SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mkz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3mkz PROTEIN SOPB
(Escherichia
coli) 		5 / 9 GLY A 221
SER A 220
LEU A 224
PHE A 210
LEU A 261
 None
 1.29A 1y7iA-3mkzA:
undetectable		 1y7iA-3mkzA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 3mkz PROTEIN SOPB
(Escherichia
coli) 		4 / 6 ALA A 185
ASP A 184
GLU A 186
ARG A 166
 None
CA  A   1 (-4.6A)
None
None
 1.38A 2ouzA-3mkzA:
undetectable		 2ouzA-3mkzA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3mkz PROTEIN SOPB
(Escherichia
coli) 		5 / 10 THR A 199
VAL A 206
VAL A 207
ILE A 258
VAL A 257
 None
 1.05A 2qboA-3mkzA:
undetectable		 2qboA-3mkzA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3mkz PROTEIN SOPB
(Escherichia
coli) 		4 / 6 ILE A 179
LEU A 171
ARG A 195
THR A 199
 None
 1.18A 3wg7A-3mkzA:
undetectable
3wg7J-3mkzA:
undetectable		 3wg7A-3mkzA:
12.22
3wg7J-3mkzA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3mkz PROTEIN SOPB
(Escherichia
coli) 		4 / 6 ILE A 179
LEU A 171
ARG A 195
THR A 199
 None
 1.08A 6nmfN-3mkzA:
undetectable
6nmfW-3mkzA:
undetectable		 6nmfN-3mkzA:
12.22
6nmfW-3mkzA:
18.75