SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mjg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H21_A_SAMA801_0 (RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE/OXYGENAS E)	3mjg	BETA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR (Homo sapiens)	5 / 10	GLY X 92 LEU X 93 ARG X 64 TYR X 117 PHE X 119	None	1.46A	2h21A-3mjgX: undetectable	2h21A-3mjgX: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_B_CHDB500_0 (ILEAL BILE ACID-BINDING PROTEIN)	3mjg	BETA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR (Homo sapiens)	4 / 7	GLU X 72 VAL X 84 THR X 86 VAL X 51	None	0.60A	3em0B-3mjgX: undetectable	3em0B-3mjgX: 18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	3mjg	PLATELET-DERIVED GROWTH FACTOR SUBUNIT B (Homo sapiens)	4 / 6	LEU A 91 VAL A 89 LEU A 29 VAL A 72	None	0.79A	5x7zA-3mjgA: undetectable	5x7zA-3mjgA: 22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZSF_B_6T0B913_0 (TOLL-LIKE RECEPTOR 7)	3mjg	BETA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR (Homo sapiens)	5 / 9	TYR X 249 VAL X 258 LEU X 233 ILE X 275 THR X 232	None	1.32A	5zsfA-3mjgX: 0.0 5zsfB-3mjgX: 0.0	5zsfA-3mjgX: 15.41 5zsfB-3mjgX: 15.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2H21_A_SAMA801_0","RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE\/OXYGENASE","3mjg","BETA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR","Homo sapiens",5,"GLY X  92;LEU X  93;ARG X  64;TYR X 117;PHE X 119","None","1.46A","2h21A-3mjgX:undetectable","2h21A-3mjgX:20.44"],["3EM0_B_CHDB500_0","ILEAL BILE ACID-BINDING PROTEIN","3mjg","BETA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR","Homo sapiens",4,"GLU X  72;VAL X  84;THR X  86;VAL X  51","None","0.60A","3em0B-3mjgX:undetectable","3em0B-3mjgX:18.37"],["5X7Z_A_BHAA201_0","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887","3mjg","PLATELET-DERIVED GROWTH FACTOR SUBUNIT B","Homo sapiens",4,"LEU A  91;VAL A  89;LEU A  29;VAL A  72","None","0.79A","5x7zA-3mjgA:undetectable","5x7zA-3mjgA:22.95"],["5ZSF_B_6T0B913_0","TOLL-LIKE RECEPTOR 7","3mjg","BETA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR","Homo sapiens",5,"TYR X 249;VAL X 258;LEU X 233;ILE X 275;THR X 232","None","1.32A","5zsfA-3mjgX:0.0;5zsfB-3mjgX:0.0","5zsfA-3mjgX:15.41;5zsfB-3mjgX:15.41"]]