SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mmp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 ASP A  97
VAL A  75
ILE A 131
ILE A 104
PHE A 114
 None
 1.17A 1c9hA-3mmpA:
undetectable		 1c9hA-3mmpA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		5 / 12 ILE G 135
PHE G 296
SER G 283
ILE G 320
LEU G 331
 None
 1.18A 1dlsA-3mmpG:
undetectable		 1dlsA-3mmpG:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
coli;
Escherichia
virus
Qbeta) 		4 / 8 LEU G 506
PHE A1218
LEU G 513
LEU G 510
 None
 1.04A 1e7cA-3mmpG:
1.6		 1e7cA-3mmpG:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 8 ASP A1369
ILE A1298
PRO A1213
LEU A1211
 None
 0.89A 1hmyA-3mmpA:
undetectable		 1hmyA-3mmpA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		3 / 3 ARG G 431
THR G 462
VAL G 473
 None
 1.01A 1hxbA-3mmpG:
undetectable		 1hxbA-3mmpG:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
coli;
Escherichia
virus
Qbeta) 		5 / 12 GLY A1386
LEU G 544
ILE G 541
ILE A1310
LEU A1311
 None
 1.24A 1kyvA-3mmpA:
undetectable
1kyvE-3mmpA:
3.6		 1kyvA-3mmpA:
13.42
1kyvE-3mmpA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
coli;
Escherichia
virus
Qbeta) 		5 / 12 ILE A1310
LEU A1311
GLY A1386
LEU G 544
ILE G 541
 None
 1.25A 1kyvB-3mmpA:
4.5
1kyvC-3mmpA:
4.5		 1kyvB-3mmpA:
13.42
1kyvC-3mmpA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
coli;
Escherichia
virus
Qbeta) 		5 / 12 ILE A1310
LEU A1311
GLY A1386
LEU G 544
ILE G 541
 None
 1.23A 1kyvC-3mmpA:
4.5
1kyvD-3mmpA:
4.6		 1kyvC-3mmpA:
13.42
1kyvD-3mmpA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
coli;
Escherichia
virus
Qbeta) 		5 / 12 ILE A1310
LEU A1311
GLY A1386
LEU G 544
ILE G 541
 None
 1.24A 1kyvD-3mmpA:
4.6
1kyvE-3mmpA:
3.6		 1kyvD-3mmpA:
13.42
1kyvE-3mmpA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		3 / 3 PHE G  96
TRP G  93
GLU G  89
 None
 1.01A 1mogA-3mmpG:
undetectable		 1mogA-3mmpG:
7.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 7 VAL A1308
GLY A1386
ILE A1341
VAL A1360
 None
 0.79A 1p2yA-3mmpA:
undetectable		 1p2yA-3mmpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 8 GLY A1386
VAL A1308
GLU A1307
ILE A1376
 None
 0.75A 1pk7B-3mmpA:
3.5		 1pk7B-3mmpA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 7 TYR G 357
ASP G 359
ASP G 360
HIS G 400
 None
 1.43A 1t03A-3mmpG:
2.1		 1t03A-3mmpG:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 10 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.94A 1t3rA-3mmpA:
undetectable		 1t3rA-3mmpA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 10 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.95A 1t7iA-3mmpA:
undetectable		 1t7iA-3mmpA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 4 LEU G 291
SER G 338
LEU G 240
LEU G 331
 None
 1.18A 1yajA-3mmpG:
undetectable		 1yajA-3mmpG:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 5 LEU G 291
SER G 338
LEU G 240
LEU G 331
 None
 1.16A 1yajD-3mmpG:
undetectable		 1yajD-3mmpG:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		5 / 11 ILE G 139
ILE G 135
TYR G 327
GLY G 235
LEU G 299
 None
 1.04A 2azyA-3mmpG:
undetectable		 2azyA-3mmpG:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 5 LEU G 363
PHE G 375
VAL G 343
ALA G 367
 None
 1.11A 2cizA-3mmpG:
undetectable		 2cizA-3mmpG:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.97A 2f81B-3mmpA:
undetectable		 2f81B-3mmpA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 5 LEU G 454
PRO G 455
LEU G 458
ILE G 423
 None
 0.88A 2qd4A-3mmpG:
undetectable		 2qd4A-3mmpG:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 11 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.89A 2r5qB-3mmpA:
undetectable		 2r5qB-3mmpA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 10 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.89A 2r5qD-3mmpA:
undetectable		 2r5qD-3mmpA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 8 TYR G 411
ALA G  30
ALA G  34
LEU G  71
 None
 0.75A 2wx2B-3mmpG:
undetectable		 2wx2B-3mmpG:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		5 / 12 GLY G 227
LEU G 234
LEU G 175
SER G 155
GLY G 157
 None
 0.89A 3g2oA-3mmpG:
undetectable		 3g2oA-3mmpG:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.88A 3jvyB-3mmpA:
undetectable		 3jvyB-3mmpA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 8 GLY A1384
ILE A1341
PHE A1374
PHE A1332
 None
 0.94A 3ko0B-3mmpA:
undetectable
3ko0J-3mmpA:
undetectable		 3ko0B-3mmpA:
9.19
3ko0J-3mmpA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 GLY A1015
VAL A1104
ALA A1077
LEU A1195
ILE A1199
 None
 1.03A 3ku1H-3mmpA:
undetectable		 3ku1H-3mmpA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 8 TYR G 411
ALA G  30
ALA G  34
LEU G  71
 None
 0.98A 3l4dA-3mmpG:
undetectable		 3l4dA-3mmpG:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.95A 3n3iA-3mmpA:
undetectable		 3n3iA-3mmpA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		3 / 3 VAL A 226
VAL A 190
SER A 186
 None
 0.67A 3n8xB-3mmpA:
undetectable		 3n8xB-3mmpA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_A_URFA521_1
(RNA DEPENDENT RNA
POLYMERASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 5 ARG G 220
ASP G 274
ASP G 359
ASP G 360
 None
 1.38A 3naiA-3mmpG:
13.9		 3naiA-3mmpG:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_B_URFB521_1
(RNA DEPENDENT RNA
POLYMERASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 4 ARG G 220
ASP G 274
ASP G 359
ASP G 360
 None
 1.38A 3naiB-3mmpG:
3.0		 3naiB-3mmpG:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 5 ARG G 220
ASP G 274
ASP G 359
ASP G 360
 None
 1.36A 3naiC-3mmpG:
6.2		 3naiC-3mmpG:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 7 ALA A 250
VAL A 155
VAL A 252
LEU A 245
 None
 0.86A 3o14A-3mmpA:
undetectable		 3o14A-3mmpA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 11 LEU A1103
ASP A1161
GLY A1126
VAL A1125
ILE A1130
 None
 0.96A 3oxxD-3mmpA:
undetectable		 3oxxD-3mmpA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 10 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.94A 3oy4B-3mmpA:
undetectable		 3oy4B-3mmpA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA214_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 10 PHE A1322
VAL A1308
PHE A1374
PHE A1304
GLY A1339
 None
 1.49A 3r6wA-3mmpA:
7.0
3r6wB-3mmpA:
5.4		 3r6wA-3mmpA:
13.99
3r6wB-3mmpA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 9 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.93A 3s53A-3mmpA:
undetectable		 3s53A-3mmpA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.98A 3s56A-3mmpA:
undetectable		 3s56A-3mmpA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.96A 3tkgC-3mmpA:
undetectable		 3tkgC-3mmpA:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		3 / 3 LYS A1208
PRO A1209
LEU A1211
 None
 0.86A 3tpxE-3mmpA:
undetectable		 3tpxE-3mmpA:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 9 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.93A 3u7sA-3mmpA:
undetectable		 3u7sA-3mmpA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		3 / 3 LEU G 454
PRO G 455
LEU G 458
 None
 0.46A 3w1wB-3mmpG:
undetectable		 3w1wB-3mmpG:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 10 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.98A 4dqbB-3mmpA:
undetectable		 4dqbB-3mmpA:
9.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 9 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 1.01A 4dqcB-3mmpA:
undetectable		 4dqcB-3mmpA:
9.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 10 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.97A 4dqeB-3mmpA:
undetectable		 4dqeB-3mmpA:
9.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 10 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.96A 4dqhB-3mmpA:
undetectable		 4dqhB-3mmpA:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		4 / 4 LEU G 454
PRO G 455
LEU G 458
ILE G 423
 None
 0.93A 4f4dB-3mmpG:
undetectable		 4f4dB-3mmpG:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 ARG A1381
GLU A1378
GLY A1380
VAL A1350
TYR A1326
 None
 1.32A 4ffwA-3mmpA:
4.1		 4ffwA-3mmpA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		5 / 12 GLY G 237
GLY G 326
LEU G 302
GLN G 233
ILE G 239
 None
 1.10A 4fr0A-3mmpG:
undetectable		 4fr0A-3mmpG:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 5 ALA A  29
