SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mi9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3mi9 PROTEIN TAT
(Human
immunodeficiency
virus
1) 		4 / 6 CYH C  34
VAL C  36
HIS C  33
CYH C  22
 ZN  C  87 (-2.3A)
None
ZN  C  87 (-3.3A)
ZN  C  87 (-2.3A)
 1.27A 1ekjG-3mi9C:
undetectable
1ekjH-3mi9C:
undetectable		 1ekjG-3mi9C:
15.94
1ekjH-3mi9C:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 10 VAL A  79
PHE A  59
VAL A  50
ILE A  82
LEU A  70
 None
 1.21A 1fe2A-3mi9A:
undetectable		 1fe2A-3mi9A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 VAL A  33
ALA A  46
GLU A  66
VAL A  79
PHE A 105
LEU A 156
ALA A 166
 None
 0.64A 1opjA-3mi9A:
22.6		 1opjA-3mi9A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
VAL A  79
PHE A 105
ALA A 166
 None
 0.70A 1opjB-3mi9A:
22.3		 1opjB-3mi9A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 ASP A 109
GLY A 112
ALA A 111
ILE A 218
ALA A 166
 None
 1.04A 1sguB-3mi9A:
undetectable		 1sguB-3mi9A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 GLY A 112
ALA A 111
ILE A 218
ILE A 157
ALA A 166
 None
 1.03A 1sguB-3mi9A:
undetectable		 1sguB-3mi9A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 ALA A  46
GLU A  66
LEU A  70
CYH A 106
HIS A 147
 None
 0.50A 1uwhA-3mi9A:
14.5		 1uwhA-3mi9A:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 ALA A  46
LYS A  48
GLU A  66
LEU A  70
CYH A 106
HIS A 147
 None
 0.61A 1uwhB-3mi9A:
14.4		 1uwhB-3mi9A:
26.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EUF_B_LQQB401_1
(CELL DIVISION
PROTEIN KINASE 6)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		10 / 12 ILE A  25
VAL A  33
LYS A  48
VAL A  79
PHE A 103
ASP A 109
ASN A 154
LEU A 156
ALA A 166
ASP A 167
 None
 0.81A 2eufB-3mi9A:
31.7		 2eufB-3mi9A:
37.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_A_MIXA539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 VAL A  33
ALA A  46
ASP A 149
LYS A 151
ALA A 153
ASN A 154
ASP A 167
 None
 0.84A 2fumA-3mi9A:
24.5		 2fumA-3mi9A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
PHE A 105
LEU A 156
ALA A 166
 None
 0.82A 2hyyA-3mi9A:
22.4		 2hyyA-3mi9A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
PHE A 105
LEU A 156
ALA A 166
 None
 0.70A 2hyyB-3mi9A:
22.4		 2hyyB-3mi9A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 VAL A  33
ALA A  46
GLU A  66
VAL A  79
PHE A 105
LEU A 156
ALA A 166
 None
 0.65A 2hyyC-3mi9A:
16.2		 2hyyC-3mi9A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
PHE A 105
LEU A 156
ALA A 166
 None
 0.76A 2hyyD-3mi9A:
22.2		 2hyyD-3mi9A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
ILE A  69
PHE A 105
LEU A 156
ALA A 166
 None
 1.08A 2hyyD-3mi9A:
22.2		 2hyyD-3mi9A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 3mi9 PROTEIN TAT
(Human
immunodeficiency
virus
1) 		3 / 3 CYH C  22
CYH C  34
HIS C  33
 ZN  C  87 (-2.3A)
ZN  C  87 (-2.3A)
ZN  C  87 (-3.3A)
 0.83A 2iwkA-3mi9C:
undetectable		 2iwkA-3mi9C:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 8 LEU A 137
LEU A 212
ASP A 305
ASP A 307
 None
 0.91A 2j2pA-3mi9A:
undetectable
2j2pB-3mi9A:
undetectable		 2j2pA-3mi9A:
17.87
2j2pB-3mi9A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 9 LEU A 137
