SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ml5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 7 HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.17A 1am6A-3ml5A:
42.5		 1am6A-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 7 HIS A 119
HIS A  94
HIS A  96
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.5A)
 1.02A 1am6A-3ml5A:
42.5		 1am6A-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 8 HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.23A 1azmA-3ml5A:
40.2		 1azmA-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 8 PHE A 131
HIS A  96
THR A 199
TRP A 209
 AZM  A 264 (-4.4A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
None
 0.75A 1azmA-3ml5A:
40.2		 1azmA-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 8 HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.21A 1bzmA-3ml5A:
40.1		 1bzmA-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 8 PHE A 131
HIS A  96
THR A 199
TRP A 209
 AZM  A 264 (-4.4A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
None
 0.80A 1bzmA-3ml5A:
40.1		 1bzmA-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.09A 1cilA-3ml5A:
42.6		 1cilA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.23A 1cilA-3ml5A:
42.6		 1cilA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.37A 1cilA-3ml5A:
42.6		 1cilA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 HIS A   2
GLN A  92
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
AZM  A 264 (-4.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.19A 1cilA-3ml5A:
42.6		 1cilA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 HIS A  64
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.39A 1cilA-3ml5A:
42.6		 1cilA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A  96
HIS A 119
SER A 204
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
None
None
 1.23A 1dmyA-3ml5A:
38.0		 1dmyA-3ml5A:
46.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 141
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
None
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.54A 1dmyA-3ml5A:
38.0		 1dmyA-3ml5A:
46.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A 119
HIS A  94
HIS A  96
TYR A 194
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
None
AZM  A 264 (-3.5A)
 1.16A 1dmyA-3ml5A:
38.0		 1dmyA-3ml5A:
46.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.16A 1dmyB-3ml5A:
38.0		 1dmyB-3ml5A:
46.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.38A 1dmyB-3ml5A:
38.0		 1dmyB-3ml5A:
46.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.46A 1dmyB-3ml5A:
38.0		 1dmyB-3ml5A:
46.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 HIS A 119
HIS A  94
HIS A  96
TYR A 194
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
None
AZM  A 264 (-3.5A)
 1.13A 1dmyB-3ml5A:
38.0		 1dmyB-3ml5A:
46.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 LEU A 148
VAL A 146
SER A  65
HIS A 154
LEU A 160
 None
 1.30A 1ie9A-3ml5A:
undetectable		 1ie9A-3ml5A:
18.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 9 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.88A 1jd0A-3ml5A:
36.7		 1jd0A-3ml5A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.40A 1jd0A-3ml5A:
36.7		 1jd0A-3ml5A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.86A 1jd0B-3ml5A:
36.5		 1jd0B-3ml5A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.06A 1jd0B-3ml5A:
36.5		 1jd0B-3ml5A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.48A 1jd0B-3ml5A:
36.5		 1jd0B-3ml5A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.37A 1jd0B-3ml5A:
36.5		 1jd0B-3ml5A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.98A 1jd0B-3ml5A:
36.5		 1jd0B-3ml5A:
38.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 LEU A 160
THR A  77
LEU A  90
LEU A 118
LEU A 120
 None
 1.11A 1mx1C-3ml5A:
undetectable		 1mx1C-3ml5A:
19.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 ASN A  62
HIS A  96
LEU A 198
THR A 199
PRO A 202
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.99A 1oq5A-3ml5A:
43.3		 1oq5A-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
PRO A 202
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
None
 0.31A 1oq5A-3ml5A:
43.3		 1oq5A-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 200
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.48A 1oq5A-3ml5A:
43.3		 1oq5A-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
PRO A 202
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 1.47A 1oq5A-3ml5A:
43.3		 1oq5A-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.01A 1rj6A-3ml5A:
37.3		 1rj6A-3ml5A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.37A 1rj6A-3ml5A:
37.3		 1rj6A-3ml5A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.42A 1rj6A-3ml5A:
37.3		 1rj6A-3ml5A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.01A 1rj6B-3ml5A:
36.9		 1rj6B-3ml5A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.37A 1rj6B-3ml5A:
36.9		 1rj6B-3ml5A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  94
HIS A  96
HIS A 119
LEU A  90
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
None
None
 1.40A 1rj6B-3ml5A:
36.9		 1rj6B-3ml5A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.42A 1rj6B-3ml5A:
36.9		 1rj6B-3ml5A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A 119
VAL A 121
PHE A 131
VAL A 143
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.30A 1ydaA-3ml5A:
42.1		 1ydaA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
VAL A 121
PHE A 131
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
 1.13A 1ydaA-3ml5A:
42.1		 1ydaA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.06A 1ydbA-3ml5A:
42.3		 1ydbA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 131
VAL A 143
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.24A 1ydbA-3ml5A:
42.3		 1ydbA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
 1.21A 1ydbA-3ml5A:
42.3		 1ydbA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.08A 1yddA-3ml5A:
42.6		 1yddA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 131
VAL A 143
THR A 199
THR A 200
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.28A 1yddA-3ml5A:
42.6		 1yddA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
 1.23A 1yddA-3ml5A:
42.6		 1yddA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.07A 1z9yA-3ml5A:
43.0		 1z9yA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.23A 1z9yA-3ml5A:
43.0		 1z9yA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.38A 1z9yA-3ml5A:
43.0		 1z9yA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.43A 1z9yA-3ml5A:
43.0		 1z9yA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 ASN A  62
GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.27A 1zgfA-3ml5A:
43.1		 1zgfA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 ASN A  62
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.01A 1zgfA-3ml5A:
43.1		 1zgfA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.02A 1zgfA-3ml5A:
43.1		 1zgfA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.26A 1zgfA-3ml5A:
43.1		 1zgfA-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.87A 1zsbA-3ml5A:
