SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mhp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		5 / 12 LEU A 194
GLY A 167
CYH A 108
ALA A 169
ALA A  92
 None
None
None
FAD  A 999 ( 4.0A)
None
 1.07A 2br4A-3mhpA:
2.7		 2br4A-3mhpA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		5 / 12 LEU A 194
GLY A 167
CYH A 108
ALA A 169
ALA A  92
 None
None
None
FAD  A 999 ( 4.0A)
None
 1.16A 2br4D-3mhpA:
3.6		 2br4D-3mhpA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		3 / 3 LYS A  16
TYR A 264
PRO A 152
 None
 1.29A 2j9cC-3mhpA:
undetectable		 2j9cC-3mhpA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		5 / 9 LEU A 205
ILE A 168
GLY A 167
GLY A 267
SER A 203
 None
 1.11A 2qmmA-3mhpA:
3.9		 2qmmA-3mhpA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		4 / 5 SER A  57
ARG A  35
PRO A 135
GLY A 136
 None
 1.29A 2y7kB-3mhpA:
0.6		 2y7kB-3mhpA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		4 / 6 SER A  57
ARG A  35
PRO A 135
GLY A 136
 None
 1.19A 2y7pA-3mhpA:
undetectable		 2y7pA-3mhpA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		5 / 12 GLY A  34
ILE A 141
TYR A  64
ALA A  92
SER A 106
 None
 1.00A 3hs6B-3mhpA:
undetectable		 3hs6B-3mhpA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		4 / 8 TYR A 186
GLU A  19
SER A 173
ILE A  91
 None
 0.98A 3jz0B-3mhpA:
undetectable		 3jz0B-3mhpA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		5 / 10 VAL A 105
ILE A 141
GLY A 143
VAL A  23
ILE A  91
 None
 1.05A 3oxvB-3mhpA:
undetectable		 3oxvB-3mhpA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		5 / 11 VAL A 105
ILE A 141
GLY A 143
VAL A  23
ILE A  91
 None
 0.99A 3oxvD-3mhpA:
undetectable		 3oxvD-3mhpA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		5 / 10 VAL A 105
ILE A 141
GLY A 143
VAL A  23
ILE A  91
 None
 1.02A 3oxwB-3mhpA:
undetectable		 3oxwB-3mhpA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		5 / 10 ILE A 241
ILE A 168
GLY A 167
GLY A 267
PHE A 225
 None
 0.84A 4fakA-3mhpA:
undetectable		 4fakA-3mhpA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		3 / 3 ARG A  65
GLN A  17
GLU A  19
 None
 0.77A 4tvtA-3mhpA:
undetectable		 4tvtA-3mhpA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAC_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		5 / 12 ASP A  78
HIS A  84
ARG A  87
SER A 127
LEU A 112
 None
None
FAD  A 999 (-3.9A)
FAD  A 999 (-2.7A)
FAD  A 999 (-4.4A)
 1.27A 5uacC-3mhpA:
0.1		 5uacC-3mhpA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		3 / 3 GLU A 208
TYR A 206
ARG A 172
 None
 0.82A 5uunA-3mhpA:
undetectable		 5uunA-3mhpA:
21.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		8 / 9 SER A  90
THR A 166
GLY A 167
ALA A 169
CYH A 266
GLY A 267
LEU A 268
GLU A 306
 FAD  A 999 (-3.4A)
FAD  A 999 (-3.3A)
None
FAD  A 999 ( 4.0A)
None
None
None
FAD  A 999 (-3.6A)
 0.71A 5vw4A-3mhpA:
42.0		 5vw4A-3mhpA:
46.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		7 / 8 SER A  90
THR A 166
GLY A 167
CYH A 266
GLY A 267
LEU A 268
GLU A 306
 FAD  A 999 (-3.4A)
FAD  A 999 (-3.3A)
None
None
None
None
FAD  A 999 (-3.6A)
 0.71A 5vw5A-3mhpA:
41.7		 5vw5A-3mhpA:
46.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		7 / 8 SER A  90
THR A 166
GLY A 167
ALA A 169
CYH A 266
GLY A 267
GLU A 306
 FAD  A 999 (-3.4A)
FAD  A 999 (-3.3A)
None
FAD  A 999 ( 4.0A)
None
None
FAD  A 999 (-3.6A)
 0.58A 5vw9A-3mhpA:
41.8		 5vw9A-3mhpA:
46.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 3mhp FERREDOXIN--NADP
REDUCTASE, LEAF
ISOZYME,
CHLOROPLASTIC
(Pisum
sativum) 		4 / 6 ILE A  91
TYR A  64
ARG A 172
SER A 173
 None
 1.24A 6f6jA-3mhpA:
undetectable		 6f6jA-3mhpA:
undetectable