SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mmt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 5 LYS A 223
GLU A 178
ALA A 261
LEU A  12
 2FP  A 350 (-2.2A)
2FP  A 350 (-2.6A)
None
None
 1.10A 1eta1-3mmtA:
undetectable		 1eta1-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 5 LYS A 223
GLU A 178
ALA A 261
LEU A  12
 2FP  A 350 (-2.2A)
2FP  A 350 (-2.6A)
None
None
 1.11A 1eta2-3mmtA:
undetectable		 1eta2-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 6 LYS A 223
GLU A 178
ALA A 261
LEU A  12
 2FP  A 350 (-2.2A)
2FP  A 350 (-2.6A)
None
None
 1.10A 1etb1-3mmtA:
undetectable		 1etb1-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 4 THR A 199
LEU A 203
VAL A 206
LEU A 210
 None
 0.57A 1fbmB-3mmtA:
undetectable		 1fbmB-3mmtA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 4 THR A 199
LEU A 203
VAL A 206
LEU A 210
 None
 0.64A 1fbmD-3mmtA:
undetectable		 1fbmD-3mmtA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 5 THR A 199
LEU A 203
VAL A 206
LEU A 210
 None
 0.59A 1fbmE-3mmtA:
undetectable		 1fbmE-3mmtA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		5 / 11 LYS A 223
GLU A 178
ALA A 261
LEU A  12
THR A 290
 2FP  A 350 (-2.2A)
2FP  A 350 (-2.6A)
None
None
None
 1.04A 1ictA-3mmtA:
undetectable
1ictC-3mmtA:
undetectable		 1ictA-3mmtA:
15.70
1ictC-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 6 LYS A 223
ALA A 261
LEU A  12
THR A 290
 2FP  A 350 (-2.2A)
None
None
None
 1.00A 1ictB-3mmtA:
undetectable		 1ictB-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 7 PHE A  53
ALA A  22
ILE A  29
GLU A  24
 None
None
None
2FP  A 350 ( 4.9A)
 0.93A 1oniA-3mmtA:
undetectable
1oniB-3mmtA:
undetectable		 1oniA-3mmtA:
19.88
1oniB-3mmtA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 7 PHE A  53
ALA A  22
ILE A  29
GLU A  24
 None
None
None
2FP  A 350 ( 4.9A)
 0.89A 1oniD-3mmtA:
1.4
1oniF-3mmtA:
undetectable		 1oniD-3mmtA:
19.88
1oniF-3mmtA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 7 ILE A  29
GLU A  24
PHE A  53
ALA A  22
 None
2FP  A 350 ( 4.9A)
None
None
 1.00A 1oniD-3mmtA:
undetectable
1oniE-3mmtA:
undetectable		 1oniD-3mmtA:
19.88
1oniE-3mmtA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 7 ILE A  29
GLU A  24
PHE A  53
ALA A  22
 None
2FP  A 350 ( 4.9A)
None
None
 0.98A 1oniG-3mmtA:
undetectable
1oniI-3mmtA:
undetectable		 1oniG-3mmtA:
19.88
1oniI-3mmtA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 6 LEU A  52
TRP A 305
LEU A 302
PHE A  33
 None
 1.41A 1rukH-3mmtA:
undetectable
1rukL-3mmtA:
undetectable		 1rukH-3mmtA:
22.00
1rukL-3mmtA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		5 / 10 LEU A 203
VAL A 257
VAL A 177
PRO A 286
LEU A 249
 None
 1.31A 1sv5A-3mmtA:
0.6		 1sv5A-3mmtA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 8 VAL A  98
TYR A 164
TYR A 127
LEU A 124
 None
 0.99A 1z2bB-3mmtA:
undetectable		 1z2bB-3mmtA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 5 LEU A   5
GLY A  95
ALA A   9
ILE A   8
 None
 0.80A 2aohB-3mmtA:
undetectable		 2aohB-3mmtA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		5 / 6 LYS A 223
GLU A 178
ALA A 261
LEU A  12
THR A 290
 2FP  A 350 (-2.2A)
2FP  A 350 (-2.6A)
None
None
None
 1.19A 2roxB-3mmtA:
undetectable		 2roxB-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		3 / 3 PHE A 134
SER A 292
LEU A  20
 None
2FP  A 350 ( 4.7A)
None
 0.72A 2w1bA-3mmtA:
undetectable		 2w1bA-3mmtA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 7 LYS A 223
