SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mgg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 248
THR A 254
PRO A 150
 None
 0.84A 1a7yA-3mggA:
undetectable		 1a7yA-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 254
PRO A 150
THR A 248
 None
 0.88A 1a7yB-3mggA:
undetectable		 1a7yB-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 248
THR A 254
PRO A 150
 None
 0.84A 1a7yB-3mggA:
undetectable		 1a7yB-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		4 / 8 PHE A 188
THR A 265
ILE A 136
HIS A 106
 None
 0.98A 1ei6D-3mggA:
undetectable		 1ei6D-3mggA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 248
THR A 254
PRO A 150
 None
 0.85A 1i3wF-3mggA:
undetectable		 1i3wF-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 254
PRO A 150
THR A 248
 None
 0.86A 1i3wG-3mggA:
undetectable		 1i3wG-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 248
THR A 254
PRO A 150
 None
 0.84A 1qfiA-3mggA:
undetectable		 1qfiA-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 254
PRO A 150
THR A 248
 None
 0.83A 1unjF-3mggA:
undetectable		 1unjF-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 248
THR A 254
PRO A 150
 None
 0.79A 1unjF-3mggA:
undetectable		 1unjF-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 254
PRO A 150
THR A 248
 None
 0.86A 1unjL-3mggA:
undetectable		 1unjL-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 248
THR A 254
PRO A 150
 None
 0.85A 1unjL-3mggA:
undetectable		 1unjL-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 254
PRO A 150
THR A 248
 None
 0.86A 1unjR-3mggA:
undetectable		 1unjR-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 248
THR A 254
PRO A 150
 None
 0.84A 1unjR-3mggA:
undetectable		 1unjR-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 254
PRO A 150
THR A 248
 None
 0.84A 1unjX-3mggA:
undetectable		 1unjX-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 248
THR A 254
PRO A 150
 None
 0.84A 1unjX-3mggA:
undetectable		 1unjX-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 THR A 254
PRO A 150
THR A 248
 None
 0.87A 1unmF-3mggA:
undetectable		 1unmF-3mggA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 GLY A  43
GLY A  45
ILE A  67
ASN A  93
PHE A 111
 None
 0.67A 2vdvE-3mggA:
12.7		 2vdvE-3mggA:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 11 GLY A  43
GLY A  45
ILE A  67
ASN A  93
PHE A 111
 None
 0.66A 2vdvF-3mggA:
12.7		 2vdvF-3mggA:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 11 GLU A  41
GLY A  43
GLY A  45
ILE A  65
PHE A 111
 None
 0.52A 3dxyA-3mggA:
15.3		 3dxyA-3mggA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 11 GLY A  47
THR A  79
ASN A  86
SER A  64
LEU A  53
 None
 1.40A 3ndvA-3mggA:
undetectable
3ndvB-3mggA:
undetectable		 3ndvA-3mggA:
19.84
3ndvB-3mggA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 11 GLY A  47
THR A  79
ASN A  86
SER A  64
LEU A  53
 None
 1.40A 3ndvC-3mggA:
undetectable
3ndvD-3mggA:
undetectable		 3ndvC-3mggA:
19.84
3ndvD-3mggA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 ILE A  46
GLY A  43
ILE A  67
ILE A  94
LEU A 116
 None
 0.89A 3uj6A-3mggA:
16.7		 3uj6A-3mggA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 GLY A 262
ILE A 136
VAL A 175
LEU A 182
PRO A 181
 None
 1.04A 4gc9A-3mggA:
9.8		 4gc9A-3mggA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 GLY A  43
GLY A  45
ILE A  94
HIS A 115
LEU A 116
 None
 0.88A 4iv0A-3mggA:
16.9		 4iv0A-3mggA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		6 / 12 ILE A  46
GLY A  43
GLY A  45
ILE A  67
ILE A  94
LEU A 116
 None
 1.34A 4iv0A-3mggA:
16.9		 4iv0A-3mggA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		6 / 12 GLY A  43
GLY A  45
ASP A  66
ILE A  67
ILE A  94
LEU A 116
 None
 1.14A 4iv8A-3mggA:
17.0		 4iv8A-3mggA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		6 / 12 GLY A  43
GLY A  45
ASP A  66
ILE A  94
HIS A 115
LEU A 116
 None
 1.05A 4iv8A-3mggA:
17.0		 4iv8A-3mggA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 GLY A  43
GLY A  45
ILE A  94
HIS A 115
LEU A 116
 None
 0.89A 4mwzA-3mggA:
16.9		 4mwzA-3mggA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		6 / 12 ILE A  46
GLY A  43
GLY A  45
ILE A  67
ILE A  94
LEU A 116
 None
 1.27A 4mwzA-3mggA:
16.9		 4mwzA-3mggA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 GLY A  43
GLY A  45
ILE A  94
HIS A 115
LEU A 116
 None
 0.86A 4mwzB-3mggA:
16.7		 4mwzB-3mggA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		6 / 12 ILE A  46
GLY A  43
GLY A  45
ILE A  67
ILE A  94
LEU A 116
 None
 1.35A 4mwzB-3mggA:
16.7		 4mwzB-3mggA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 GLU A  41
GLY A  43
SER A  68
ILE A  94
VAL A 112
 None
 0.61A 5dpdA-3mggA:
14.6		 5dpdA-3mggA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 GLY A  43
ASP A  66
SER A  68
ILE A  94
VAL A 112
 None
 0.62A 5dpdB-3mggA:
4.0		 5dpdB-3mggA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 GLY A  45
ASP A  66
ASN A  93
 None
 0.17A 5jglA-3mggA:
19.8		 5jglA-3mggA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		3 / 3 ASP A  66
ASN A  93
PHE A 111
 None
 0.55A 5jglB-3mggA:
16.7		 5jglB-3mggA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 ILE A  46
GLY A  45
PHE A 111
VAL A 112
ALA A  48
 None
 1.15A 5n0oB-3mggA:
undetectable		 5n0oB-3mggA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		6 / 12 GLY A  43
GLY A  45
ASP A  66
ILE A  67
HIS A 115
LEU A 116
 None
 0.71A 5wy0A-3mggA:
14.1		 5wy0A-3mggA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		6 / 12 LEU A  97
ILE A  65
GLY A  43
LEU A  53
VAL A  39
ILE A 107
 None
 1.20A 5ycnA-3mggA:
undetectable		 5ycnA-3mggA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 LEU A 126
LEU A  97
ALA A  92
LEU A  40
GLY A  45
 None
 0.98A 6b0cD-3mggA:
2.9		 6b0cD-3mggA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 GLY A  43
GLY A  45
ILE A  67
GLU A 114
VAL A 112
 None
 0.97A 6ectA-3mggA:
14.0		 6ectA-3mggA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 GLY A  43
GLY A  45
ILE A  67
GLU A 114
VAL A 112
 None
 0.99A 6ecxA-3mggA:
13.9		 6ecxA-3mggA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 3mgg METHYLTRANSFERASE
(Methanosarcina
mazei) 		5 / 12 GLU A  41
GLY A  43
GLY A  45
ALA A  48
ILE A  67
 None
 0.83A 6iftA-3mggA:
11.2		 6iftA-3mggA:
23.92