SER A 306
LEU A 212
ASP A 305
ASP A 307
 None
 1.46A 2j2pB-3mi9A:
undetectable
2j2pC-3mi9A:
undetectable		 2j2pB-3mi9A:
17.87
2j2pC-3mi9A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 7 MET A 150
ILE A 140
PRO A 196
GLY A 207
 None
 0.97A 2pnjB-3mi9A:
undetectable		 2pnjB-3mi9A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 7 LEU A 212
ASP A 211
LEU A 146
ILE A 140
 None
 1.07A 2qqdA-3mi9A:
undetectable
2qqdE-3mi9A:
undetectable		 2qqdA-3mi9A:
13.01
2qqdE-3mi9A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 6 PHE A 168
LEU A 137
PRO A 208
LEU A 146
ALA A 171
 None
 1.41A 2vcvB-3mi9A:
undetectable		 2vcvB-3mi9A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 6 PHE A 168
LEU A 137
PRO A 208
LEU A 146
ALA A 171
 None
 1.26A 2vcvK-3mi9A:
undetectable		 2vcvK-3mi9A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C7Q_A_XINA1172_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 ALA A  46
LYS A  48
VAL A  79
PHE A 105
CYH A 106
LEU A 156
 None
 0.59A 3c7qA-3mi9A:
10.0		 3c7qA-3mi9A:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 3mi9 PROTEIN TAT
(Human
immunodeficiency
virus
1) 		3 / 3 CYH C  31
PHE C  38
PHE C  32
 None
 0.66A 3cr5X-3mi9C:
undetectable		 3cr5X-3mi9C:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3mi9 PROTEIN TAT
(Human
immunodeficiency
virus
1) 		3 / 3 CYH C  22
CYH C  34
HIS C  33
 ZN  C  87 (-2.3A)
ZN  C  87 (-2.3A)
ZN  C  87 (-3.3A)
 0.80A 3dtuB-3mi9C:
undetectable		 3dtuB-3mi9C:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3mi9 PROTEIN TAT
(Human
immunodeficiency
virus
1) 		3 / 3 CYH C  22
CYH C  34
HIS C  33
 ZN  C  87 (-2.3A)
ZN  C  87 (-2.3A)
ZN  C  87 (-3.3A)
 0.77A 3dtuD-3mi9C:
undetectable		 3dtuD-3mi9C:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 ASP A 104
ILE A 140
GLY A 136
HIS A  75
ASN A  80
LEU A  70
 None
 1.50A 3eeyJ-3mi9A:
2.4		 3eeyJ-3mi9A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
VAL A  79
LEU A 156
ALA A 166
 None
 0.68A 3gvuA-3mi9A:
16.5		 3gvuA-3mi9A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 ALA A  46
GLU A  66
VAL A  79
LEU A 156
ALA A 166
 None
 0.60A 3ik3A-3mi9A:
22.9		 3ik3A-3mi9A:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 ALA A  46
VAL A  79
HIS A 147
LEU A 156
ALA A 166
 None
 0.49A 3ik3A-3mi9A:
22.9		 3ik3A-3mi9A:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 ALA A  46
GLU A  66
VAL A  79
LEU A 156
ALA A 166
 None
 0.56A 3ik3B-3mi9A:
22.7		 3ik3B-3mi9A:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 ALA A  46
VAL A  79
HIS A 147
LEU A 156
ALA A 166
 None
 0.50A 3ik3B-3mi9A:
22.7		 3ik3B-3mi9A:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
PHE A 105
LEU A 156
ALA A 166
 None
 0.66A 3k5vA-3mi9A:
22.3		 3k5vA-3mi9A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
PHE A 105
LEU A 156
ALA A 166
 None
 0.65A 3k5vB-3mi9A:
22.2		 3k5vB-3mi9A:
26.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LFA_A_1N1A361_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 8 ALA A  46
LYS A  48
GLU A  66
LEU A 101
 None
 0.31A 3lfaA-3mi9A:
22.0		 3lfaA-3mi9A:
32.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 VAL A 155
