SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3mg9 TEG12
(uncultured
soil
bacterium) 		3 / 3 ALA A  83
VAL A  85
TRP A   6
 None
 0.84A 1bdwA-3mg9A:
undetectable
1bdwB-3mg9A:
undetectable		 1bdwA-3mg9A:
5.81
1bdwB-3mg9A:
5.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3mg9 TEG12
(uncultured
soil
bacterium) 		3 / 3 LEU A 253
TYR A 264
GLN A 265
 None
 0.73A 2wekA-3mg9A:
undetectable		 2wekA-3mg9A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3mg9 TEG12
(uncultured
soil
bacterium) 		4 / 7 PHE A 120
GLU A 124
SER A 141
TRP A 142
 None
 1.27A 3dqtA-3mg9A:
undetectable
3dqtB-3mg9A:
undetectable		 3dqtA-3mg9A:
20.82
3dqtB-3mg9A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 3mg9 TEG12
(uncultured
soil
bacterium) 		3 / 3 GLU A 124
GLY A 273
SER A 141
 None
 0.70A 4b53B-3mg9A:
undetectable		 4b53B-3mg9A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3mg9 TEG12
(uncultured
soil
bacterium) 		4 / 7 PHE A 120
GLU A 124
SER A 141
TRP A 142
 None
 1.36A 4k5jA-3mg9A:
undetectable
4k5jB-3mg9A:
undetectable		 4k5jA-3mg9A:
20.48
4k5jB-3mg9A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 3mg9 TEG12
(uncultured
soil
bacterium) 		5 / 10 LEU A 267
ARG A  93
PRO A  92
GLU A 124
LEU A 253
 None
 1.29A 4la0A-3mg9A:
undetectable		 4la0A-3mg9A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3mg9 TEG12
(uncultured
soil
bacterium) 		4 / 4 ASN A   2
GLY A   3
ASP A 195
ASP A 186
 None
 1.36A 4n49A-3mg9A:
undetectable		 4n49A-3mg9A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3mg9 TEG12
(uncultured
soil
bacterium) 		5 / 12 GLY A 140
GLY A 127
ASN A 123
ASP A  71
ALA A   8
 None
 1.02A 4uckB-3mg9A:
undetectable		 4uckB-3mg9A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3mg9 TEG12
(uncultured
soil
bacterium) 		5 / 12 GLY A  14
SER A  98
THR A  16
VAL A  18
LEU A  88
 None
None
FMT  A 289 ( 4.7A)
None
None
 1.13A 5kocB-3mg9A:
undetectable		 5kocB-3mg9A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3mg9 TEG12
(uncultured
soil
bacterium) 		5 / 9 PHE A 274
SER A 272
GLY A 270
ALA A 284
LEU A 268
 None
 1.49A 5l8rA-3mg9A:
undetectable		 5l8rA-3mg9A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3mg9 TEG12
(uncultured
soil
bacterium) 		4 / 7 SER A 141
TRP A 142
PHE A 120
GLU A 124
 None
 1.26A 6av6A-3mg9A:
undetectable
6av6B-3mg9A:
undetectable		 6av6A-3mg9A:
15.23
6av6B-3mg9A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3mg9 TEG12
(uncultured
soil
bacterium) 		4 / 7 SER A 141
TRP A 142
PHE A 120
GLU A 124
 None
 1.24A 6av7A-3mg9A:
undetectable
6av7B-3mg9A:
undetectable		 6av7A-3mg9A:
15.23
6av7B-3mg9A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3mg9 TEG12
(uncultured
soil
bacterium) 		4 / 5 ARG A 166
MET A 165
THR A 164
LEU A 163
 None
 1.06A 6nknW-3mg9A:
undetectable		 6nknW-3mg9A:
12.50