SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mky'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3mky PROTEIN SOPB
(Escherichia
coli) 		5 / 9 GLY B 221
SER B 220
LEU B 224
PHE B 210
LEU B 261
 None
 1.23A 1y7iA-3mkyB:
undetectable		 1y7iA-3mkyB:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3mky PROTEIN SOPB
(Escherichia
coli) 		5 / 10 THR B 199
VAL B 206
VAL B 207
ILE B 258
VAL B 257
 None
 1.12A 2qboA-3mkyB:
undetectable		 2qboA-3mkyB:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3mky PROTEIN SOPB
(Escherichia
coli) 		5 / 12 HIS B 243
LEU B 242
ALA B 239
PRO B 203
LEU B 202
 None
None
None
SO4  B 324 (-3.8A)
SO4  B 835 (-4.5A)
 1.20A 5nd4B-3mkyB:
undetectable		 5nd4B-3mkyB:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 3mky PROTEIN SOPB
(Escherichia
coli) 		5 / 12 ARG B 166
SER B 220
GLY B 221
THR B 199
GLN B 165
 None
 1.40A 5oj0A-3mkyB:
undetectable		 5oj0A-3mkyB:
13.68