LEU A 163
ALA A 171
GLY A 214
ALA A 215
 None
 0.91A 3ln1A-3mi9A:
undetectable		 3ln1A-3mi9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 VAL A 155
LEU A 163
ALA A 171
GLY A 214
ALA A 215
 None
 0.91A 3ln1B-3mi9A:
undetectable		 3ln1B-3mi9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 VAL A 155
LEU A 163
ALA A 171
GLY A 214
ALA A 215
 None
 0.91A 3ln1C-3mi9A:
undetectable		 3ln1C-3mi9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 VAL A 155
LEU A 163
ALA A 171
GLY A 214
ALA A 215
 None
 0.90A 3ln1D-3mi9A:
undetectable		 3ln1D-3mi9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIY_A_B49A1_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 11 ILE A  25
ALA A  46
LYS A  48
VAL A  79
PHE A 103
PHE A 105
LEU A 156
 None
 0.87A 3miyA-3mi9A:
23.3		 3miyA-3mi9A:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIY_B_B49B2_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 9 ILE A  25
ALA A  46
LYS A  48
PHE A 103
PHE A 105
LEU A 156
 None
 0.83A 3miyB-3mi9A:
23.2		 3miyB-3mi9A:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
PHE A 105
LEU A 156
ALA A 166
 None
 0.70A 3ms9A-3mi9A:
22.1		 3ms9A-3mi9A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
ILE A  69
PHE A 105
LEU A 156
ALA A 166
 None
 1.03A 3ms9A-3mi9A:
22.1		 3ms9A-3mi9A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
PHE A 105
LEU A 156
ALA A 166
 None
 0.71A 3mssA-3mi9A:
22.1		 3mssA-3mi9A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
ILE A  69
PHE A 105
LEU A 156
ALA A 166
 None
 1.06A 3mssA-3mi9A:
22.1		 3mssA-3mi9A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
PHE A 105
LEU A 156
ALA A 166
 None
 0.71A 3mssB-3mi9A:
22.3		 3mssB-3mi9A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
PHE A 105
LEU A 156
ALA A 166
 None
 0.72A 3mssC-3mi9A:
22.0		 3mssC-3mi9A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
ILE A  69
PHE A 105
LEU A 156
ALA A 166
 None
 1.05A 3mssC-3mi9A:
22.0		 3mssC-3mi9A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
VAL A  79
LEU A 156
ALA A 166
 None
 0.58A 3oezA-3mi9A:
22.0		 3oezA-3mi9A:
27.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OG7_A_032A1_1
(AKAP9-BRAF FUSION
PROTEIN)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
LYS A  48
LEU A  70
CYH A 106
PHE A 168
 None
 1.05A 3og7A-3mi9A:
16.8		 3og7A-3mi9A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 LEU A 165
TYR A 194
GLY A 214
LEU A 134
ALA A 220
 None
 1.07A 3ou7B-3mi9A:
undetectable		 3ou7B-3mi9A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 11 VAL A 155
LEU A 163
TYR A 194
GLY A 214
ALA A 215
 None
 0.92A 3pghB-3mi9A:
undetectable		 3pghB-3mi9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 VAL A 155
LEU A 163
TYR A 194
GLY A 214
ALA A 215
 None
 0.93A 3pghC-3mi9A:
undetectable		 3pghC-3mi9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 VAL A 155
LEU A 163
TYR A 194
GLY A 214
ALA A 215
 None
 0.91A 3pghD-3mi9A:
undetectable		 3pghD-3mi9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
PHE A 105
LEU A 156
ALA A 166
 None
 0.72A 3pyyA-3mi9A:
22.4		 3pyyA-3mi9A:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
GLU A  66
VAL A  79
