SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mlg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 3mlg 2X CHIMERA OF
HELICOBACTER PYLORI
PROTEIN HP0242
(Helicobacter
pylori) 		4 / 4 LEU A  34
SER A  85
LEU A 126
LEU A 123
 None
 1.16A 1yajA-3mlgA:
undetectable		 1yajA-3mlgA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 3mlg 2X CHIMERA OF
HELICOBACTER PYLORI
PROTEIN HP0242
(Helicobacter
pylori) 		4 / 4 LEU A 123
SER A 174
LEU A  37
LEU A  34
 None
 1.16A 1yajA-3mlgA:
undetectable		 1yajA-3mlgA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 3mlg 2X CHIMERA OF
HELICOBACTER PYLORI
PROTEIN HP0242
(Helicobacter
pylori) 		4 / 6 LEU A  43
LEU A 130
LEU A 133
PHE A 146
 None
 0.93A 5gs4A-3mlgA:
undetectable		 5gs4A-3mlgA:
21.54