ALA A 261
LEU A  12
THR A 290
 2FP  A 350 (-2.2A)
None
None
None
 0.94A 3cfqA-3mmtA:
undetectable
3cfqB-3mmtA:
undetectable		 3cfqA-3mmtA:
15.70
3cfqB-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 6 LYS A 223
ALA A 261
LEU A  12
THR A 290
 2FP  A 350 (-2.2A)
None
None
None
 0.91A 3d2tB-3mmtA:
undetectable		 3d2tB-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		5 / 12 GLN A 298
MET A  59
LEU A  83
ILE A  87
THR A  72
 None
 1.28A 3elzA-3mmtA:
undetectable		 3elzA-3mmtA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		5 / 12 GLN A 298
MET A  59
LEU A  83
ILE A  87
THR A  72
 None
 1.33A 3em0B-3mmtA:
undetectable		 3em0B-3mmtA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		5 / 12 ILE A 176
MET A  59
LEU A  83
ILE A  87
THR A  72
 None
 1.30A 3em0B-3mmtA:
undetectable		 3em0B-3mmtA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		5 / 11 ILE A   8
ARG A   4
GLY A 172
ALA A 171
VAL A  98
 None
 1.14A 3rukD-3mmtA:
undetectable		 3rukD-3mmtA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		5 / 12 LEU A  52
PHE A  53
GLY A 294
GLU A  24
GLN A 298
 None
None
2FP  A 350 (-3.3A)
2FP  A 350 ( 4.9A)
None
 1.35A 3tbgC-3mmtA:
undetectable		 3tbgC-3mmtA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 7 LYS A 223
ALA A 261
LEU A  12
THR A 290
 2FP  A 350 (-2.2A)
None
None
None
 1.00A 4ikjA-3mmtA:
undetectable
4ikjB-3mmtA:
undetectable		 4ikjA-3mmtA:
15.70
4ikjB-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 8 GLY A  18
GLY A  16
LEU A 331
LEU A 328
 None
 0.75A 4mwzB-3mmtA:
undetectable		 4mwzB-3mmtA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		3 / 3 MET A   1
MET A 220
TYR A 128
 None
 1.42A 4p6xI-3mmtA:
undetectable		 4p6xI-3mmtA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		5 / 12 ILE A 221
GLY A  18
LEU A 276
HIS A 275
THR A 268
 None
 1.20A 4zdyA-3mmtA:
undetectable		 4zdyA-3mmtA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 8 ASN A 225
PRO A 224
PHE A 262
SER A 264
 None
None
None
2FP  A 350 (-2.3A)
 1.44A 5amiB-3mmtA:
undetectable		 5amiB-3mmtA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 6 LYS A 223
ALA A 261
LEU A  12
THR A 290
 2FP  A 350 (-2.2A)
None
None
None
 1.06A 5bojA-3mmtA:
undetectable		 5bojA-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		5 / 12 PHE A 207
VAL A 206
PRO A 179
PHE A 262
GLY A 265
 None
None
None
None
2FP  A 350 (-3.5A)
 1.35A 5f9zB-3mmtA:
undetectable		 5f9zB-3mmtA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 6 LYS A 223
ALA A 261
LEU A  12
THR A 290
 2FP  A 350 (-2.2A)
None
None
None
 0.99A 5l4iA-3mmtA:
undetectable		 5l4iA-3mmtA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 8 ILE A 221
VAL A 257
TRP A 287
THR A 252
 None
 0.79A 6cduD-3mmtA:
undetectable
6cduE-3mmtA:
undetectable		 6cduD-3mmtA:
20.00
6cduE-3mmtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 7 ILE A 221
VAL A 257
TRP A 287
THR A 252
 None
 0.74A 6cduF-3mmtA:
undetectable
6cduG-3mmtA:
undetectable		 6cduF-3mmtA:
20.00
6cduG-3mmtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 7 ASN A 280
ALA A 281
GLU A 239
LEU A 276
 None
 1.01A 6ci6A-3mmtA:
undetectable		 6ci6A-3mmtA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Bartonella
henselae) 		4 / 6 MET A  82
THR A  84
LEU A  86
LEU A  20
 None
 1.16A 6mvxA-3mmtA:
undetectable
6mvxB-3mmtA:
undetectable
6mvxC-3mmtA:
undetectable		 6mvxA-3mmtA:
21.45
6mvxB-3mmtA:
21.45
6mvxC-3mmtA:
21.45