SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mjz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_A_CGEA501_1 (CYTOCHROME P450 2B4)	3mjz	FG41 MALONATE SEMIALDEHYDE DECARBOXYLASE (coryneform bacterium)	5 / 10	VAL A 23 ILE A 68 THR A 8 VAL A 97 VAL A 102	None	1.07A	3me6A-3mjzA: undetectable	3me6A-3mjzA: 14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_C_CGEC501_1 (CYTOCHROME P450 2B4)	3mjz	FG41 MALONATE SEMIALDEHYDE DECARBOXYLASE (coryneform bacterium)	5 / 9	VAL A 23 ILE A 68 THR A 8 VAL A 97 VAL A 102	None	1.13A	3me6C-3mjzA: undetectable	3me6C-3mjzA: 14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_D_CGED501_1 (CYTOCHROME P450 2B4)	3mjz	FG41 MALONATE SEMIALDEHYDE DECARBOXYLASE (coryneform bacterium)	5 / 9	VAL A 23 ILE A 68 THR A 8 VAL A 97 VAL A 102	None	1.07A	3me6D-3mjzA: undetectable	3me6D-3mjzA: 14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O2B_B_LOCB503_2 (TUBULIN BETA-2B CHAIN)	3mjz	FG41 MALONATE SEMIALDEHYDE DECARBOXYLASE (coryneform bacterium)	5 / 12	ALA A 87 LEU A 27 THR A 72 ILE A 68 ILE A 3	None	1.12A	4o2bB-3mjzA: undetectable	4o2bB-3mjzA: 16.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ME6_A_CGEA501_1","CYTOCHROME P450 2B4","3mjz","FG41 MALONATE SEMIALDEHYDE DECARBOXYLASE","coryneform bacterium",5,"VAL A  23;ILE A  68;THR A   8;VAL A  97;VAL A 102","None","1.07A","3me6A-3mjzA:undetectable","3me6A-3mjzA:14.78"],["3ME6_C_CGEC501_1","CYTOCHROME P450 2B4","3mjz","FG41 MALONATE SEMIALDEHYDE DECARBOXYLASE","coryneform bacterium",5,"VAL A  23;ILE A  68;THR A   8;VAL A  97;VAL A 102","None","1.13A","3me6C-3mjzA:undetectable","3me6C-3mjzA:14.78"],["3ME6_D_CGED501_1","CYTOCHROME P450 2B4","3mjz","FG41 MALONATE SEMIALDEHYDE DECARBOXYLASE","coryneform bacterium",5,"VAL A  23;ILE A  68;THR A   8;VAL A  97;VAL A 102","None","1.07A","3me6D-3mjzA:undetectable","3me6D-3mjzA:14.78"],["4O2B_B_LOCB503_2","TUBULIN BETA-2B CHAIN","3mjz","FG41 MALONATE SEMIALDEHYDE DECARBOXYLASE","coryneform bacterium",5,"ALA A  87;LEU A  27;THR A  72;ILE A  68;ILE A   3","None","1.12A","4o2bB-3mjzA:undetectable","4o2bB-3mjzA:16.43"]]