SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mn2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TCT_A_CTCA222_0
(TETRACYCLINE
REPRESSOR)		 3mn2 PROBABLE ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Rhodopseudomonas
palustris) 		5 / 12 SER A 295
PHE A 298
ARG A 309
PRO A 316
VAL A 289
 None
 1.40A 2tctA-3mn2A:
1.8		 2tctA-3mn2A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 3mn2 PROBABLE ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Rhodopseudomonas
palustris) 		4 / 5 PHE A 256
PHE A 267
ALA A 268
LEU A 241
 None
None
PO4  A   2 (-3.6A)
None
 1.02A 3t3zC-3mn2A:
undetectable		 3t3zC-3mn2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3mn2 PROBABLE ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Rhodopseudomonas
palustris) 		5 / 12 PHE A 253
PHE A 256
ILE A 236
TYR A 227
GLN A 223
 None
None
PO4  A   2 (-4.3A)
None
None
 1.29A 4a83A-3mn2A:
undetectable		 4a83A-3mn2A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 3mn2 PROBABLE ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Rhodopseudomonas
palustris) 		4 / 7 ASP A 282
SER A 281
TYR A 308
HIS A 277
 None
 1.34A 4arcA-3mn2A:
undetectable		 4arcA-3mn2A:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_B_377B401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3mn2 PROBABLE ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Rhodopseudomonas
palustris) 		4 / 5 GLU A 229
GLU A 225
TYR A 262
PHE A 256
 None
 1.48A 4twdA-3mn2A:
undetectable
4twdB-3mn2A:
undetectable		 4twdA-3mn2A:
15.81
4twdB-3mn2A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3mn2 PROBABLE ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Rhodopseudomonas
palustris) 		4 / 6 GLU A 229
GLU A 225
TYR A 262
PHE A 256
 None
 1.50A 4twdG-3mn2A:
undetectable
4twdH-3mn2A:
undetectable		 4twdG-3mn2A:
15.81
4twdH-3mn2A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3mn2 PROBABLE ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Rhodopseudomonas
palustris) 		5 / 12 ALA A 266
GLN A 223
LYS A 218
THR A 245
GLU A 229
 None
 1.38A 5hfjC-3mn2A:
undetectable		 5hfjC-3mn2A:
21.54