LEU A 156
ALA A 166
 None
 0.66A 3pyyB-3mi9A:
22.1		 3pyyB-3mi9A:
25.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 VAL A  33
ALA A  46
GLU A  66
LEU A  70
PHE A 103
HIS A 147
ALA A 166
 None
 0.59A 3rgfA-3mi9A:
11.4		 3rgfA-3mi9A:
32.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 9 ILE A  25
ALA A  46
PHE A 103
PHE A 105
ASP A 109
LEU A 156
 None
 0.57A 3ti1A-3mi9A:
30.0		 3ti1A-3mi9A:
39.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 9 ILE A  25
ALA A  46
VAL A  79
PHE A 105
ASP A 109
LEU A 156
 None
 0.75A 3ti1A-3mi9A:
30.0		 3ti1A-3mi9A:
39.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 9 ILE A  25
PHE A 103
PHE A 105
ASP A 109
LEU A 156
ASP A 167
 None
 0.77A 3ti1A-3mi9A:
30.0		 3ti1A-3mi9A:
39.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 9 ILE A  25
VAL A  79
PHE A 105
ASP A 109
LEU A 156
ASP A 167
 None
 0.80A 3ti1A-3mi9A:
30.0		 3ti1A-3mi9A:
39.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 8 VAL A  33
LYS A  48
PHE A 103
ASP A 167
 None
 0.48A 3warA-3mi9A:
30.8		 3warA-3mi9A:
27.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 5 ILE A  69
VAL A  79
LEU A 156
ASP A 167
 None
 1.00A 3wzdA-3mi9A:
22.3		 3wzdA-3mi9A:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 8 VAL A  78
VAL A  79
CYH A 106
LEU A 156
 None
 0.27A 3wzeA-3mi9A:
2.7		 3wzeA-3mi9A:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 ALA A  46
LYS A  48
GLU A  66
HIS A 147
ARG A 148
LEU A 156
ALA A 166
 None
None
None
None
TPO  A 186 ( 2.8A)
None
None
 0.68A 3zosA-3mi9A:
14.9		 3zosA-3mi9A:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 ALA A  46
LYS A  48
GLU A  66
HIS A 147
ARG A 148
LEU A 156
ALA A 166
 None
None
None
None
TPO  A 186 ( 2.8A)
None
None
 0.67A 3zosB-3mi9A:
22.0		 3zosB-3mi9A:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGD_A_B49A2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 11 ALA A  46
LYS A  48
VAL A  79
PHE A 105
CYH A 106
LEU A 156
 None
 0.62A 4agdA-3mi9A:
21.4		 4agdA-3mi9A:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 ALA A  46
LYS A  48
GLU A  66
LEU A  70
HIS A 147
LEU A 156
ALA A 166
 None
 0.68A 4c8bA-3mi9A:
23.3		 4c8bA-3mi9A:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 ALA A  46
LYS A  48
GLU A  66
LEU A  70
HIS A 147
LEU A 156
ALA A 166
 None
 0.76A 4c8bB-3mi9A:
16.5		 4c8bB-3mi9A:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 VAL A  33
ALA A  46
GLU A  66
ILE A  69
VAL A  79
LEU A 156
ALA A 166
 None
 0.84A 4csvA-3mi9A:
23.0		 4csvA-3mi9A:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM0_B_KANB302_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 11 LEU A 267
THR A 249
TYR A 262
LEU A 201
VAL A 252
 None
 1.42A 4em0B-3mi9A:
0.0		 4em0B-3mi9A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MKC_A_4MKA1503_1
(ALK TYROSINE KINASE
RECEPTOR)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
LYS A  48
ASP A 109
LEU A 156
ASP A 167
 None
 0.59A 4mkcA-3mi9A:
22.6		 4mkcA-3mi9A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 LEU A 133
ILE A 218
ALA A 166
ALA A 171
ILE A 140
 None
 0.96A 4nkxD-3mi9A:
undetectable		 4nkxD-3mi9A:
22.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_A_ADNA401_1