ILE A  37
LEU A  11
ASN A  39
 None
 1.03A 4g19A-3mmpA:
undetectable		 4g19A-3mmpA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		5 / 12 ILE G 494
PHE G 410
LEU G  37
LEU G 472
TRP G 439
 None
 1.39A 4j03A-3mmpG:
undetectable		 4j03A-3mmpG:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8W_G_MTXG301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 9 PHE A1374
GLY A1317
GLY A1384
LEU A1311
GLU A1315
 None
 1.31A 4l8wG-3mmpA:
4.2		 4l8wG-3mmpA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8W_I_MTXI301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 9 PHE A1374
GLY A1317
GLY A1384
LEU A1311
GLU A1315
 None
 1.21A 4l8wI-3mmpA:
3.1		 4l8wI-3mmpA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 PHE A1322
LEU A1311
GLY A1339
THR A1382
MET A1358
 None
 1.24A 4mubA-3mmpA:
undetectable		 4mubA-3mmpA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 10 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.94A 4njtB-3mmpA:
undetectable		 4njtB-3mmpA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 9 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.94A 4q1wA-3mmpA:
undetectable		 4q1wA-3mmpA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 10 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.95A 4q1yA-3mmpA:
undetectable		 4q1yA-3mmpA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 6 GLU A 178
PHE A 179
GLU A 193
VAL A 190
 None
 1.18A 5h4dA-3mmpA:
undetectable		 5h4dA-3mmpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 11 ASP A  97
VAL A  75
ILE A 131
ILE A  71
PHE A 114
 None
 1.26A 5hw8G-3mmpA:
undetectable		 5hw8G-3mmpA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 6 THR A 253
GLY A 254
PHE A 255
ILE A  72
 None
 0.88A 5kmfA-3mmpA:
undetectable
5kmfC-3mmpA:
2.4		 5kmfA-3mmpA:
18.24
5kmfC-3mmpA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 7 GLY A1316
ASP A1314
GLY A1353
ILE A1310
 None
 0.66A 5kqyB-3mmpA:
undetectable		 5kqyB-3mmpA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 9 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 1.01A 5kr0B-3mmpA:
undetectable		 5kr0B-3mmpA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 8 GLY A1316
ASP A1314
GLY A1353
ILE A1310
 None
 0.65A 5kr1B-3mmpA:
undetectable		 5kr1B-3mmpA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		3 / 3 LEU G 426
LEU G 429
TRP G 432
 None
 0.86A 5nwuA-3mmpG:
undetectable		 5nwuA-3mmpG:
4.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		5 / 12 ALA G 337
LEU G 138
ILE G 139
TYR G 327
CYH G 287
 None
 1.25A 5vlmA-3mmpG:
undetectable		 5vlmA-3mmpG:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
coli;
Escherichia
virus
Qbeta) 		5 / 12 VAL A 234
GLY A1317
VAL A1383
PRO A1328
GLY G 486
 None
 1.08A 6brdC-3mmpA:
undetectable		 6brdC-3mmpA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 GLY A  16
ALA A  17
ASP A  21
GLY A 126
ILE A 125
 None
 0.89A 6dj1A-3mmpA:
undetectable		 6dj1A-3mmpA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 9 LEU A1134
PRO A1111
VAL A1132
SER A1158
LEU A1156
 None
 1.31A 6fdyU-3mmpA:
undetectable		 6fdyU-3mmpA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		4 / 6 GLU A 262
ARG A 133
PHE A 258
VAL A 153
 None
 0.88A 6fgdA-3mmpA:
undetectable		 6fgdA-3mmpA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		3 / 3 ARG A1230
GLY A1271
GLU A1272
 None
 0.50A 6fgdA-3mmpA:
undetectable		 6fgdA-3mmpA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		3 / 3 ARG G  67
LYS G 399
TYR G 401
 None
 1.31A 6gnaA-3mmpG:
undetectable		 6gnaA-3mmpG:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		3 / 3 ARG G  67
LYS G 399
TYR G 401
 None
 1.31A 6gnbA-3mmpG:
undetectable		 6gnbA-3mmpG:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
(Escherichia
virus
Qbeta) 		3 / 3 ASP G 274
ASP G 280
ASN G 207
 None
 0.87A 6gngB-3mmpG:
undetectable		 6gngB-3mmpG:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3mmp ELONGATION FACTOR TU
2, ELONGATION FACTOR
TS
(Escherichia
coli) 		5 / 12 VAL A1337
ILE A1310
TYR A1326
THR A1340
PHE A1304
 None
 1.34A 6j20A-3mmpA:
undetectable		 6j20A-3mmpA:
19.10