SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7A_B_PFLB4002_1 (SERUM ALBUMIN)	3mmh	METHIONINE-R-SULFOXI DE REDUCTASE (Neisseria meningitidis)	4 / 6	LEU A 64 VAL A 130 VAL A 84 GLN A 87	None None SME A 168 (-3.8A) None	1.14A	1e7aB-3mmhA: undetectable	1e7aB-3mmhA: 15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZUC_A_T98A201_1 (PROGESTERONE RECEPTOR)	3mmh	METHIONINE-R-SULFOXI DE REDUCTASE (Neisseria meningitidis)	5 / 10	LEU A 43 LEU A 147 LEU A 19 THR A 39 PHE A 54	None	1.46A	1zucA-3mmhA: undetectable	1zucA-3mmhA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PKK_A_2FAA501_2 (ADENOSINE KINASE)	3mmh	METHIONINE-R-SULFOXI DE REDUCTASE (Neisseria meningitidis)	4 / 4	ALA A 153 VAL A 130 PHE A 122 THR A 94	None None None MRD A 177 (-4.5A)	1.40A	2pkkA-3mmhA: undetectable	2pkkA-3mmhA: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_A_STRA604_1 (CYTOCHROME P450 21-HYDROXYLASE)	3mmh	METHIONINE-R-SULFOXI DE REDUCTASE (Neisseria meningitidis)	6 / 12	VAL A 26 VAL A 42 LEU A 43 GLY A 53 VAL A 119 LEU A 121	MG A 174 ( 4.6A) MG A 170 (-4.0A) None None None None	1.49A	4y8wA-3mmhA: undetectable	4y8wA-3mmhA: 18.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7A_B_PFLB4002_1","SERUM ALBUMIN","3mmh","METHIONINE-R-SULFOXIDE REDUCTASE","Neisseria meningitidis",4,"LEU A  64;VAL A 130;VAL A  84;GLN A  87","None;None;SME A 168 (-3.8A);None","1.14A","1e7aB-3mmhA:undetectable","1e7aB-3mmhA:15.17"],["1ZUC_A_T98A201_1","PROGESTERONE RECEPTOR","3mmh","METHIONINE-R-SULFOXIDE REDUCTASE","Neisseria meningitidis",5,"LEU A  43;LEU A 147;LEU A  19;THR A  39;PHE A  54","None","1.46A","1zucA-3mmhA:undetectable","1zucA-3mmhA:20.16"],["2PKK_A_2FAA501_2","ADENOSINE KINASE","3mmh","METHIONINE-R-SULFOXIDE REDUCTASE","Neisseria meningitidis",4,"ALA A 153;VAL A 130;PHE A 122;THR A  94","None;None;None;MRD A 177 (-4.5A)","1.40A","2pkkA-3mmhA:undetectable","2pkkA-3mmhA:22.86"],["4Y8W_A_STRA604_1","CYTOCHROME P450 21-HYDROXYLASE","3mmh","METHIONINE-R-SULFOXIDE REDUCTASE","Neisseria meningitidis",6,"VAL A  26;VAL A  42;LEU A  43;GLY A  53;VAL A 119;LEU A 121"," MG A 174 ( 4.6A); MG A 170 (-4.0A);None;None;None;None","1.49A","4y8wA-3mmhA:undetectable","4y8wA-3mmhA:18.18"]]