43.2		 1zsbA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.04A 1zsbA-3ml5A:
43.2		 1zsbA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.29A 1zsbA-3ml5A:
43.2		 1zsbA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.41A 1zsbA-3ml5A:
43.2		 1zsbA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.95A 1zsbA-3ml5A:
43.2		 1zsbA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
None
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.21A 2aw1A-3ml5A:
43.0		 2aw1A-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  96
LEU A 141
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
None
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.27A 2aw1A-3ml5A:
43.0		 2aw1A-3ml5A:
55.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 6 ASN A  62
GLN A  67
THR A 200
PRO A 202
 None
None
AZM  A 264 (-3.5A)
None
 1.11A 2ez7A-3ml5A:
42.8		 2ez7A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 6 TRP A   5
GLN A  67
THR A 200
PRO A 202
 None
None
AZM  A 264 (-3.5A)
None
 1.13A 2ez7A-3ml5A:
42.8		 2ez7A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 6 TRP A   5
GLN A  92
THR A 200
PRO A 202
 None
AZM  A 264 (-4.1A)
AZM  A 264 (-3.5A)
None
 0.29A 2ez7A-3ml5A:
42.8		 2ez7A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 6 TRP A   5
HIS A  64
THR A 200
PRO A 202
 None
None
AZM  A 264 (-3.5A)
None
 1.15A 2ez7A-3ml5A:
42.8		 2ez7A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.20A 2gehA-3ml5A:
43.1		 2gehA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 GLN A  67
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.88A 2h4nA-3ml5A:
43.1		 2h4nA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  96
HIS A 119
VAL A 121
PHE A 131
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.43A 2h4nA-3ml5A:
43.1		 2h4nA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 GLN A  92
HIS A  96
VAL A 121
PHE A 131
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
 1.42A 2h4nA-3ml5A:
43.1		 2h4nA-3ml5A:
55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 6 ASN A  62
HIS A  64
GLN A  92
THR A 200
 None
None
AZM  A 264 (-4.1A)
AZM  A 264 (-3.5A)
 0.44A 2hkkA-3ml5A:
43.1		 2hkkA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 0.28A 2it4A-3ml5A:
40.5		 2it4A-3ml5A:
51.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 8 HIS A  96
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 0.86A 2it4A-3ml5A:
40.5		 2it4A-3ml5A:
51.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 LEU A  90
TYR A  51
PHE A  70
VAL A  68
PHE A 179
 None
 1.37A 2jj8B-3ml5A:
undetectable		 2jj8B-3ml5A:
21.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 ASN A  62
GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.21A 2pouA-3ml5A:
43.1		 2pouA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 ASN A  62
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.02A 2pouA-3ml5A:
43.1		 2pouA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.07A 2pouA-3ml5A:
43.1		 2pouA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.38A 2pouA-3ml5A:
43.1		 2pouA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.37A 2pouA-3ml5A:
43.1		 2pouA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.34A 3bl1A-3ml5A:
42.8		 3bl1A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.06A 3bl1A-3ml5A:
42.8		 3bl1A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.01A 3bl1A-3ml5A:
42.8		 3bl1A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.37A 3bl1A-3ml5A:
42.8		 3bl1A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 HIS A  64
GLN A  67
VAL A 121
THR A 199
THR A 200
 None
None
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.29A 3bl1A-3ml5A:
42.8		 3bl1A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.97A 3bl1A-3ml5A:
42.8		 3bl1A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 131
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.24A 3cajA-3ml5A:
43.2		 3cajA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  94
HIS A 119
THR A 199
PRO A 201
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
None
None
 1.28A 3cajA-3ml5A:
43.2		 3cajA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 10 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 1.47A 3cajA-3ml5A:
43.2		 3cajA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
 ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.86A 3cajA-3ml5A:
43.2		 3cajA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.39A 3cajA-3ml5A:
43.2		 3cajA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
 0.91A 3czvA-3ml5A:
42.7
3czvB-3ml5A:
42.6		 3czvA-3ml5A:
52.99
3czvB-3ml5A:
52.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.48A 3czvA-3ml5A:
42.7
3czvB-3ml5A:
42.6		 3czvA-3ml5A:
52.99
3czvB-3ml5A:
52.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
 0.99A 3czvB-3ml5A:
42.6		 3czvB-3ml5A:
52.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.41A 3czvB-3ml5A:
42.6		 3czvB-3ml5A:
52.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.05A 3dazA-3ml5A:
43.0		 3dazA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 131
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.27A 3dazA-3ml5A:
43.0		 3dazA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.42A 3dazA-3ml5A:
43.0		 3dazA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.39A 3dazA-3ml5A:
43.0		 3dazA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.90A 3dc3A-3ml5A:
43.1		 3dc3A-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.17A 3dc3A-3ml5A:
43.1		 3dc3A-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.30A 3dc3A-3ml5A:
43.1		 3dc3A-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.41A 3dc3A-3ml5A:
43.1		 3dc3A-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.93A 3dcsA-3ml5A:
43.0		 3dcsA-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 131
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.35A 3dcsA-3ml5A:
43.0		 3dcsA-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.45A 3dcsA-3ml5A:
43.0		 3dcsA-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.36A 3dcsA-3ml5A:
43.0		 3dcsA-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.24A 3dcwA-3ml5A:
43.0		 3dcwA-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 10 HIS A  94
HIS A 119
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 1.48A 3dcwA-3ml5A:
43.0		 3dcwA-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A  94
HIS A 119
VAL A 143
THR A 199
PRO A 201
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
None
None
 1.28A 3dcwA-3ml5A:
43.0		 3dcwA-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.01A 3dcwA-3ml5A:
43.0		 3dcwA-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
PRO A 202
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.42A 3dcwA-3ml5A:
43.0		 3dcwA-3ml5A:
56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.24A 3dd0A-3ml5A:
42.9		 3dd0A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.00A 3dd0A-3ml5A:
42.9		 3dd0A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
PRO A 202
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.41A 3dd0A-3ml5A:
42.9		 3dd0A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 ASN A  62
GLN A  67
HIS A  96
