-3.5A)
ECH  A 351 ( 4.7A)
None
None
None
 0.95A 3ix9A-3mg3A:
undetectable		 3ix9A-3mg3A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE A  12
THR A  15
ASP A 304
ILE A  11
 None
 1.08A 3t01A-3mg3A:
undetectable		 3t01A-3mg3A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 PRO A 226
PHE A 240
TRP A 288
TYR A 201
 GOL  A 326 (-3.8A)
ECH  A 351 (-4.0A)
ECH  A 351 (-3.8A)
ECH  A 351 (-4.5A)
 1.31A 4v2zC-3mg3A:
undetectable		 4v2zC-3mg3A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ASP A 209
ASN A 247
GLN A 246
 None
 0.73A 5k7uA-3mg3A:
undetectable		 5k7uA-3mg3A:
21.50