SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mgf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		4 / 7 GLY A  37
PHE A  71
PRO A  70
TYR A  35
 None
 1.11A 2aouB-3mgfA:
undetectable		 2aouB-3mgfA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		3 / 3 GLU A 147
HIS A 217
HIS A 193
 CFY  A  66 ( 4.8A)
None
None
 0.94A 3co4A-3mgfA:
undetectable		 3co4A-3mgfA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		3 / 3 TYR A 163
MET A 162
ILE A 195
 None
CFY  A  66 ( 3.3A)
None
 0.67A 4c8bB-3mgfA:
undetectable		 4c8bB-3mgfA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		3 / 3 SER A 218
ALA A 216
VAL A 215
 None
 0.60A 4o2bA-3mgfA:
undetectable		 4o2bA-3mgfA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		3 / 3 PRO A 190
MET A 189
TYR A  81
 None
 0.77A 4qa0B-3mgfA:
undetectable		 4qa0B-3mgfA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		3 / 3 PRO A 190
MET A 189
TYR A  81
 None
 0.78A 4qa0A-3mgfA:
undetectable		 4qa0A-3mgfA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		3 / 3 PRO A 190
MET A 189
TYR A  81
 None
 0.84A 4qa2B-3mgfA:
undetectable		 4qa2B-3mgfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		4 / 5 GLY A  32
ARG A  33
GLY A  37
GLU A  36
 None
 1.28A 4z2eB-3mgfA:
undetectable
4z2eC-3mgfA:
undetectable		 4z2eB-3mgfA:
17.89
4z2eC-3mgfA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		5 / 11 ILE A 195
VAL A 160
SER A 145
LEU A 156
THR A 150
 None
None
CFY  A  66 ( 2.4A)
None
None
 1.17A 5tiyA-3mgfA:
undetectable		 5tiyA-3mgfA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		4 / 8 TYR A 163
GLY A 170
ASP A 141
PRO A 144
 None
 0.94A 6ag0C-3mgfA:
undetectable		 6ag0C-3mgfA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 3mgf FLUORESCENT PROTEIN
(Verrillofungia
concinna) 		4 / 8 VAL A 140
HIS A 172
ASN A 171
CYH A 174
 None
 1.13A 6gneB-3mgfA:
undetectable		 6gneB-3mgfA:
17.88