SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mgw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3mgw LYSOZYME G
(Salmo
salar) 		4 / 8 ILE A 127
ILE A 124
VAL A 154
ILE A 144
 None
 0.88A 3p4wC-3mgwA:
undetectable		 3p4wC-3mgwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_B_VIBB187_1
(THIT)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 12 ILE A  69
GLU A  73
TYR A 169
GLY A  15
VAL A 174
 None
 1.49A 3rlbB-3mgwA:
undetectable		 3rlbB-3mgwA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 12 ASP A  86
HIS A 112
GLY A  90
GLY A 116
TYR A 147
 None
 1.21A 4lxzA-3mgwA:
undetectable		 4lxzA-3mgwA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 12 ASP A  86
HIS A 112
GLY A  90
GLY A 116
TYR A 147
 None
 1.22A 4lxzC-3mgwA:
undetectable		 4lxzC-3mgwA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 12 LEU A 140
GLY A 143
LEU A  61
GLN A 178
THR A  13
 None
 1.46A 4p6xE-3mgwA:
undetectable		 4p6xE-3mgwA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 12 GLY A  60
GLY A 116
GLY A  56
VAL A  96
ILE A 119
 None
 0.91A 5ehgC-3mgwA:
undetectable		 5ehgC-3mgwA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3mgw LYSOZYME G
(Salmo
salar) 		4 / 6 GLY A  15
THR A  13
SER A  34
VAL A  31
 None
 0.86A 5ewuA-3mgwA:
undetectable		 5ewuA-3mgwA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 12 GLY A  60
GLY A 116
GLY A  56
VAL A  96
ILE A 119
 None
 0.94A 5kqrA-3mgwA:
undetectable		 5kqrA-3mgwA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 12 GLY A  60
GLY A 116
GLY A  56
VAL A  96
ILE A 119
 None
 0.93A 5kqsA-3mgwA:
undetectable		 5kqsA-3mgwA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 12 GLY A  60
GLY A 116
GLY A  56
VAL A  96
ILE A 119
 None
 0.92A 5m5bA-3mgwA:
undetectable		 5m5bA-3mgwA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 10 ILE A 121
ILE A 124
ILE A  65
ILE A  66
ILE A  69
 None
 0.64A 5murE-3mgwA:
undetectable		 5murE-3mgwA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 10 ILE A  69
ILE A  70
MET A  94
TYR A 185
ILE A  52
 None
 1.41A 5mzrA-3mgwA:
undetectable		 5mzrA-3mgwA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 10 ILE A  69
ILE A  70
MET A  94
TYR A 185
ILE A  52
 None
 1.39A 5mzrC-3mgwA:
undetectable		 5mzrC-3mgwA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 9 ILE A  69
ILE A  70
MET A  94
TYR A 185
ILE A  52
 None
 1.40A 5mzrD-3mgwA:
undetectable		 5mzrD-3mgwA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3mgw LYSOZYME G
(Salmo
salar) 		5 / 12 GLY A  60
GLY A 116
GLY A  56
VAL A  96
ILE A 119
 None
 0.92A 5vimB-3mgwA:
undetectable		 5vimB-3mgwA:
20.68