SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mjo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 7 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.82A 11gsA-3mjoA:
undetectable		 11gsA-3mjoA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 7 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.82A 11gsB-3mjoA:
undetectable		 11gsB-3mjoA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 LEU A 171
ASP A  77
LEU A  73
LEU A  76
 None
MN3  A1001 (-2.2A)
None
None
 1.07A 1e7cA-3mjoA:
undetectable		 1e7cA-3mjoA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		3 / 3 GLU A 278
TYR A 277
PHE A 233
 None
 0.95A 1eqbB-3mjoA:
undetectable		 1eqbB-3mjoA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		3 / 3 GLU A 278
TYR A 277
PHE A 233
 None
 0.95A 1eqbD-3mjoA:
undetectable		 1eqbD-3mjoA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F86_A_T44A428_1
(TRANSTHYRETIN
THR119MET VARIANT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 4 LYS A 144
LEU A 171
ALA A 145
LEU A 167
 None
 1.50A 1f86A-3mjoA:
undetectable		 1f86A-3mjoA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 5 LEU A 235
VAL A 162
TYR A 151
THR A 232
 None
 1.38A 1nw3A-3mjoA:
0.9		 1nw3A-3mjoA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 LEU A 272
ASN A 273
LEU A 275
GLY A 276
THR A 283
 None
 1.42A 1p93A-3mjoA:
3.3		 1p93A-3mjoA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 ASP A  77
GLU A 108
HIS A 111
LEU A 167
GLU A 168
PHE A 176
ILE A 198
GLU A 202
 MN3  A1001 (-2.2A)
MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
MN3  A1002 (-2.9A)
None
None
MN3  A1002 (-2.6A)
 0.85A 1rnrA-3mjoA:
31.4		 1rnrA-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 ASP A  77
GLU A 108
HIS A 111
LEU A 167
GLU A 168
TYR A 173
PHE A 176
ILE A 198
 MN3  A1001 (-2.2A)
MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
MN3  A1002 (-2.9A)
None
None
None
 0.70A 1rnrA-3mjoA:
31.4		 1rnrA-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 12 ASP A  77
GLU A 108
HIS A 111
LEU A 167
GLU A 168
PHE A 176
ILE A 198
GLU A 202
 MN3  A1001 (-2.2A)
MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
MN3  A1002 (-2.9A)
None
None
MN3  A1002 (-2.6A)
 0.79A 1rnrB-3mjoA:
31.8		 1rnrB-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 12 ASP A  77
GLU A 108
HIS A 111
LEU A 167
GLU A 168
TYR A 173
PHE A 176
ILE A 198
 MN3  A1001 (-2.2A)
MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
MN3  A1002 (-2.9A)
None
None
None
 0.64A 1rnrB-3mjoA:
31.8		 1rnrB-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 12 GLU A 108
HIS A 111
TYR A 115
LEU A 167
GLU A 168
PHE A 176
ILE A 198
GLU A 202
 MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
None
MN3  A1002 (-2.9A)
None
None
MN3  A1002 (-2.6A)
 0.81A 1rnrB-3mjoA:
31.8		 1rnrB-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 12 GLU A 108
HIS A 111
TYR A 115
LEU A 167
GLU A 168
TYR A 173
PHE A 176
ILE A 198
 MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
None
MN3  A1002 (-2.9A)
None
None
None
 0.64A 1rnrB-3mjoA:
31.8		 1rnrB-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 LEU A 166
TYR A 213
GLY A 206
LEU A 272
 None
 0.99A 1s1xA-3mjoA:
undetectable		 1s1xA-3mjoA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.83A 2gssA-3mjoA:
undetectable		 2gssA-3mjoA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.82A 2gssB-3mjoA:
undetectable		 2gssB-3mjoA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_A_T44A128_1
(TRANSTHYRETIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 4 LYS A 144
LEU A 171
ALA A 145
LEU A 167
 None
 1.42A 2roxA-3mjoA:
undetectable		 2roxA-3mjoA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 7 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.90A 3gssA-3mjoA:
undetectable		 3gssA-3mjoA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 7 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.90A 3gssB-3mjoA:
