SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mi6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 GLY A  37
THR A  16
HIS A  18
THR A  19
 None
 0.92A 1c9sT-3mi6A:
undetectable
1c9sU-3mi6A:
undetectable		 1c9sT-3mi6A:
6.47
1c9sU-3mi6A:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		5 / 12 SER A 181
LEU A 120
GLY A 275
TYR A 509
SER A 255
 None
 1.36A 1fdsA-3mi6A:
undetectable		 1fdsA-3mi6A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 5 PHE A 342
GLY A 369
SER A 380
THR A 379
 None
 1.32A 1icuC-3mi6A:
undetectable
1icuD-3mi6A:
undetectable		 1icuC-3mi6A:
15.51
1icuD-3mi6A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 5 PHE A 342
GLY A 369
SER A 380
THR A 379
 None
 1.29A 1icvA-3mi6A:
undetectable
1icvB-3mi6A:
undetectable		 1icvA-3mi6A:
15.51
1icvB-3mi6A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		5 / 12 PHE A  90
LEU A 180
ALA A 179
PHE A 291
LEU A 103
 None
 1.24A 1og5A-3mi6A:
undetectable		 1og5A-3mi6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 4 LEU A 120
GLY A 256
ASP A 535
TYR A 509
 None
 1.37A 1oxrA-3mi6A:
undetectable		 1oxrA-3mi6A:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 TYR A 504
GLU A 416
PRO A 415
VAL A 456
 None
 1.40A 1q13A-3mi6A:
9.7		 1q13A-3mi6A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 TYR A 504
GLU A 416
PRO A 415
VAL A 457
 None
 1.37A 1q13A-3mi6A:
9.7		 1q13A-3mi6A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 4 LEU A 449
VAL A 448
ILE A 433
TRP A 431
 None
 1.16A 1s9qB-3mi6A:
undetectable		 1s9qB-3mi6A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_1
(ORPHAN NUCLEAR
RECEPTOR PXR)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		5 / 12 LEU A 206
SER A 564
GLN A 310
ILE A 194
PHE A 196
 None
 1.23A 1skxA-3mi6A:
undetectable		 1skxA-3mi6A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.28A 1v54A-3mi6A:
undetectable
1v54C-3mi6A:
undetectable		 1v54A-3mi6A:
21.28
1v54C-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.28A 1v54N-3mi6A:
undetectable
1v54P-3mi6A:
undetectable		 1v54N-3mi6A:
21.28
1v54P-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.31A 1v55A-3mi6A:
undetectable
1v55C-3mi6A:
undetectable		 1v55A-3mi6A:
21.28
1v55C-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		3 / 3 PHE A 250
TYR A  36
TYR A 300
 None
 0.96A 1x70B-3mi6A:
undetectable		 1x70B-3mi6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZWP_A_NIMA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 5 LEU A 349
GLY A 369
TRP A 370
ASP A 375
 None
 1.49A 1zwpA-3mi6A:
0.0		 1zwpA-3mi6A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.29A 2dyrA-3mi6A:
undetectable
2dyrC-3mi6A:
undetectable		 2dyrA-3mi6A:
21.28
2dyrC-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.29A 2dyrN-3mi6A:
undetectable
2dyrP-3mi6A:
undetectable		 2dyrN-3mi6A:
21.28
2dyrP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.30A 2dysN-3mi6A:
undetectable
2dysP-3mi6A:
undetectable		 2dysN-3mi6A:
21.28
2dysP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.34A 2eijA-3mi6A:
undetectable
2eijC-3mi6A:
undetectable		 2eijA-3mi6A:
21.28
2eijC-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.31A 2eijN-3mi6A:
undetectable
2eijP-3mi6A:
undetectable		 2eijN-3mi6A:
21.28
2eijP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.33A 2eikA-3mi6A:
undetectable
2eikC-3mi6A:
undetectable		 2eikA-3mi6A:
21.28
2eikC-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.30A 2eikN-3mi6A:
undetectable
2eikP-3mi6A:
undetectable		 2eikN-3mi6A:
21.28
2eikP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.31A 2eilA-3mi6A:
undetectable
2eilC-3mi6A:
undetectable		 2eilA-3mi6A:
21.28
2eilC-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.30A 2eilN-3mi6A:
