SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mkl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3mkl HTH-TYPE
TRANSCRIPTIONAL
REGULATOR GADX
(Escherichia
coli) 		4 / 4 ASN A 142
SER A 171
LEU A 174
THR A 145
 None
 1.17A 4an2A-3mklA:
undetectable		 4an2A-3mklA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3mkl HTH-TYPE
TRANSCRIPTIONAL
REGULATOR GADX
(Escherichia
coli) 		3 / 3 LEU A 201
PHE A 224
ILE A 202
 None
 0.72A 5dzk1-3mklA:
undetectable
5dzkF-3mklA:
undetectable
5dzkM-3mklA:
undetectable		 5dzk1-3mklA:
5.88
5dzkF-3mklA:
19.09
5dzkM-3mklA:
17.16