undetectable		 3gssB-3mjoA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_2
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 6 THR A  71
ASN A 138
TRP A 134
TRP A 256
 None
 1.29A 3jzjA-3mjoA:
0.0		 3jzjA-3mjoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 11 SER A 203
LEU A 272
LEU A 166
SER A 169
PHE A 170
 None
 0.94A 3ko0A-3mjoA:
0.8
3ko0B-3mjoA:
1.0
3ko0I-3mjoA:
0.7
3ko0J-3mjoA:
0.7		 3ko0A-3mjoA:
17.12
3ko0B-3mjoA:
17.12
3ko0I-3mjoA:
17.12
3ko0J-3mjoA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 LEU A 166
SER A 169
PHE A 170
LEU A 272
SER A 203
 None
 1.22A 3ko0K-3mjoA:
1.0
3ko0L-3mjoA:
0.8
3ko0S-3mjoA:
0.7
3ko0T-3mjoA:
0.7		 3ko0K-3mjoA:
17.12
3ko0L-3mjoA:
17.12
3ko0S-3mjoA:
17.12
3ko0T-3mjoA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 LEU A 166
SER A 169
PHE A 170
LEU A 272
SER A 203
 None
 0.93A 3ko0M-3mjoA:
1.0
3ko0N-3mjoA:
undetectable
3ko0O-3mjoA:
0.8
3ko0P-3mjoA:
1.0		 3ko0M-3mjoA:
17.12
3ko0N-3mjoA:
17.12
3ko0O-3mjoA:
17.12
3ko0P-3mjoA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 SER A 203
LEU A 272
LEU A 166
SER A 169
PHE A 170
 None
 0.93A 3ko0M-3mjoA:
1.0
3ko0N-3mjoA:
undetectable
3ko0O-3mjoA:
0.8
3ko0P-3mjoA:
1.0		 3ko0M-3mjoA:
17.12
3ko0N-3mjoA:
17.12
3ko0O-3mjoA:
17.12
3ko0P-3mjoA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.81A 3n9jA-3mjoA:
undetectable		 3n9jA-3mjoA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.82A 3n9jB-3mjoA:
undetectable		 3n9jB-3mjoA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 10 ILE A 199
ALA A 192
PHE A 176
SER A 114
ILE A 198
 None
 1.25A 3qgtA-3mjoA:
undetectable		 3qgtA-3mjoA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_A_ADNA403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 ASP A  77
PHE A 172
ASP A 201
ILE A 199
ILE A 195
 MN3  A1001 (-2.2A)
MN3  A1001 ( 4.5A)
None
None
None
 1.23A 4ktvA-3mjoA:
undetectable
4ktvB-3mjoA:
undetectable		 4ktvA-3mjoA:
20.35
4ktvB-3mjoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_C_ADNC403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 11 ASP A  77
PHE A 172
ASP A 201
ILE A 199
ILE A 195
 MN3  A1001 (-2.2A)
MN3  A1001 ( 4.5A)
None
None
None
 1.28A 4ktvC-3mjoA:
undetectable
4ktvD-3mjoA:
undetectable		 4ktvC-3mjoA:
20.35
4ktvD-3mjoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 GLY A  81
GLN A  80
ALA A 105
LEU A  89
SER A 164
 None
 1.18A 4pb1A-3mjoA:
undetectable		 4pb1A-3mjoA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 GLY A  81
GLN A  80
ALA A 105
LEU A  89
SER A 164
 None
 1.21A 4pd5A-3mjoA:
0.2		 4pd5A-3mjoA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 GLY A  81
GLN A  80
ALA A 105
LEU A  89
SER A 164
 None
 1.16A 4pd9A-3mjoA:
undetectable		 4pd9A-3mjoA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 PHE A 176
ILE A 199
HIS A 111
GLU A 108
ASP A  77
 None
None
MN3  A1001 (-3.2A)
MN3  A1002 ( 2.4A)
MN3  A1001 (-2.2A)
 1.34A 4r88A-3mjoA:
undetectable		 4r88A-3mjoA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		3 / 3 ALA A 271
ASN A 274
LEU A 275
 None
 0.49A 5i1oA-3mjoA:
undetectable		 5i1oA-3mjoA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 5 TYR A 173
GLU A 168
GLY A 206
SER A 203
 None
MN3  A1002 (-2.9A)
None
None
 1.19A 5jhdJ-3mjoA:
undetectable		 5jhdJ-3mjoA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 7 LEU A  73
PHE A  70
THR A 191
THR A 247
 None
 0.97A 5vc0A-3mjoA:
undetectable		 5vc0A-3mjoA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 GLY A 206
ILE A 250
LEU A  76
PHE A 176
THR A 165
 None
 1.19A 6e8qA-3mjoA:
undetectable		 6e8qA-3mjoA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 9 LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 198
 None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.71A 6ebpA-3mjoA:
41.1		 6ebpA-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		6 / 9 LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 198
 None
None
MN3  A1001 (-2.2A)
None
None
None
 0.71A 6ebpA-3mjoA:
