SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mgl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 10 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.83A 1hsgA-3mglA:
undetectable		 1hsgA-3mglA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.74A 1hxbB-3mglA:
undetectable		 1hxbB-3mglA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A 487
LEU A 477
MET A 483
ILE A 488
LEU A 518
 None
 0.85A 1lhuA-3mglA:
undetectable		 1lhuA-3mglA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 9 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.88A 1ohrB-3mglA:
undetectable		 1ohrB-3mglA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		3 / 3 LEU A 506
HIS A 499
ILE A 495
 None
 0.69A 1s9pB-3mglA:
undetectable		 1s9pB-3mglA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.69A 1t3rB-3mglA:
undetectable		 1t3rB-3mglA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.92A 2f8gB-3mglA:
undetectable		 2f8gB-3mglA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.90A 2ienB-3mglA:
undetectable		 2ienB-3mglA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 9 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.78A 2o4pB-3mglA:
undetectable		 2o4pB-3mglA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.76A 2q64B-3mglA:
undetectable		 2q64B-3mglA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		6 / 12 GLY A 538
ALA A 539
ILE A 507
GLY A 509
VAL A 444
ILE A 474
 IOD  A 604 ( 3.7A)
None
None
IOD  A 602 ( 3.7A)
None
None
 1.01A 2r5pB-3mglA:
undetectable		 2r5pB-3mglA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		6 / 12 GLY A 538
ALA A 539
ILE A 507
GLY A 509
VAL A 444
ILE A 474
 IOD  A 604 ( 3.7A)
None
None
IOD  A 602 ( 3.7A)
None
None
 1.00A 2r5pD-3mglA:
undetectable		 2r5pD-3mglA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.75A 3bvbA-3mglA:
undetectable		 3bvbA-3mglA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.80A 3bvbB-3mglA:
undetectable		 3bvbB-3mglA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 10 GLY A 538
ALA A 539
GLY A 509
VAL A 444
ILE A 474
 IOD  A 604 ( 3.7A)
None
IOD  A 602 ( 3.7A)
None
None
 0.91A 3ekyA-3mglA:
undetectable		 3ekyA-3mglA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 10 GLY A 538
ALA A 539
GLY A 509
VAL A 444
ILE A 474
 IOD  A 604 ( 3.7A)
None
IOD  A 602 ( 3.7A)
None
None
 0.88A 3em3A-3mglA:
undetectable		 3em3A-3mglA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 10 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.88A 3em3A-3mglA:
undetectable		 3em3A-3mglA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.76A 3em6B-3mglA:
undetectable		 3em6B-3mglA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.78A 3jvyA-3mglA:
undetectable		 3jvyA-3mglA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.78A 3jw2A-3mglA:
undetectable		 3jw2A-3mglA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.74A 3k4vB-3mglA:
undetectable		 3k4vB-3mglA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.84A 3lzuB-3mglA:
undetectable		 3lzuB-3mglA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.86A 3ndtD-3mglA:
undetectable		 3ndtD-3mglA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 10 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.85A 3oxwD-3mglA:
undetectable		 3oxwD-3mglA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.78A 3oy4A-3mglA:
undetectable		 3oy4A-3mglA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.79A 3tkwB-3mglA:
undetectable		 3tkwB-3mglA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.73A 4dqbA-3mglA:
undetectable		 4dqbA-3mglA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.76A 4dqeA-3mglA:
undetectable		 4dqeA-3mglA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.79A 4dqfA-3mglA:
undetectable		 4dqfA-3mglA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.68A 4dqhA-3mglA:
undetectable		 4dqhA-3mglA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		3 / 3 VAL A 519
GLY A 522
LYS A 525
 None
 0.77A 4k50A-3mglA:
undetectable		 4k50A-3mglA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		3 / 3 VAL A 519
GLY A 522
LYS A 525
 None
 0.75A 4k50E-3mglA:
undetectable		 4k50E-3mglA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.97A 4qgiB-3mglA:
undetectable		 4qgiB-3mglA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 7 SER A 497
ILE A 495
LEU A 473
PHE A 498
 None
 0.90A 4uymA-3mglA:
undetectable		 4uymA-3mglA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_1
(PROTEASE E35D-DRV)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.74A 5kqyA-3mglA:
undetectable		 5kqyA-3mglA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 PHE A 536
SER A 508
ILE A 472
ALA A 543
LEU A 540
 None
IOD  A 602 (-3.4A)
None
None
None
 1.22A 5oy02-3mglA:
undetectable		 5oy02-3mglA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 7 LEU A 475
LEU A 447
ALA A 455
ALA A 456
 None
 0.81A 6a7jA-3mglA:
undetectable		 6a7jA-3mglA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 3mgl SULFATE PERMEASE
FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 475
VAL A 532
GLY A 522
VAL A 505
ILE A 507
 None
 0.80A 6dgxB-3mglA:
undetectable		 6dgxB-3mglA:
21.60