SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mj8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
LIGHT CHAIN
(Cricetulus
migratorius) 		3 / 3 VAL L  31
VAL L  33
TRP L  91
 None
 0.97A 1bdwA-3mj8L:
undetectable
1bdwB-3mj8L:
undetectable		 1bdwA-3mj8L:
6.18
1bdwB-3mj8L:
6.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
HEAVY CHAIN
STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
LIGHT CHAIN
(Cricetulus
migratorius) 		6 / 12 TYR L  36
GLN L  89
PHE L  98
VAL H  37
ALA H  93
TRP H 103
 None
 0.65A 1h8sA-3mj8L:
17.4		 1h8sA-3mj8L:
32.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
HEAVY CHAIN
(Cricetulus
migratorius) 		4 / 7 THR H  73
SER H  74
SER H  70
ARG H  71
 None
 1.14A 1ibgL-3mj8H:
17.0		 1ibgL-3mj8H:
27.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
LIGHT CHAIN
(Cricetulus
migratorius) 		5 / 12 ASP L  85
LYS L 103
PRO L   7
GLY L  99
LEU L   4
 None
 1.35A 2nv4A-3mj8L:
undetectable		 2nv4A-3mj8L:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
LIGHT CHAIN
(Cricetulus
migratorius) 		4 / 7 LEU L 132
ALA L 130
LEU L 179
THR L 182
 None
 1.04A 3cfqA-3mj8L:
4.3
3cfqB-3mj8L:
undetectable		 3cfqA-3mj8L:
24.27
3cfqB-3mj8L:
24.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)		 3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
LIGHT CHAIN
(Cricetulus
migratorius) 		5 / 7 TYR L  32
TYR L  36
TYR L  49
GLU L  50
PRO L  55
 None
 0.87A 5aclA-3mj8L:
20.0		 5aclA-3mj8L:
60.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
LIGHT CHAIN
(Cricetulus
migratorius) 		4 / 6 LEU L 132
ALA L 130
LEU L 179
THR L 182
 None
 1.07A 5bojA-3mj8L:
undetectable		 5bojA-3mj8L:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
LIGHT CHAIN
(Cricetulus
migratorius) 		4 / 6 LEU L 132
ALA L 130
LEU L 179
THR L 182
 None
 1.04A 5l4iA-3mj8L:
undetectable		 5l4iA-3mj8L:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
LIGHT CHAIN
(Cricetulus
migratorius) 		4 / 8 THR L  20
SER L  63
ALA L  71
ASP L  51
 None
 1.10A 5l5fY-3mj8L:
undetectable
5l5fZ-3mj8L:
undetectable		 5l5fY-3mj8L:
21.69
5l5fZ-3mj8L:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
HEAVY CHAIN
STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
LIGHT CHAIN
(Cricetulus
migratorius) 		4 / 8 PRO H 175
THR L 161
THR L 162
PRO L 113
 None
 1.25A 5x2sI-3mj8H:
undetectable
5x2sJ-3mj8H:
undetectable
5x2sK-3mj8H:
undetectable		 5x2sI-3mj8H:
22.27
5x2sJ-3mj8H:
21.23
5x2sK-3mj8H:
22.27