41.1		 6ebpA-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 176
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
 0.67A 6ebpB-3mjoA:
40.8		 6ebpB-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
 0.67A 6ebpB-3mjoA:
40.8		 6ebpB-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		6 / 10 PHE A  70
LEU A  73
THR A  74
ILE A 118
PHE A 119
ILE A 198
 None
 0.34A 6ebpB-3mjoA:
40.8		 6ebpB-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.69A 6ebpC-3mjoA:
41.0		 6ebpC-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		6 / 10 PHE A  70
LEU A  73
THR A  74
SER A 114
ILE A 118
ILE A 198
 None
 0.62A 6ebpC-3mjoA:
41.0		 6ebpC-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
 0.56A 6ebpD-3mjoA:
40.8		 6ebpD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 10 PHE A  70
LEU A  73
THR A  74
ILE A 118
PHE A 119
ILE A 195
ILE A 198
 None
 0.37A 6ebpD-3mjoA:
40.8		 6ebpD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 10 PHE A  70
LEU A  73
THR A  74
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
 0.60A 6ebpD-3mjoA:
40.8		 6ebpD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.65A 6ebzA-3mjoA:
41.1		 6ebzA-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.65A 6ebzA-3mjoA:
41.1		 6ebzA-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
 0.57A 6ebzA-3mjoA:
41.1		 6ebzA-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.66A 6ebzB-3mjoA:
41.3		 6ebzB-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
 0.55A 6ebzB-3mjoA:
41.3		 6ebzB-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 11 PHE A  70
LEU A  73
THR A  74
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
 0.55A 6ebzB-3mjoA:
41.3		 6ebzB-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 11 PHE A  70
LEU A  73
SER A 114
ILE A 118
PHE A 119
PHE A 172
ILE A 198
 None
None
None
None
None
MN3  A1001 ( 4.5A)
None
 1.42A 6ebzC-3mjoA:
41.4		 6ebzC-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		9 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
None
 0.64A 6ebzC-3mjoA:
41.4		 6ebzC-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		9 / 11 PHE A  70
LEU A  73
THR A  74
SER A 114
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
 0.58A 6ebzC-3mjoA:
41.4		 6ebzC-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.68A 6ebzD-3mjoA:
41.0		 6ebzD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 11 PHE A  70
LEU A  73
THR A  74
ILE A 118
PHE A 119
ILE A 195
ILE A 198
 None
 0.37A 6ebzD-3mjoA:
41.0		 6ebzD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 11 PHE A  70
LEU A  73
THR A  74
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
 0.56A 6ebzD-3mjoA:
41.0		 6ebzD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 11 LEU A  73
ASP A  77
PHE A 176
ILE A 195
ILE A 198
 None
MN3  A1001 (-2.2A)
None
None
None
 0.85A 6gp2A-3mjoA:
40.6		 6gp2A-3mjoA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
 0.59A 6gp2A-3mjoA:
40.6		 6gp2A-3mjoA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 11 PHE A  70
LEU A  73
THR A  74
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
 0.54A 6gp2A-3mjoA:
40.6		 6gp2A-3mjoA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 11 LEU A  73
ASP A  77
PHE A 176
ILE A 195
ILE A 198
 None
MN3  A1001 (-2.2A)
None
None
None
 0.87A 6gp2B-3mjoA:
40.5		 6gp2B-3mjoA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 11 LEU A  73
THR A  74
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
 0.63A 6gp2B-3mjoA:
40.5		 6gp2B-3mjoA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 11 PHE A  70
LEU A  73
THR A  74
ILE A 118
PHE A 119
ILE A 195
ILE A 198
 None
 0.37A 6gp2B-3mjoA:
40.5		 6gp2B-3mjoA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 11 PHE A  70
LEU A  73
THR A  74
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
 0.55A 6gp2B-3mjoA:
40.5		 6gp2B-3mjoA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 VAL A  69
THR A 247
ILE A 250
PHE A 263
MET A 180
 None
 1.39A 6j20A-3mjoA:
0.9		 6j20A-3mjoA:
19.91