SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mj9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		3 / 3 GLU A  19
HIS A  16
ASP A 198
 None
 0.88A 1i9gA-3mj9A:
undetectable		 1i9gA-3mj9A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		3 / 3 ARG A 147
GLY A  82
ASP A  81
 None
 0.57A 1kf6A-3mj9A:
undetectable
1kf6B-3mj9A:
undetectable		 1kf6A-3mj9A:
15.89
1kf6B-3mj9A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.11A 1zzrA-3mj9A:
undetectable
1zzrB-3mj9A:
undetectable		 1zzrA-3mj9A:
21.36
1zzrB-3mj9A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.12A 1zzrA-3mj9A:
undetectable
1zzrB-3mj9A:
undetectable		 1zzrA-3mj9A:
21.36
1zzrB-3mj9A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.12A 1zzuA-3mj9A:
undetectable
1zzuB-3mj9A:
undetectable		 1zzuA-3mj9A:
21.36
1zzuB-3mj9A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.11A 1zzuA-3mj9A:
undetectable
1zzuB-3mj9A:
undetectable		 1zzuA-3mj9A:
21.36
1zzuB-3mj9A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 ARG A  70
SER A  71
PHE A  67
ARG A  66
 None
 1.10A 2c8aA-3mj9A:
undetectable		 2c8aA-3mj9A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		5 / 12 SER A 217
ARG A 183
THR A 215
LEU A 203
ILE A 201
 None
 1.17A 2fj1A-3mj9A:
undetectable		 2fj1A-3mj9A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 166
THR A 165
PHE A 184
ARG A 185
 None
 1.27A 2kotA-3mj9A:
undetectable		 2kotA-3mj9A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.12A 3dqrA-3mj9A:
undetectable
3dqrB-3mj9A:
undetectable		 3dqrA-3mj9A:
21.26
3dqrB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.08A 3jx2A-3mj9A:
undetectable
3jx2B-3mj9A:
undetectable		 3jx2A-3mj9A:
21.26
3jx2B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.09A 3jx2A-3mj9A:
undetectable
3jx2B-3mj9A:
undetectable		 3jx2A-3mj9A:
21.26
3jx2B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.14A 3jx3A-3mj9A:
undetectable
3jx3B-3mj9A:
undetectable		 3jx3A-3mj9A:
21.26
3jx3B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.07A 3jx3A-3mj9A:
undetectable
3jx3B-3mj9A:
undetectable		 3jx3A-3mj9A:
21.26
3jx3B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.09A 3jx4A-3mj9A:
undetectable
3jx4B-3mj9A:
undetectable		 3jx4A-3mj9A:
21.26
3jx4B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.10A 3jx5A-3mj9A:
undetectable
3jx5B-3mj9A:
undetectable		 3jx5A-3mj9A:
21.26
3jx5B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.04A 3jx6A-3mj9A:
undetectable
3jx6B-3mj9A:
undetectable		 3jx6A-3mj9A:
21.26
3jx6B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.05A 3jx6A-3mj9A:
undetectable
3jx6B-3mj9A:
undetectable		 3jx6A-3mj9A:
21.26
3jx6B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.04A 3nljA-3mj9A:
undetectable
3nljB-3mj9A:
undetectable		 3nljA-3mj9A:
21.26
3nljB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.02A 3nljA-3mj9A:
undetectable
3nljB-3mj9A:
undetectable		 3nljA-3mj9A:
21.26
3nljB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.07A 3nlpA-3mj9A:
undetectable
3nlpB-3mj9A:
undetectable		 3nlpA-3mj9A:
21.26
3nlpB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 8 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.06A 3nlqA-3mj9A:
undetectable
3nlqB-3mj9A:
undetectable		 3nlqA-3mj9A:
21.26
3nlqB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.06A 3nlqA-3mj9A:
undetectable
3nlqB-3mj9A:
undetectable		 3nlqA-3mj9A:
21.26
3nlqB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.08A 3nlrA-3mj9A:
undetectable
3nlrB-3mj9A:
undetectable		 3nlrA-3mj9A:
21.26
3nlrB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 8 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.07A 3nlrA-3mj9A:
undetectable
3nlrB-3mj9A:
undetectable		 3nlrA-3mj9A:
21.26
3nlrB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		3 / 3 THR A  30
ASN A  80
GLU A  32
 FUC  A 506 (-3.1A)
FUC  A 506 (-3.9A)
None
 0.81A 3v4tA-3mj9A:
undetectable
3v4tC-3mj9A:
undetectable		 3v4tA-3mj9A:
19.81
3v4tC-3mj9A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		3 / 3 ASP A  48
LYS A  46
ASP A  45
 None
 0.81A 4a7tA-3mj9A:
undetectable		 4a7tA-3mj9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.13A 4cx3A-3mj9A:
undetectable
4cx3B-3mj9A:
undetectable		 4cx3A-3mj9A:
21.26
4cx3B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.09A 4cx3A-3mj9A:
undetectable
4cx3B-3mj9A:
undetectable		 4cx3A-3mj9A:
21.26
4cx3B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.13A 4cx4A-3mj9A:
undetectable
4cx4B-3mj9A:
undetectable		 4cx4A-3mj9A:
21.26
4cx4B-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.04A 5addA-3mj9A:
undetectable
5addB-3mj9A:
undetectable		 5addA-3mj9A:
21.26
5addB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 GLU A  94
VAL A 118
ARG A  70
VAL A  21
 None
 1.00A 5adeA-3mj9A:
undetectable
5adeB-3mj9A:
undetectable		 5adeA-3mj9A:
21.26
5adeB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		4 / 7 VAL A 118
ARG A  70
VAL A  21
GLU A  94
 None
 1.08A 5g0pA-3mj9A:
undetectable
5g0pB-3mj9A:
undetectable		 5g0pA-3mj9A:
21.26
5g0pB-3mj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 3mj9 JUNCTIONAL ADHESION
MOLECULE-LIKE
(Mus
musculus) 		3 / 3 TRP A 153
ILE A 229
GLU A  19
 None
 0.83A 6hcxA-3mj9A:
undetectable		 6hcxA-3mj9A:
14.94