SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ml4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		4 / 6 ILE A 104
ARG A  27
THR A  58
LEU A  59
 None
 0.97A 3ag1N-3ml4A:
undetectable
3ag1W-3ml4A:
undetectable		 3ag1N-3ml4A:
18.97
3ag1W-3ml4A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		4 / 6 VAL A 111
GLY A 150
ARG A 142
LEU A 124
 None
 1.10A 3bjwE-3ml4A:
undetectable		 3bjwE-3ml4A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		5 / 12 ASN A 135
GLY A 109
ASP A 136
GLY A 202
SER A 204
 None
 1.23A 3k13A-3ml4A:
undetectable		 3k13A-3ml4A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		5 / 12 GLU A 110
ASN A 135
GLY A 109
ASP A 136
GLY A 202
 None
 1.29A 3k13A-3ml4A:
undetectable		 3k13A-3ml4A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		5 / 12 ASN A 135
GLY A 109
ASP A 136
GLY A 202
SER A 204
 None
 1.24A 3k13B-3ml4A:
undetectable		 3k13B-3ml4A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		5 / 12 ASN A 135
GLY A 109
ASP A 136
GLY A 202
SER A 204
 None
 1.23A 3k13C-3ml4A:
undetectable		 3k13C-3ml4A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		4 / 6 SER A  48
GLY A   9
GLU A   8
ASP A  92
 None
 1.04A 4uckB-3ml4A:
undetectable		 4uckB-3ml4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		4 / 6 ILE A 104
ILE A 199
HIS A 132
PHE A 194
 None
 0.99A 5vkqA-3ml4A:
undetectable
5vkqB-3ml4A:
undetectable		 5vkqA-3ml4A:
8.10
5vkqB-3ml4A:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		4 / 6 ILE A 104
ILE A 199
HIS A 132
PHE A 194
 None
 0.99A 5vkqB-3ml4A:
undetectable
5vkqC-3ml4A:
undetectable		 5vkqB-3ml4A:
8.10
5vkqC-3ml4A:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		4 / 6 ILE A 104
ILE A 199
HIS A 132
PHE A 194
 None
 1.00A 5vkqC-3ml4A:
undetectable
5vkqD-3ml4A:
undetectable		 5vkqC-3ml4A:
8.10
5vkqD-3ml4A:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		4 / 6 PHE A 194
ILE A 104
ILE A 199
HIS A 132
 None
 0.96A 5vkqA-3ml4A:
undetectable
5vkqD-3ml4A:
undetectable		 5vkqA-3ml4A:
8.10
5vkqD-3ml4A:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		4 / 6 ILE A 104
ARG A  27
THR A  58
LEU A  59
 None
 1.02A 5z86N-3ml4A:
undetectable
5z86W-3ml4A:
undetectable		 5z86N-3ml4A:
18.97
5z86W-3ml4A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ml4 PROTEIN DOK-7
(Mus
musculus) 		4 / 6 ILE A 104
ARG A  27
THR A  58
LEU A  59
 None
 0.98A 5zcoN-3ml4A:
undetectable
5zcoW-3ml4A:
undetectable		 5zcoN-3ml4A:
18.97
5zcoW-3ml4A:
16.43