SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mln'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 8 VAL A 128
LEU A 130
MET A 232
VAL A 234
 None
 0.97A 1fduB-3mlnA:
undetectable		 1fduB-3mlnA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 7 SER A 178
ASP A 179
GLU A  94
GLU A 149
 None
 1.20A 1knyA-3mlnA:
undetectable
1knyB-3mlnA:
undetectable		 1knyA-3mlnA:
20.22
1knyB-3mlnA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 7 ARG A 129
SER A 216
VAL A 214
VAL A 225
 None
 0.72A 3o14A-3mlnA:
undetectable		 3o14A-3mlnA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 6 PHE A 211
LEU A  62
PRO A  59
ARG A 209
 None
 1.45A 4yv5B-3mlnA:
undetectable		 4yv5B-3mlnA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 6 PHE A 211
LEU A  62
PRO A  59
ARG A 209
 None
 1.46A 4yv5A-3mlnA:
undetectable		 4yv5A-3mlnA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 5 GLU A 123
THR A 122
GLU A  85
LEU A 188
 None
 1.17A 5hm8A-3mlnA:
undetectable		 5hm8A-3mlnA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 5 GLU A 123
THR A 122
GLU A  85
LEU A 188
 None
 1.18A 5hm8B-3mlnA:
undetectable		 5hm8B-3mlnA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 5 GLU A 123
THR A 122
GLU A  85
LEU A 188
 None
 1.17A 5hm8C-3mlnA:
undetectable		 5hm8C-3mlnA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 5 GLU A 123
THR A 122
GLU A  85
LEU A 188
 None
 1.17A 5hm8D-3mlnA:
undetectable		 5hm8D-3mlnA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 5 GLU A 123
THR A 122
GLU A  85
LEU A 188
 None
 1.17A 5hm8E-3mlnA:
undetectable		 5hm8E-3mlnA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 5 GLU A 123
THR A 122
GLU A  85
LEU A 188
 None
 1.17A 5hm8F-3mlnA:
undetectable		 5hm8F-3mlnA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 5 GLU A 123
THR A 122
GLU A  85
LEU A 188
 None
 1.28A 5hm8G-3mlnA:
undetectable		 5hm8G-3mlnA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mln TRANSCRIPTION FACTOR
COE1
(Mus
musculus) 		4 / 5 GLU A 123
THR A 122
GLU A  85
LEU A 188
 None
 1.18A 5hm8H-3mlnA:
undetectable		 5hm8H-3mlnA:
17.19