(CYCLIN-DEPENDENT
KINASE 9)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 8 ILE A  25
ALA A  46
ASP A 109
ASN A 154
LEU A 156
ASP A 167
 None
 0.51A 4ogrA-3mi9A:
46.0		 4ogrA-3mi9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_A_ADNA401_1
(CYCLIN-DEPENDENT
KINASE 9)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 8 ILE A  25
VAL A  33
ALA A  46
ASP A 109
ASN A 154
LEU A 156
 None
 0.63A 4ogrA-3mi9A:
46.0		 4ogrA-3mi9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_E_ADNE401_1
(CYCLIN-DEPENDENT
KINASE 9)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 7 ALA A  46
CYH A 106
ASP A 109
ASN A 154
LEU A 156
ASP A 167
 None
 0.31A 4ogrE-3mi9A:
47.1		 4ogrE-3mi9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_E_ADNE401_1
(CYCLIN-DEPENDENT
KINASE 9)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 7 GLY A  26
ALA A  46
CYH A 106
ASP A 109
LEU A 156
 None
 0.99A 4ogrE-3mi9A:
47.1		 4ogrE-3mi9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_I_ADNI401_1
(CYCLIN-DEPENDENT
KINASE 9)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		8 / 9 ILE A  25
VAL A  33
ALA A  46
CYH A 106
ASP A 109
ASN A 154
LEU A 156
ASP A 167
 None
 0.69A 4ogrI-3mi9A:
45.5		 4ogrI-3mi9A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
LYS A  48
GLU A  66
CYH A 106
LEU A 156
 None
 0.77A 4r7iA-3mi9A:
21.6		 4r7iA-3mi9A:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 ALA A  46
GLU A  66
HIS A 147
LEU A 156
ALA A 166
 None
 0.69A 4tyjA-3mi9A:
22.3		 4tyjA-3mi9A:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U0I_A_0LIA1001_2
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 ALA A  46
LYS A  48
LEU A  70
CYH A 106
HIS A 147
LEU A 156
 None
 0.47A 4u0iA-3mi9A:
21.9		 4u0iA-3mi9A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  33
ALA A  46
LYS A  48
CYH A 106
ASP A 167
PHE A 168
 None
 0.97A 4xv2A-3mi9A:
22.6		 4xv2A-3mi9A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 ALA A  46
LYS A  48
LEU A  70
CYH A 106
ASP A 167
PHE A 168
 None
 0.83A 4xv2B-3mi9A:
17.5		 4xv2B-3mi9A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 GLY A  26
ALA A  46
PHE A 105
CYH A 106
LEU A 156
ALA A 166
ASP A 167
 None
 0.63A 5ajqA-3mi9A:
25.2		 5ajqA-3mi9A:
29.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 VAL A  33
ALA A  46
LYS A  48
LEU A  70
PHE A 168
 None
 0.81A 5cswB-3mi9A:
17.6		 5cswB-3mi9A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 5 TYR A 194
TRP A 213
LEU A 133
LEU A 114
 None
 1.38A 5eshA-3mi9A:
undetectable		 5eshA-3mi9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 11 PHE A  59
ILE A  67
LEU A  73
GLY A 169
ALA A 173
 None
 1.39A 5fctA-3mi9A:
undetectable		 5fctA-3mi9A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 ALA A  46
LYS A  48
GLU A  66
LEU A  70
CYH A 106
HIS A 147
 None
 0.70A 5hi2A-3mi9A:
14.9		 5hi2A-3mi9A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 7 ILE A  25
CYH A 106
ASP A 167
PHE A 168
 None
 0.83A 5hieA-3mi9A:
22.7		 5hieA-3mi9A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 7 ILE A  25
CYH A 106
ASP A 167
PHE A 168
 None
 0.83A 5hieB-3mi9A:
6.9		 5hieB-3mi9A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 8 ILE A  25
CYH A 106
ASP A 167
PHE A 168
 None
 0.81A 5hieD-3mi9A:
22.5		 5hieD-3mi9A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 6 PRO A 196
HIS A 147
GLU A  66
ALA A 173
 None
 0.93A 5igiA-3mi9A:
8.0		 5igiA-3mi9A:
21.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2I_A_LQQA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 ALA A  46
VAL A  79
PHE A 103
ASP A 109
LEU A 156
ALA A 166
ASP A 167
 None
 0.82A 5l2iA-3mi9A:
12.6		 5l2iA-3mi9A:
36.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2I_A_LQQA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		8 / 12 ILE A  25
VAL A  33
ALA A  46
VAL A  79
PHE A 103
ASP A 109
LEU A 156
ALA A 166
 None
 0.78A 5l2iA-3mi9A:
12.6		 5l2iA-3mi9A:
36.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		9 / 12 ILE A  25
GLY A  26
VAL A  33
ALA A  46
VAL A  79
PHE A 103
ASP A 109
LEU A 156
ALA A 166
 None
 0.83A 5l2tA-3mi9A:
12.9		 5l2tA-3mi9A:
36.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		6 / 12 VAL A  79
PHE A 103
ASP A 109
LEU A 156
ALA A 166
ASP A 167
 None
 0.73A 5l2tA-3mi9A:
12.9		 5l2tA-3mi9A:
36.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_2
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 5 LEU A  70
CYH A 106
LEU A 156
ASP A 167
 None
 0.80A 5mafA-3mi9A:
25.4		 5mafA-3mi9A:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 ALA A  46
VAL A  79
HIS A 147
LEU A 156
ALA A 166
 None
 0.60A 5mo4A-3mi9A:
19.8		 5mo4A-3mi9A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 GLY A 214
LEU A 200
LEU A 201
GLU A 198
LEU A 199
 None
 1.06A 5nwwA-3mi9A:
undetectable		 5nwwA-3mi9A:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OWR_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 8 ALA A  46
GLU A  66
CYH A 106
LEU A 156
ASP A 167
 None
 0.35A 5owrA-3mi9A:
23.6		 5owrA-3mi9A:
28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 LEU A 212
MET A 150
ALA A 171
LEU A 110
LEU A 163
 None
 1.18A 5tudA-3mi9A:
2.3		 5tudA-3mi9A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 8 VAL A  33
LYS A  48
PHE A 103
ASP A 167
 None
 0.48A 5y9mA-3mi9A:
31.2		 5y9mA-3mi9A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 8 VAL A  33
LYS A  48
PHE A 103
ASP A 167
 None
 0.45A 5y9mX-3mi9A:
31.2		 5y9mX-3mi9A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 7 VAL A  33
LYS A  48
PHE A 103
ASP A 167
 None
 0.45A 5yf9B-3mi9A:
31.0		 5yf9B-3mi9A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 7 VAL A  33
LYS A  48
PHE A 103
ASP A 167
 None
 0.57A 5ywmX-3mi9A:
31.3		 5ywmX-3mi9A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		4 / 6 LEU A 137
LEU A 133
TYR A 194
LEU A 295
 None
 0.88A 6f6sA-3mi9A:
undetectable
6f6sB-3mi9A:
undetectable		 6f6sA-3mi9A:
13.53
6f6sB-3mi9A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		7 / 12 VAL A  33
ALA A  46
GLU A  66
VAL A  79
PHE A 105
LEU A 156
ALA A 166
 None
 0.70A 6hd6A-3mi9A:
22.3		 6hd6A-3mi9A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 3mi9 CELL DIVISION
PROTEIN KINASE 9
(Homo
sapiens) 		5 / 12 LEU A 289
LEU A 114
GLY A 216
TYR A 194
ILE A 228
 None
 1.27A 6qyaD-3mi9A:
undetectable		 6qyaD-3mi9A:
21.29