VAL A 121
THR A 200
PRO A 202
 None
None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.5A)
None
 1.25A 3f4xA-3ml5A:
42.6		 3f4xA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.33A 3f4xA-3ml5A:
42.6		 3f4xA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 ASN A  62
HIS A  94
VAL A 143
THR A 199
PRO A 201
TRP A 209
 None
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
None
None
 1.32A 3f4xA-3ml5A:
42.6		 3f4xA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 ASN A  62
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.09A 3f4xA-3ml5A:
42.6		 3f4xA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  96
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 1.28A 3f4xA-3ml5A:
42.6		 3f4xA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 12 ASN A  62
HIS A  64
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.44A 3fw3A-3ml5A:
32.7		 3fw3A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 HIS A   2
GLN A  92
VAL A 121
VAL A 143
LEU A 198
THR A 200
TRP A 209
 None
AZM  A 264 (-4.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.47A 3fw3A-3ml5A:
32.7		 3fw3A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  64
GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.00A 3fw3A-3ml5A:
32.7		 3fw3A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.30A 3fw3B-3ml5A:
32.7		 3fw3B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.00A 3fw3B-3ml5A:
32.7		 3fw3B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 ASN A  62
GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.30A 3hkuA-3ml5A:
43.3		 3hkuA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 200
TRP A 209
 None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.37A 3hkuA-3ml5A:
43.3		 3hkuA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.13A 3hkuA-3ml5A:
43.3		 3hkuA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.38A 3hkuA-3ml5A:
43.3		 3hkuA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		3 / 3 GLU A 106
HIS A 119
THR A 199
 ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
 0.11A 3hkuA-3ml5A:
43.3		 3hkuA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.06A 3hs4A-3ml5A:
43.4		 3hs4A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.22A 3hs4A-3ml5A:
43.4		 3hs4A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.24A 3hs4A-3ml5A:
43.4		 3hs4A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.38A 3hs4A-3ml5A:
43.4		 3hs4A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.04A 3iaiA-3ml5A:
34.7		 3iaiA-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.23A 3iaiA-3ml5A:
34.7		 3iaiA-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.91A 3iaiA-3ml5A:
34.7		 3iaiA-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.96A 3iaiB-3ml5A:
34.8		 3iaiB-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.23A 3iaiB-3ml5A:
34.8		 3iaiB-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.91A 3iaiB-3ml5A:
34.8		 3iaiB-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.97A 3iaiC-3ml5A:
34.7		 3iaiC-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.21A 3iaiC-3ml5A:
34.7		 3iaiC-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.91A 3iaiC-3ml5A:
34.7		 3iaiC-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.97A 3iaiD-3ml5A:
34.8		 3iaiD-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.23A 3iaiD-3ml5A:
34.8		 3iaiD-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.89A 3iaiD-3ml5A:
34.8		 3iaiD-3ml5A:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A 119
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.35A 3kwaA-3ml5A:
42.6		 3kwaA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.32A 3kwaA-3ml5A:
42.6		 3kwaA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
PRO A 201
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
None
 1.34A 3kwaA-3ml5A:
42.6		 3kwaA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 1.46A 3kwaA-3ml5A:
42.6		 3kwaA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
 AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.87A 3kwaA-3ml5A:
42.6		 3kwaA-3ml5A:
55.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 ILE A  22
PHE A 131
ALA A 142
LEU A 141
ALA A 134
 None
AZM  A 264 (-4.4A)
None
None
None
 0.98A 3lw5B-3ml5A:
undetectable		 3lw5B-3ml5A:
18.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 0.87A 3lxeA-3ml5A:
40.7		 3lxeA-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.16A 3lxeA-3ml5A:
40.7		 3lxeA-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 SER A  65
GLN A  92
HIS A  94
HIS A  96
VAL A 143
LEU A 198
THR A 199
TRP A 209
 None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.56A 3lxeA-3ml5A:
40.7		 3lxeA-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 SER A  65
PHE A 131
HIS A  96
VAL A 143
THR A 199
TRP A 209
 None
AZM  A 264 (-4.4A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
None
 1.04A 3lxeA-3ml5A:
40.7		 3lxeA-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 0.87A 3lxeB-3ml5A:
40.7		 3lxeB-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.16A 3lxeB-3ml5A:
40.7		 3lxeB-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 SER A  65
GLN A  92
HIS A  94
HIS A  96
VAL A 143
LEU A 198
THR A 199
TRP A 209
 None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.58A 3lxeB-3ml5A:
40.7		 3lxeB-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 SER A  65
PHE A 131
GLN A  92
HIS A  96
VAL A 143
THR A 199
TRP A 209
 None
AZM  A 264 (-4.4A)
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
None
 1.20A 3lxeB-3ml5A:
40.7		 3lxeB-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
ALA A 135
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
None
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.54A 3mdzA-3ml5A:
43.8		 3mdzA-3ml5A:
95.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.88A 3mdzA-3ml5A:
43.8		 3mdzA-3ml5A:
95.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 1.46A 3mdzA-3ml5A:
43.8		 3mdzA-3ml5A:
95.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.39A 3mdzA-3ml5A:
43.8		 3mdzA-3ml5A:
95.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.07A 3v2jA-3ml5A:
43.1		 3v2jA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.24A 3v2jA-3ml5A:
43.1		 3v2jA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.41A 3v2jA-3ml5A:
43.1		 3v2jA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.93A 3v2jA-3ml5A:
43.1		 3v2jA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.04A 3v2mA-3ml5A:
43.3		 3v2mA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
PHE A 131
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.20A 3v2mA-3ml5A:
43.3		 3v2mA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.49A 3v2mA-3ml5A:
43.3		 3v2mA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.90A 3v2mA-3ml5A:
43.3		 3v2mA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.39A 3v2mA-3ml5A:
43.3		 3v2mA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 8 GLN A  67
HIS A  94
HIS A  96
THR A 199
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
 0.89A 3w6hA-3ml5A:
40.5		 3w6hA-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 8 GLN A  92