undetectable
2eilP-3mi6A:
undetectable		 2eilN-3mi6A:
21.28
2eilP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.34A 2eimA-3mi6A:
undetectable
2eimC-3mi6A:
undetectable		 2eimA-3mi6A:
21.28
2eimC-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.31A 2eimN-3mi6A:
undetectable
2eimP-3mi6A:
undetectable		 2eimN-3mi6A:
21.28
2eimP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.24A 2einA-3mi6A:
undetectable
2einC-3mi6A:
undetectable		 2einA-3mi6A:
21.28
2einC-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.28A 2einN-3mi6A:
undetectable
2einP-3mi6A:
undetectable		 2einN-3mi6A:
21.28
2einP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		5 / 12 THR A 551
LEU A 602
ILE A 334
ALA A 578
VAL A 619
 None
 1.17A 2g72B-3mi6A:
undetectable		 2g72B-3mi6A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		5 / 12 LEU A 184
ILE A 272
ALA A 236
LEU A 308
ILE A 194
 None
 1.02A 2h42C-3mi6A:
undetectable		 2h42C-3mi6A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 LEU A 460
MET A 464
LEU A 515
GLU A 416
 None
 1.15A 2kuhA-3mi6A:
undetectable		 2kuhA-3mi6A:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.31A 2y69A-3mi6A:
undetectable
2y69C-3mi6A:
undetectable		 2y69A-3mi6A:
21.28
2y69C-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.30A 2zxwA-3mi6A:
undetectable
2zxwC-3mi6A:
undetectable		 2zxwA-3mi6A:
21.28
2zxwC-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.30A 2zxwN-3mi6A:
undetectable
2zxwP-3mi6A:
undetectable		 2zxwN-3mi6A:
21.28
2zxwP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.33A 3abkN-3mi6A:
undetectable
3abkP-3mi6A:
undetectable		 3abkN-3mi6A:
21.28
3abkP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.26A 3abmN-3mi6A:
undetectable
3abmP-3mi6A:
undetectable		 3abmN-3mi6A:
21.28
3abmP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.26A 3ag1N-3mi6A:
undetectable
3ag1P-3mi6A:
undetectable		 3ag1N-3mi6A:
21.28
3ag1P-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.30A 3ag2N-3mi6A:
undetectable
3ag2P-3mi6A:
undetectable		 3ag2N-3mi6A:
21.28
3ag2P-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.30A 3ag4N-3mi6A:
undetectable
3ag4P-3mi6A:
undetectable		 3ag4N-3mi6A:
21.28
3ag4P-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.31A 3asnA-3mi6A:
undetectable
3asnC-3mi6A:
undetectable		 3asnA-3mi6A:
21.28
3asnC-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 8 ILE A 297
TYR A 567
PRO A 568
GLY A 537
 None
 0.95A 3em0B-3mi6A:
1.9		 3em0B-3mi6A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ALA A 339
ILE A 352
GLU A 605
ALA A 578
 None
 0.87A 3r9sA-3mi6A:
undetectable		 3r9sA-3mi6A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		5 / 9 LEU A  14
ASP A 130
GLY A 113
ILE A 160
ILE A 153
 None
 1.09A 3s56B-3mi6A:
undetectable		 3s56B-3mi6A:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		5 / 12 GLY A 603
ILE A 665
GLY A 600
ALA A 597
ALA A 595
 None
 1.09A 3sudB-3mi6A:
undetectable		 3sudB-3mi6A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		5 / 9 LEU A 184
ILE A  73
ILE A  34
PRO A 187
LEU A 186
 None
 1.05A 3u7sA-3mi6A:
undetectable		 3u7sA-3mi6A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		5 / 12 GLY A 711
LEU A 687
GLY A 704
TYR A 693
PHE A 682
 None
 0.96A 3vywC-3mi6A:
undetectable		 3vywC-3mi6A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 474
GLY A 410
VAL A 522
HIS A 403
 None
 0.81A 4c5nA-3mi6A:
2.4		 4c5nA-3mi6A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ALA A 286
ASN A 284
LEU A 285
VAL A 175
 None
 0.95A 4g24A-3mi6A:
undetectable		 4g24A-3mi6A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASN A 230
ASP A 260
GLY A 249
THR A 563
 None
 1.00A 4l1aB-3mi6A:
undetectable		 4l1aB-3mi6A:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 8 ILE A 476
