SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 11 ILE A 124
LEU A  97
LEU A 129
GLY A 128
ALA A  20
 None
 1.06A 1b02A-3mn1A:
undetectable		 1b02A-3mn1A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		4 / 5 ILE A 147
LEU A 114
ALA A 156
GLU A 159
 None
 1.26A 1xvaA-3mn1A:
3.2
1xvaB-3mn1A:
3.5		 1xvaA-3mn1A:
22.34
1xvaB-3mn1A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 10 PHE A  22
VAL A  27
GLY A 152
VAL A  21
GLY A 115
 None
 1.07A 3km6A-3mn1A:
undetectable		 3km6A-3mn1A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		3 / 3 LYS A  99
ARG A  90
LYS A  79
 None
 1.33A 3okxA-3mn1A:
undetectable		 3okxA-3mn1A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		4 / 6 HIS A 145
GLY A 130
ALA A 112
GLU A 109
 None
 0.94A 4ae1A-3mn1A:
undetectable		 4ae1A-3mn1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 12 LEU A  19
ALA A  20
LEU A  56
GLY A  50
LEU A  28
 None
None
None
CL  A 188 ( 3.7A)
None
 1.01A 4dm8B-3mn1A:
undetectable		 4dm8B-3mn1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 11 ILE A  65
LEU A  97
LEU A 114
GLY A 115
ALA A 112
 None
 1.19A 4fogD-3mn1A:
undetectable		 4fogD-3mn1A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 12 LEU A  10
GLY A 130
ALA A 144
ILE A 147
ASP A  49
 None
 1.29A 4xe5A-3mn1A:
17.6		 4xe5A-3mn1A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 11 ILE A 124
LEU A  97
LEU A 129
GLY A 128
ALA A  20
 None
 1.10A 5fctA-3mn1A:
undetectable		 5fctA-3mn1A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 12 LEU A 129
ILE A  65
THR A 148
ALA A 156
LEU A  28
 None
 1.32A 5ienA-3mn1A:
undetectable		 5ienA-3mn1A:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 9 VAL A  61
LEU A 171
ALA A 174
VAL A 177
SER A 176
 None
 1.33A 6c2mB-3mn1A:
undetectable		 6c2mB-3mn1A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 12 GLY A  31
VAL A 133
ARG A  32
GLU A 154
GLY A 153
 None
 1.24A 6gngA-3mn1A:
5.1		 6gngA-3mn1A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		4 / 8 ASP A  49
HIS A 175
GLU A 162
GLU A   2
 None
 1.26A 6mn4B-3mn1A:
undetectable		 6mn4B-3mn1A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 12 ILE A 124
LEU A  97
LEU A 129
GLY A 128
ALA A  20
 None
 1.13A 6r2eE-3mn1A:
undetectable		 6r2eE-3mn1A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 3mn1 PROBABLE YRBI FAMILY
PHOSPHATASE
(Pseudomonas
savastanoi) 		5 / 11 ILE A 124
LEU A  97
LEU A 129
GLY A 128
ALA A  20
 None
 1.17A 6r2eF-3mn1A:
undetectable		 6r2eF-3mn1A:
21.67