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.38A 3w6hA-3ml5A:
40.5		 3w6hA-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 GLN A  67
HIS A  94
HIS A  96
GLU A 106
THR A 199
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
 0.83A 3w6hB-3ml5A:
40.5		 3w6hB-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
LEU A 198
THR A 199
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.39A 3w6hB-3ml5A:
40.5		 3w6hB-3ml5A:
50.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.95A 3zncA-3ml5A:
31.7		 3zncA-3ml5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.47A 3zncA-3ml5A:
31.7		 3zncA-3ml5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  92
HIS A  94
VAL A 121
PHE A 131
THR A 200
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.5A)
 1.40A 3zncA-3ml5A:
31.7		 3zncA-3ml5A:
33.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 7 LEU A 198
GLU A 117
HIS A 119
HIS A  94
 AZM  A 264 (-3.4A)
None
ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
 1.20A 4aq7A-3ml5A:
undetectable		 4aq7A-3ml5A:
15.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.01A 4coqA-3ml5A:
31.4		 4coqA-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.21A 4coqA-3ml5A:
31.4		 4coqA-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.19A 4coqA-3ml5A:
31.4		 4coqA-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.96A 4coqA-3ml5A:
31.4		 4coqA-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.21A 4coqB-3ml5A:
31.4		 4coqB-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A  94
THR A 200
THR A 199
TRP A   5
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.5A)
AZM  A 264 (-3.4A)
None
 1.38A 4coqB-3ml5A:
31.4		 4coqB-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.98A 4coqB-3ml5A:
31.4		 4coqB-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.42A 4coqB-3ml5A:
31.4		 4coqB-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 GLN A  92
VAL A 121
PHE A 131
LEU A 141
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
None
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.24A 4e3hA-3ml5A:
43.2		 4e3hA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
VAL A 121
PHE A 131
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
VAL A 207
TRP A 209
 AZM  A 264 (-4.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
None
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.38A 4e3hA-3ml5A:
43.2		 4e3hA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.92A 4g0cA-3ml5A:
42.9		 4g0cA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
GLU A 117
VAL A 121
PHE A 131
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
None
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
 1.25A 4g0cA-3ml5A:
42.9		 4g0cA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
PHE A 131
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.23A 4g0cA-3ml5A:
42.9		 4g0cA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.40A 4g0cA-3ml5A:
42.9		 4g0cA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.95A 4g0cA-3ml5A:
42.9		 4g0cA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.97A 4g7aA-3ml5A:
29.9		 4g7aA-3ml5A:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.11A 4g7aA-3ml5A:
29.9		 4g7aA-3ml5A:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.44A 4g7aA-3ml5A:
29.9		 4g7aA-3ml5A:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.21A 4g7aA-3ml5A:
29.9		 4g7aA-3ml5A:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.48A 4g7aA-3ml5A:
29.9		 4g7aA-3ml5A:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.97A 4g7aB-3ml5A:
29.9		 4g7aB-3ml5A:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.14A 4g7aB-3ml5A:
29.9		 4g7aB-3ml5A:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.45A 4g7aB-3ml5A:
29.9		 4g7aB-3ml5A:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.18A 4g7aB-3ml5A:
29.9		 4g7aB-3ml5A:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.41A 4g7aB-3ml5A:
29.9		 4g7aB-3ml5A:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.08A 4k0sA-3ml5A:
43.4		 4k0sA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.18A 4k0sA-3ml5A:
43.4		 4k0sA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 263 ( 3.2A)
None
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.27A 4k0sA-3ml5A:
43.4		 4k0sA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.94A 4k0sA-3ml5A:
43.4		 4k0sA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
THR A 200
PRO A 202
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.5A)
None
 1.05A 4k0zA-3ml5A:
43.1		 4k0zA-3ml5A:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.17A 4k0zA-3ml5A:
43.1		 4k0zA-3ml5A:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
None
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.26A 4k13A-3ml5A:
43.5		 4k13A-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.48A 4k13A-3ml5A:
43.5		 4k13A-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  96
LEU A 141
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
None
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.26A 4k13A-3ml5A:
43.5		 4k13A-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.07A 4lu3A-3ml5A:
36.8		 4lu3A-3ml5A:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.30A 4lu3A-3ml5A:
36.8		 4lu3A-3ml5A:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.90A 4lu3A-3ml5A:
36.8		 4lu3A-3ml5A:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.42A 4m2rA-3ml5A:
43.2		 4m2rA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 ASN A  62
HIS A  94
VAL A 143
THR A 199
PRO A 201
TRP A 209
 None
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
None
None
 1.29A 4m2rA-3ml5A:
43.2		 4m2rA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.22A 4m2rA-3ml5A:
43.2		 4m2rA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.37A 4m2rA-3ml5A:
43.2		 4m2rA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 4 HIS A  64
GLU A 106
HIS A 119
LEU A 141
 None
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
None
 0.35A 4m2rA-3ml5A:
43.2		 4m2rA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.23A 4m2uA-3ml5A:
43.0		 4m2uA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.38A 4m2uA-3ml5A:
43.0		 4m2uA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 HIS A   2
GLN A  92
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
AZM  A 264 (-4.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.21A 4m2uA-3ml5A:
43.0		 4m2uA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 TRP A   5
GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.13A 4m2uA-3ml5A:
43.0		 4m2uA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 TRP A   5
HIS A  64
GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.42A 4m2uA-3ml5A:
43.0		 4m2uA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 TRP A   5
HIS A  64
HIS A  94
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.37A 4m2uA-3ml5A:
43.0		 4m2uA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 TRP A   5
HIS A  64
HIS A  96
VAL A 143
LEU A 198
THR A 200
 None
None
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.13A 4m2uA-3ml5A:
43.0		 4m2uA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 TRP A  16
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 200
TRP A 209
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.39A 4m2uA-3ml5A:
43.0		 4m2uA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.20A 4m2vA-3ml5A:
43.1		 4m2vA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
GLY A 132
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
None
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.40A 4m2vA-3ml5A:
43.1		 4m2vA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
GLY A 132
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
None
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.30A 4m2vA-3ml5A:
43.1		 4m2vA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.20A 4m2wA-3ml5A:
43.1		 4m2wA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
None
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.32A 4m2wA-3ml5A:
43.1		 4m2wA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  96
LEU A 141
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
None
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.32A 4m2wA-3ml5A:
43.1		 4m2wA-3ml5A:
56.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 8 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.09A 4n16A-3ml5A:
43.5		 4n16A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 8 GLN A  92
HIS A  94
HIS A  96
HIS A 119
PHE A 131
THR A 199
THR A 200
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.36A 4n16A-3ml5A:
43.5		 4n16A-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 8 GLN A  92
HIS A  94
HIS A  96
PHE A 131
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
 1.24A 4n16A-3ml5A:
43.5		 4n16A-3ml5A:
55.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 4 ASN A 243
GLY A  98
ASP A 110
ASP A 102
 None
 1.10A 4n49A-3ml5A:
undetectable		 4n49A-3ml5A:
21.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.08A 4pxxA-3ml5A:
43.2		 4pxxA-3ml5A:
55.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
PHE A 131
THR A 199
THR A 200
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.32A 4pxxA-3ml5A:
43.2		 4pxxA-3ml5A:
55.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 GLN A  92
HIS A  94
HIS A  96
PHE A 131
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
 1.22A 4pxxA-3ml5A:
43.2		 4pxxA-3ml5A:
55.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
VAL A 143
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
None
 0.34A 4twlA-3ml5A:
28.2		 4twlA-3ml5A:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
VAL A 143
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
None
 0.30A 4twlB-3ml5A:
28.0		 4twlB-3ml5A:
28.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.16A 4uovA-3ml5A:
31.2		 4uovA-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.48A 4uovA-3ml5A:
31.2		 4uovA-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.22A 4uovA-3ml5A:
31.2		 4uovA-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.14A 4uovB-3ml5A:
31.4		 4uovB-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.46A 4uovB-3ml5A:
31.4		 4uovB-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.20A 4uovB-3ml5A:
31.4		 4uovB-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.06A 4uovC-3ml5A:
31.1		 4uovC-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.48A 4uovC-3ml5A:
31.1		 4uovC-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.22A 4uovC-3ml5A:
31.1		 4uovC-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.96A 4uovC-3ml5A:
31.1		 4uovC-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.16A 4uovD-3ml5A:
31.2		 4uovD-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.48A 4uovD-3ml5A:
31.2		 4uovD-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
GLU A 117
VAL A 121
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
None
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
 1.21A 4uovD-3ml5A:
31.2		 4uovD-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.22A 4uovD-3ml5A:
31.2		 4uovD-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.05A 4uovE-3ml5A:
31.2		 4uovE-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.49A 4uovE-3ml5A:
31.2		 4uovE-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.20A 4uovE-3ml5A:
31.2		 4uovE-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.96A 4uovE-3ml5A:
31.2		 4uovE-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.15A 4uovF-3ml5A:
31.3		 4uovF-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.47A 4uovF-3ml5A:
31.3		 4uovF-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.21A 4uovF-3ml5A:
31.3		 4uovF-3ml5A:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.98A 4x5sA-3ml5A:
29.6		 4x5sA-3ml5A:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.16A 4x5sA-3ml5A:
29.6		 4x5sA-3ml5A:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.47A 4x5sA-3ml5A:
29.6		 4x5sA-3ml5A:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.21A 4x5sA-3ml5A:
29.6		 4x5sA-3ml5A:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.39A 4x5sA-3ml5A:
29.6		 4x5sA-3ml5A:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.98A 4x5sB-3ml5A:
29.7		 4x5sB-3ml5A:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.15A 4x5sB-3ml5A:
29.7		 4x5sB-3ml5A:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.48A 4x5sB-3ml5A:
29.7		 4x5sB-3ml5A:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.20A 4x5sB-3ml5A:
29.7		 4x5sB-3ml5A:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.39A 4x5sB-3ml5A:
29.7		 4x5sB-3ml5A:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.5A)
 0.93A 4xiwA-3ml5A:
26.0
4xiwH-3ml5A:
25.6		 4xiwA-3ml5A:
34.91
4xiwH-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.41A 4xiwA-3ml5A:
26.0
4xiwH-3ml5A:
25.6		 4xiwA-3ml5A:
34.91
4xiwH-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.29A 4xiwA-3ml5A:
26.0
4xiwH-3ml5A:
25.6		 4xiwA-3ml5A:
34.91
4xiwH-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.44A 4xiwA-3ml5A:
26.0
4xiwH-3ml5A:
25.6		 4xiwA-3ml5A:
34.91
4xiwH-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.08A 4xiwB-3ml5A:
25.9
4xiwE-3ml5A:
25.8		 4xiwB-3ml5A:
34.91
4xiwE-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.29A 4xiwB-3ml5A:
25.9
4xiwE-3ml5A:
25.8		 4xiwB-3ml5A:
34.91
4xiwE-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.10A 4xiwC-3ml5A:
25.8		 4xiwC-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.21A 4xiwC-3ml5A:
25.8		 4xiwC-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.34A 4xiwC-3ml5A:
25.8		 4xiwC-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.32A 4xiwC-3ml5A:
25.8		 4xiwC-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.42A 4xiwC-3ml5A:
25.8		 4xiwC-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.08A 4xiwD-3ml5A:
25.9		 4xiwD-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.16A 4xiwD-3ml5A:
25.9		 4xiwD-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.39A 4xiwD-3ml5A:
25.9		 4xiwD-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.23A 4xiwD-3ml5A:
25.9		 4xiwD-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.41A 4xiwE-3ml5A:
25.8		 4xiwE-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.22A 4xiwE-3ml5A:
25.8		 4xiwE-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.95A 4xiwE-3ml5A:
25.8		 4xiwE-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.43A 4xiwE-3ml5A:
25.8		 4xiwE-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.05A 4xiwF-3ml5A:
25.7		 4xiwF-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.18A 4xiwF-3ml5A:
25.7		 4xiwF-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.45A 4xiwF-3ml5A:
25.7		 4xiwF-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.23A 4xiwF-3ml5A:
25.7		 4xiwF-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.44A 4xiwF-3ml5A:
25.7		 4xiwF-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.14A 4xiwG-3ml5A:
25.6		 4xiwG-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  92
GLU A 117
VAL A 121
LEU A 141
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
AZM  A 264 (-4.7A)
None
AZM  A 264 ( 4.9A)
None
 1.47A 4xiwG-3ml5A:
25.6		 4xiwG-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
None
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.46A 4xiwG-3ml5A:
25.6		 4xiwG-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 HIS A  96
GLU A 106
LEU A 141
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
None
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.41A 4xiwG-3ml5A:
25.6		 4xiwG-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.07A 4xiwH-3ml5A:
25.6		 4xiwH-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.40A 4xiwH-3ml5A:
25.6		 4xiwH-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.25A 4xiwH-3ml5A:
25.6		 4xiwH-3ml5A:
34.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.00A 4xiwH-3ml5A:
25.6		 4xiwH-3ml5A:
34.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.30A 4ygfA-3ml5A:
26.2		 4ygfA-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.37A 4ygfB-3ml5A:
25.8		 4ygfB-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A 119
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 1.45A 4ygfB-3ml5A:
25.8		 4ygfB-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 0.70A 4ygfB-3ml5A:
25.8		 4ygfB-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.42A 4ygfB-3ml5A:
25.8		 4ygfB-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.22A 4ygfC-3ml5A:
19.5		 4ygfC-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.29A 4ygfD-3ml5A:
4.1		 4ygfD-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.01A 4ygfD-3ml5A:
4.1		 4ygfD-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.38A 4ygfD-3ml5A:
4.1		 4ygfD-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 12 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.31A 4ygfE-3ml5A:
26.1		 4ygfE-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 0.69A 4ygfE-3ml5A:
26.1		 4ygfE-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.41A 4ygfE-3ml5A:
26.1		 4ygfE-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.23A 4ygfF-3ml5A:
26.0		 4ygfF-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.27A 4ygfG-3ml5A:
6.1		 4ygfG-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.04A 4ygfG-3ml5A:
6.1		 4ygfG-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.23A 4ygfH-3ml5A:
25.7		 4ygfH-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.36A 4ygfH-3ml5A:
25.7		 4ygfH-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.37A 4yhaA-3ml5A:
26.2		 4yhaA-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 0.47A 4yhaB-3ml5A:
25.3		 4yhaB-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.10A 4yhaB-3ml5A:
25.3		 4yhaB-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.30A 4yhaC-3ml5A:
26.3		 4yhaC-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.49A 4yhaC-3ml5A:
26.3		 4yhaC-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.40A 4yhaD-3ml5A:
25.1		 4yhaD-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A 119
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 1.45A 4yhaD-3ml5A:
25.1		 4yhaD-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
None
 0.31A 4yhaE-3ml5A:
26.3		 4yhaE-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 143
LEU A 198
THR A 199
PRO A 202
 ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.99A 4yhaE-3ml5A:
26.3		 4yhaE-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.57A 4yhaF-3ml5A:
23.5		 4yhaF-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.28A 4yhaG-3ml5A:
25.8		 4yhaG-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 10 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.40A 4yhaH-3ml5A:
25.5		 4yhaH-3ml5A:
28.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.95A 5c8iA-3ml5A:
43.0		 5c8iA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.15A 5c8iA-3ml5A:
43.0		 5c8iA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
GLU A 117
VAL A 121
PHE A 131
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
None
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
 1.25A 5c8iA-3ml5A:
43.0		 5c8iA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.30A 5c8iA-3ml5A:
43.0		 5c8iA-3ml5A:
55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.42A 5c8iA-3ml5A:
43.0		 5c8iA-3ml5A:
55.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 LEU A  47
TYR A 191
ARG A 189
ILE A 210
VAL A 143
 None
None
None
None
AZM  A 264 ( 4.9A)
 1.33A 5hjiA-3ml5A:
undetectable		 5hjiA-3ml5A:
21.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.11A 5jn8A-3ml5A:
32.8		 5jn8A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.28A 5jn8A-3ml5A:
32.8		 5jn8A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.37A 5jn8A-3ml5A:
32.8		 5jn8A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.95A 5jn8A-3ml5A:
32.8		 5jn8A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.44A 5jn8A-3ml5A:
32.8		 5jn8A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.02A 5jn8B-3ml5A:
33.0		 5jn8B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.11A 5jn8B-3ml5A:
33.0		 5jn8B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 AZM  A 264 (-4.1A)
None
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
None
 1.46A 5jn8B-3ml5A:
33.0		 5jn8B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.29A 5jn8B-3ml5A:
33.0		 5jn8B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.98A 5jn8B-3ml5A:
33.0		 5jn8B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.27A 5jn8C-3ml5A:
32.6		 5jn8C-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
GLU A 106
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.90A 5jn8D-3ml5A:
32.3		 5jn8D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.24A 5jn8D-3ml5A:
32.3		 5jn8D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.00A 5jn8D-3ml5A:
32.3		 5jn8D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.43A 5jn8D-3ml5A:
32.3		 5jn8D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.12A 5jn9A-3ml5A:
32.8		 5jn9A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.26A 5jn9A-3ml5A:
32.8		 5jn9A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
THR A 200
THR A 199
TRP A   5
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.5A)
AZM  A 264 (-3.4A)
None
 1.42A 5jn9A-3ml5A:
32.8		 5jn9A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.38A 5jn9A-3ml5A:
