SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mk3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Salmonella
enterica) 		5 / 12 GLY A 130
GLY A 134
ALA A 138
ASP A  32
SER A  29
 None
 1.08A 1ri4A-3mk3A:
undetectable		 1ri4A-3mk3A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Salmonella
enterica) 		5 / 12 LEU A  60
ALA A  78
ALA A  68
VAL A 104
ALA A 105
 None
 1.19A 1sa1C-3mk3A:
undetectable
1sa1D-3mk3A:
undetectable		 1sa1C-3mk3A:
15.18
1sa1D-3mk3A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Salmonella
enterica) 		5 / 12 VAL A  76
ALA A 141
ALA A 140
LEU A  38
ALA A  37
 None
 0.92A 3fc6C-3mk3A:
undetectable		 3fc6C-3mk3A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Salmonella
enterica) 		5 / 9 LEU A 145
THR A 143
GLY A 115
ALA A  78
THR A  64
 None
 1.38A 3jusB-3mk3A:
undetectable		 3jusB-3mk3A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Salmonella
enterica) 		5 / 12 ASN A  27
ILE A  83
THR A  81
THR A 119
ILE A 126
 None
 1.24A 3kpbA-3mk3A:
undetectable		 3kpbA-3mk3A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Salmonella
enterica) 		4 / 8 THR A  18
ALA A  16
THR A  50
VAL A  52
 None
 0.54A 4ik7B-3mk3A:
undetectable		 4ik7B-3mk3A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Salmonella
enterica) 		5 / 10 ALA A 140
ILE A  17
ILE A  41
VAL A  15
VAL A  77
 None
 1.10A 4j5jB-3mk3A:
undetectable		 4j5jB-3mk3A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Salmonella
enterica) 		4 / 8 ILE A  49
ALA A  75
VAL A  77
VAL A  44
 None
 0.73A 5ecnD-3mk3A:
undetectable		 5ecnD-3mk3A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Salmonella
enterica) 		3 / 3 ASP A  47
ASN A  48
ASP A  12
 None
 0.81A 5vopA-3mk3A:
undetectable		 5vopA-3mk3A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Salmonella
enterica) 		3 / 3 ASP A  47
ASN A  48
ASP A  12
 None
 0.89A 5vopB-3mk3A:
undetectable		 5vopB-3mk3A:
20.62