SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mha'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 114
PRO A 117
THR A 116
 None
 0.88A 1a7yB-3mhaA:
undetectable		 1a7yB-3mhaA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 114
PRO A 117
THR A 116
 None
 0.85A 1mnvD-3mhaA:
undetectable		 1mnvD-3mhaA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 114
PRO A 117
THR A 116
 None
 0.82A 1unjF-3mhaA:
undetectable		 1unjF-3mhaA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 116
THR A 114
PRO A 117
 None
 0.85A 1unjF-3mhaA:
undetectable		 1unjF-3mhaA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 114
PRO A 117
THR A 116
 None
 0.88A 1unjL-3mhaA:
undetectable		 1unjL-3mhaA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 116
THR A 114
PRO A 117
 None
 0.86A 1unjL-3mhaA:
undetectable		 1unjL-3mhaA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 114
PRO A 117
THR A 116
 None
 0.82A 1unjR-3mhaA:
undetectable		 1unjR-3mhaA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 116
THR A 114
PRO A 117
 None
 0.83A 1unjR-3mhaA:
undetectable		 1unjR-3mhaA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 114
PRO A 117
THR A 116
 None
 0.84A 1unjX-3mhaA:
undetectable		 1unjX-3mhaA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 116
THR A 114
PRO A 117
 None
 0.85A 1unjX-3mhaA:
undetectable		 1unjX-3mhaA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  80
PHE A 104
ALA A 126
VAL A  91
GLY A  78
 Z69  A   1 ( 4.6A)
Z69  A   1 (-4.1A)
None
Z69  A   1 (-4.8A)
None
 1.11A 3c6gB-3mhaA:
undetectable		 3c6gB-3mhaA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		5 / 10 THR A 193
GLY A 212
GLY A 170
ALA A 192
LYS A 171
 None
 1.28A 3pp7B-3mhaA:
undetectable		 3pp7B-3mhaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		4 / 6 VAL A  61
HIS A  59
SER A 222
THR A 220
 None
 1.07A 3tj7C-3mhaA:
undetectable
3tj7D-3mhaA:
1.9		 3tj7C-3mhaA:
23.31
3tj7D-3mhaA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		4 / 4 PRO A  43
LEU A  44
ILE A 166
ARG A 157
 None
 1.32A 4f4dA-3mhaA:
undetectable		 4f4dA-3mhaA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 111
THR A 116
ALA A 102
VAL A  91
ILE A 100
 Z69  A   1 ( 4.8A)
None
Z69  A   1 ( 4.9A)
Z69  A   1 (-4.8A)
None
 1.00A 4x1kD-3mhaA:
undetectable		 4x1kD-3mhaA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 111
THR A 116
ALA A 102
VAL A  91
ILE A 100
 Z69  A   1 ( 4.8A)
None
Z69  A   1 ( 4.9A)
Z69  A   1 (-4.8A)
None
 0.97A 4x20D-3mhaA:
undetectable		 4x20D-3mhaA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		3 / 3 THR A 220
MET A  60
HIS A  59
 None
Z69  A   1 (-3.0A)
None
 0.89A 5uunA-3mhaA:
undetectable		 5uunA-3mhaA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		4 / 5 MET A 219
ASN A 215
VAL A  64
LEU A  62
 Z69  A   1 (-4.2A)
None
None
Z69  A   1 ( 4.8A)
 1.32A 5xdhB-3mhaA:
undetectable		 5xdhB-3mhaA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		4 / 5 MET A 219
ASN A 215
VAL A  64
LEU A  62
 Z69  A   1 (-4.2A)
None
None
Z69  A   1 ( 4.8A)
 1.15A 5xdhD-3mhaA:
undetectable		 5xdhD-3mhaA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		5 / 10 ILE A 180
ILE A 160
ALA A 205
LEU A 204
ALA A  48
 Z69  A   1 (-4.4A)
None
None
None
None
 0.98A 5zjiB-3mhaA:
undetectable		 5zjiB-3mhaA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3mha LIPOPROTEIN LPRG
(Mycobacterium
tuberculosis) 		5 / 11 THR A  49
VAL A 217
LEU A 209
ALA A 147
VAL A 135
 None
 1.28A 6dryA-3mhaA:
undetectable		 6dryA-3mhaA:
19.90