32.8		 5jn9A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.92A 5jn9A-3ml5A:
32.8		 5jn9A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.48A 5jn9A-3ml5A:
32.8		 5jn9A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.07A 5jn9B-3ml5A:
33.1		 5jn9B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.10A 5jn9B-3ml5A:
33.1		 5jn9B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.30A 5jn9B-3ml5A:
33.1		 5jn9B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.42A 5jn9B-3ml5A:
33.1		 5jn9B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.42A 5jn9B-3ml5A:
33.1		 5jn9B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.21A 5jn9C-3ml5A:
32.7		 5jn9C-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A  94
THR A 200
THR A 199
TRP A   5
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.5A)
AZM  A 264 (-3.4A)
None
 1.39A 5jn9C-3ml5A:
32.7		 5jn9C-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.99A 5jn9C-3ml5A:
32.7		 5jn9C-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.45A 5jn9C-3ml5A:
32.7		 5jn9C-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.12A 5jn9D-3ml5A:
32.3		 5jn9D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.25A 5jn9D-3ml5A:
32.3		 5jn9D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
THR A 200
THR A 199
TRP A   5
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.5A)
AZM  A 264 (-3.4A)
None
 1.37A 5jn9D-3ml5A:
32.3		 5jn9D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.35A 5jn9D-3ml5A:
32.3		 5jn9D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.91A 5jn9D-3ml5A:
32.3		 5jn9D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 ASN A  62
SER A  65
GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
 None
None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.43A 5jnaA-3ml5A:
32.7		 5jnaA-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.98A 5jnaA-3ml5A:
32.7		 5jnaA-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.10A 5jnaA-3ml5A:
32.7		 5jnaA-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.01A 5jnaA-3ml5A:
32.7		 5jnaA-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 ASN A  62
SER A  65
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.43A 5jnaB-3ml5A:
33.0		 5jnaB-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.02A 5jnaB-3ml5A:
33.0		 5jnaB-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.11A 5jnaB-3ml5A:
33.0		 5jnaB-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.34A 5jnaB-3ml5A:
33.0		 5jnaB-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.47A 5jnaB-3ml5A:
33.0		 5jnaB-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 ASN A  62
SER A  65
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
 None
None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.45A 5jnaC-3ml5A:
32.5		 5jnaC-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.04A 5jnaC-3ml5A:
32.5		 5jnaC-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.08A 5jnaC-3ml5A:
32.5		 5jnaC-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.97A 5jnaC-3ml5A:
32.5		 5jnaC-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 SER A  65
HIS A  96
VAL A 143
LEU A 198
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.12A 5jnaC-3ml5A:
32.5		 5jnaC-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 ASN A  62
SER A  65
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.40A 5jnaD-3ml5A:
32.2		 5jnaD-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.03A 5jnaD-3ml5A:
32.2		 5jnaD-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.06A 5jnaD-3ml5A:
32.2		 5jnaD-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.94A 5jnaD-3ml5A:
32.2		 5jnaD-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.5A)
 1.10A 5jncA-3ml5A:
32.7		 5jncA-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
GLU A 117
VAL A 121
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
None
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
 1.28A 5jncA-3ml5A:
32.7		 5jncA-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.30A 5jncA-3ml5A:
32.7		 5jncA-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 4.6A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.99A 5jncA-3ml5A:
32.7		 5jncA-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.29A 5jncB-3ml5A:
33.1		 5jncB-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.36A 5jncB-3ml5A:
33.1		 5jncB-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.41A 5jncB-3ml5A:
33.1		 5jncB-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.23A 5jncC-3ml5A:
32.6		 5jncC-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A  94
THR A 200
THR A 199
TRP A   5
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.5A)
AZM  A 264 (-3.4A)
None
 1.43A 5jncC-3ml5A:
32.6		 5jncC-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.45A 5jncC-3ml5A:
32.6		 5jncC-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.24A 5jncD-3ml5A:
32.3		 5jncD-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.47A 5jncD-3ml5A:
32.3		 5jncD-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.27A 5ku6A-3ml5A:
32.7		 5ku6A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
THR A 200
THR A 199
TRP A   5
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.5A)
AZM  A 264 (-3.4A)
None
 1.41A 5ku6A-3ml5A:
32.7		 5ku6A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.37A 5ku6A-3ml5A:
32.7		 5ku6A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.95A 5ku6A-3ml5A:
32.7		 5ku6A-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.09A 5ku6B-3ml5A:
33.0		 5ku6B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.15A 5ku6B-3ml5A:
33.0		 5ku6B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.27A 5ku6B-3ml5A:
33.0		 5ku6B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.36A 5ku6B-3ml5A:
33.0		 5ku6B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.44A 5ku6B-3ml5A:
33.0		 5ku6B-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.24A 5ku6C-3ml5A:
32.7		 5ku6C-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.10A 5ku6D-3ml5A:
32.3		 5ku6D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.24A 5ku6D-3ml5A:
32.3		 5ku6D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A  94
THR A 200
THR A 199
TRP A   5
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.5A)
AZM  A 264 (-3.4A)
None
 1.38A 5ku6D-3ml5A:
32.3		 5ku6D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.43A 5ku6D-3ml5A:
32.3		 5ku6D-3ml5A:
34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 7 GLN A  92
HIS A  94
VAL A 121
PHE A 131
LEU A 198
THR A 199
THR A 200
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.25A 5m78A-3ml5A:
42.9		 5m78A-3ml5A:
56.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 7 VAL A 143
LEU A 198
THR A 199
THR A 200
 AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 0.89A 5m78A-3ml5A:
42.9		 5m78A-3ml5A:
56.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 7 HIS A  96
HIS A 119
LEU A 118
VAL A 121
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
None
AZM  A 264 (-4.7A)
 1.04A 5m8rA-3ml5A:
undetectable		 5m8rA-3ml5A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 8 HIS A  96