VAL A 457
LEU A 460
PHE A 413
 None
 0.59A 4r38A-3mi6A:
undetectable		 4r38A-3mi6A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.28A 5b1aN-3mi6A:
undetectable
5b1aP-3mi6A:
undetectable		 5b1aN-3mi6A:
21.28
5b1aP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.30A 5b1bN-3mi6A:
undetectable
5b1bP-3mi6A:
undetectable		 5b1bN-3mi6A:
21.28
5b1bP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.27A 5b3sN-3mi6A:
undetectable
5b3sP-3mi6A:
undetectable		 5b3sN-3mi6A:
21.28
5b3sP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 8 GLY A  37
THR A  16
HIS A  18
THR A  19
 None
 0.93A 5eevL-3mi6A:
undetectable
5eevV-3mi6A:
undetectable		 5eevL-3mi6A:
6.47
5eevV-3mi6A:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 8 GLY A  37
THR A  16
HIS A  18
THR A  19
 None
 0.93A 5eewL-3mi6A:
undetectable
5eewV-3mi6A:
undetectable		 5eewL-3mi6A:
6.47
5eewV-3mi6A:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 8 GLY A  37
THR A  16
HIS A  18
THR A  19
 None
 0.93A 5ef3L-3mi6A:
undetectable
5ef3V-3mi6A:
undetectable		 5ef3L-3mi6A:
6.47
5ef3V-3mi6A:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.26A 5iy5A-3mi6A:
undetectable
5iy5C-3mi6A:
undetectable		 5iy5A-3mi6A:
21.28
5iy5C-3mi6A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ARG A 204
GLN A 560
ILE A 559
GLY A 562
 None
 0.93A 5nzyA-3mi6A:
undetectable		 5nzyA-3mi6A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 8 SER A 653
PHE A 732
GLN A 730
THR A 680
 None
 1.37A 5u6nA-3mi6A:
2.7		 5u6nA-3mi6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 SER A 653
PHE A 732
GLN A 730
THR A 680
 None
 1.33A 5u6nB-3mi6A:
undetectable		 5u6nB-3mi6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.22A 5w97C-3mi6A:
undetectable
5w97a-3mi6A:
undetectable
5w97c-3mi6A:
undetectable		 5w97C-3mi6A:
15.95
5w97a-3mi6A:
21.28
5w97c-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.25A 5x19N-3mi6A:
undetectable
5x19P-3mi6A:
undetectable		 5x19N-3mi6A:
21.28
5x19P-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.27A 5x1bN-3mi6A:
undetectable
5x1bP-3mi6A:
undetectable		 5x1bN-3mi6A:
21.28
5x1bP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.25A 5x1fN-3mi6A:
undetectable
5x1fP-3mi6A:
undetectable		 5x1fN-3mi6A:
21.28
5x1fP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.28A 5zcqN-3mi6A:
undetectable
5zcqP-3mi6A:
undetectable		 5zcqN-3mi6A:
21.28
5zcqP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		3 / 3 ASP A 375
ARG A 389
ASP A 421
 None
 0.84A 5zvgA-3mi6A:
undetectable		 5zvgA-3mi6A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 THR A 340
ARG A 374
HIS A 373
ASP A 368
 None
 1.36A 6mn4E-3mi6A:
undetectable		 6mn4E-3mi6A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ARG A 374
HIS A 373
ASP A 368
GLU A 414
 None
 1.38A 6mn4F-3mi6A:
undetectable		 6mn4F-3mi6A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 GLY A 537
ASN A 230
GLU A 203
GLY A 531
 None
 0.90A 6n7fA-3mi6A:
undetectable		 6n7fA-3mi6A:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.26A 6nknA-3mi6A:
undetectable
6nknC-3mi6A:
undetectable		 6nknA-3mi6A:
21.28
6nknC-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.25A 6nmfN-3mi6A:
undetectable
6nmfP-3mi6A:
undetectable		 6nmfN-3mi6A:
21.28
6nmfP-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 6 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.25A 6nmpA-3mi6A:
undetectable
6nmpC-3mi6A:
undetectable		 6nmpA-3mi6A:
21.28
6nmpC-3mi6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mi6 ALPHA-GALACTOSIDASE
(Lactobacillus
brevis) 		4 / 7 ASP A 642
THR A 652
TYR A 669
HIS A 205
 None
 1.22A 6nmpN-3mi6A:
undetectable
6nmpP-3mi6A:
undetectable		 6nmpN-3mi6A:
21.28
6nmpP-3mi6A:
15.95