SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3miz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		4 / 6 ARG A 333
ASP A  77
TYR A 300
ASP A  84
 None
 1.30A 1rjdA-3mizA:
undetectable		 1rjdA-3mizA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		4 / 6 ARG A 333
ASP A  77
TYR A 300
ASP A  84
 None
 1.31A 1rjdB-3mizA:
undetectable		 1rjdB-3mizA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		4 / 6 ARG A 333
ASP A  77
TYR A 300
ASP A  84
 None
 1.32A 1rjdC-3mizA:
undetectable		 1rjdC-3mizA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		5 / 11 ALA A 255
ILE A 183
ILE A 275
ALA A 234
VAL A 230
 None
 1.20A 2qhfA-3mizA:
undetectable		 2qhfA-3mizA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		4 / 6 THR A 141
GLY A 119
ILE A 117
LEU A 121
 None
 1.22A 4ac9C-3mizA:
2.1		 4ac9C-3mizA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		4 / 6 THR A 141
GLY A 119
ILE A 117
LEU A 121
 None
 1.26A 4acaC-3mizA:
undetectable		 4acaC-3mizA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		4 / 7 ARG A 304
GLY A 303
ILE A 157
GLN A  83
 None
 0.80A 4g0vA-3mizA:
3.2		 4g0vA-3mizA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		4 / 7 ARG A 304
GLY A 303
ILE A 157
GLU A 305
 None
 0.99A 4g0vA-3mizA:
3.2		 4g0vA-3mizA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		5 / 12 GLY A 250
TYR A 259
SER A 216
ALA A 192
GLU A 193
 None
 1.28A 4ymgA-3mizA:
undetectable		 4ymgA-3mizA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		3 / 3 VAL A 331
THR A 294
ARG A 333
 None
 0.73A 5b2sB-3mizA:
undetectable		 5b2sB-3mizA:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		3 / 3 VAL A 331
THR A 294
ARG A 333
 None
 0.74A 5b2tB-3mizA:
undetectable		 5b2tB-3mizA:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		3 / 3 PRO A 298
ILE A  93
SER A 327
 None
 0.78A 5fsaA-3mizA:
undetectable		 5fsaA-3mizA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		5 / 12 ILE A 183
GLY A 250
LEU A 288
LEU A 172
LEU A 168
 None
 1.03A 5ycnA-3mizA:
undetectable		 5ycnA-3mizA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		4 / 7 LEU A 267
ASP A 272
ARG A 243
GLN A 271
 None
 1.36A 6g31D-3mizA:
undetectable		 6g31D-3mizA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3miz PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN,
LACI FAMILY
(Rhizobium
etli) 		4 / 6 LEU A 267
ASP A 272
ARG A 243
GLN A 271
 None
 1.34A 6g31J-3mizA:
undetectable		 6g31J-3mizA:
16.72