HIS A 119
LEU A 118
VAL A 121
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
None
AZM  A 264 (-4.7A)
 1.01A 5m8rC-3ml5A:
undetectable		 5m8rC-3ml5A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 8 HIS A  96
HIS A 119
LEU A 118
VAL A 121
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
None
AZM  A 264 (-4.7A)
 0.98A 5m8rD-3ml5A:
undetectable		 5m8rD-3ml5A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		3 / 3 THR A 200
HIS A  96
ASN A 244
 AZM  A 264 (-3.5A)
ZN  A 263 ( 3.2A)
None
 1.01A 5n4tA-3ml5A:
undetectable		 5n4tA-3ml5A:
26.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 6 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.16A 5ogjA-3ml5A:
42.3		 5ogjA-3ml5A:
53.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 6 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.26A 5ogjA-3ml5A:
42.3		 5ogjA-3ml5A:
53.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 6 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.15A 5ogjB-3ml5A:
42.1		 5ogjB-3ml5A:
53.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 6 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.26A 5ogjB-3ml5A:
42.1		 5ogjB-3ml5A:
53.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 5 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.16A 5ohhA-3ml5A:
42.2		 5ohhA-3ml5A:
53.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 5 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 0.28A 5ohhA-3ml5A:
42.2		 5ohhA-3ml5A:
53.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		4 / 6 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.16A 5ohhB-3ml5A:
42.2		 5ohhB-3ml5A:
53.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 6 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.24A 5ohhB-3ml5A:
42.2		 5ohhB-3ml5A:
53.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 12 ILE A  22
PHE A 131
ALA A 142
LEU A 141
ALA A 134
 None
AZM  A 264 (-4.4A)
None
None
None
 1.03A 5oy02-3ml5A:
undetectable		 5oy02-3ml5A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
None
 0.32A 5tt3A-3ml5A:
26.2		 5tt3A-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 10 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
PRO A 202
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 1.11A 5tt3A-3ml5A:
26.2		 5tt3A-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  94
HIS A 119
THR A 199
PRO A 201
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-3.4A)
None
None
 1.33A 5tt3A-3ml5A:
26.2		 5tt3A-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.31A 5tt3B-3ml5A:
24.4		 5tt3B-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		9 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
None
 0.32A 5tt3C-3ml5A:
26.3		 5tt3C-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
LEU A 198
THR A 199
PRO A 202
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.95A 5tt3C-3ml5A:
26.3		 5tt3C-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.33A 5tt3E-3ml5A:
26.1		 5tt3E-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.05A 5tt3E-3ml5A:
26.1		 5tt3E-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.38A 5tt3F-3ml5A:
25.5		 5tt3F-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 8 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.48A 5tt3F-3ml5A:
25.5		 5tt3F-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.28A 5tt3G-3ml5A:
25.5		 5tt3G-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.05A 5tt3G-3ml5A:
25.5		 5tt3G-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.1A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
None
 0.43A 5tt3H-3ml5A:
25.2		 5tt3H-3ml5A:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		3 / 3 GLU A 106
TRP A 209
HIS A  94
 ZN  A 263 ( 4.6A)
None
ZN  A 263 ( 3.2A)
 1.09A 5xipA-3ml5A:
undetectable		 5xipA-3ml5A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 ASN A  62
HIS A  64
GLN A  92
HIS A  94
HIS A  96
PHE A 131
THR A 200
 None
None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.5A)
 0.78A 6bbsA-3ml5A:
33.1		 6bbsA-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
 1.13A 6bbsA-3ml5A:
33.1		 6bbsA-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		10 / 12 TRP A   5
ASN A  62
HIS A  64
GLN A  92
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 0.59A 6bbsA-3ml5A:
33.1		 6bbsA-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 TRP A   5
HIS A  64
HIS A  94
THR A 199
THR A 200
TRP A 209
 None
None
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.36A 6bbsA-3ml5A:
33.1		 6bbsA-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.38A 6bc9A-3ml5A:
43.0		 6bc9A-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		12 / 12 TRP A   5
ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 None
None
AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.48A 6bc9A-3ml5A:
43.0		 6bc9A-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		8 / 12 TRP A   5
GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.10A 6bc9A-3ml5A:
43.0		 6bc9A-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 TRP A   5
HIS A  94
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 1.32A 6bc9A-3ml5A:
43.0		 6bc9A-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 TRP A   5
HIS A  96
VAL A 143
LEU A 198
THR A 200
PRO A 202
 None
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.02A 6bc9A-3ml5A:
43.0		 6bc9A-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 TRP A  16
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
TRP A 209
 None
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.46A 6bc9A-3ml5A:
43.0		 6bc9A-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		5 / 5 HIS A  64
GLU A 106
HIS A 119
LEU A 141
VAL A 143
 None
ZN  A 263 ( 4.6A)
ZN  A 263 ( 3.1A)
None
AZM  A 264 ( 4.9A)
 0.33A 6bc9A-3ml5A:
43.0		 6bc9A-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
PRO A 202
 None
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.16A 6bccA-3ml5A:
43.0		 6bccA-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
LEU A 198
THR A 199
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
 1.43A 6bccA-3ml5A:
43.0		 6bccA-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
PHE A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 AZM  A 264 (-4.1A)
ZN  A 263 ( 3.2A)
ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-4.4A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 0.29A 6bccA-3ml5A:
43.0		 6bccA-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  94
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 263 ( 3.2A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
None
 1.38A 6bccA-3ml5A:
43.0		 6bccA-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 ZN  A 263 ( 3.2A)
AZM  A 264 (-4.7A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.01A 6bccA-3ml5A:
43.0		 6bccA-3ml5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3ml5 CARBONIC ANHYDRASE 7
(Homo
sapiens) 		6 / 12 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
PRO A 202
 ZN  A 263 ( 3.1A)
ZN  A 263 ( 3.2A)
AZM  A 264 ( 4.9A)
AZM  A 264 (-3.4A)
AZM  A 264 (-3.5A)
None
 1.40A 6bccA-3ml5A:
43.0		 6bccA-3ml5A:
18.53