SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mn3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 213
CYH A 212
LEU A 260
PHE A 261
 None
 0.77A 1h4oG-3mn3A:
undetectable		 1h4oG-3mn3A:
21.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		6 / 9 LEU A  61
VAL A  69
ALA A  82
TYR A 134
ALA A 135
LEU A 184
 None
 0.90A 1muoA-3mn3A:
22.9		 1muoA-3mn3A:
32.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 162
ILE A 161
ILE A 115
ILE A 297
 None
 0.62A 2nniA-3mn3A:
undetectable		 2nniA-3mn3A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 282
ALA A 279
LEU A 246
MET A 245
ILE A 162
 None
 1.31A 3olsB-3mn3A:
undetectable		 3olsB-3mn3A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		7 / 12 VAL A  69
ALA A  82
LEU A 107
ILE A 116
TYR A 134
ALA A 135
ALA A 194
 None
 0.91A 3rgfA-3mn3A:
5.7		 3rgfA-3mn3A:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		4 / 5 ASP A 234
GLU A 232
GLY A 230
ASP A 177
 None
 1.39A 3w9tD-3mn3A:
undetectable		 3w9tD-3mn3A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 115
ILE A 116
MET A 130
TYR A 134
ILE A 193
 None
 0.65A 3zosA-3mn3A:
20.3		 3zosA-3mn3A:
29.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 110
ILE A 115
ILE A 116
TYR A 134
ILE A 193
 None
 0.52A 3zosA-3mn3A:
20.3		 3zosA-3mn3A:
29.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 9 LEU A  61
LEU A 110
ILE A 115
TYR A 134
ILE A 193
 None
 0.69A 3zosB-3mn3A:
14.3		 3zosB-3mn3A:
29.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 SER A 237
PHE A 306
ILE A 162
SER A 163
PHE A 158
 None
 1.48A 4c49B-3mn3A:
undetectable		 4c49B-3mn3A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		4 / 5 VAL A  69
ILE A 115
TYR A 134
ILE A 193
 None
 0.62A 4c8bA-3mn3A:
20.7		 4c8bA-3mn3A:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 9 LEU A  83
GLY A  53
ASN A  54
VAL A 131
VAL A  81
 None
 1.08A 4qd3A-3mn3A:
undetectable		 4qd3A-3mn3A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 242
ILE A 300
GLU A 151
LEU A 246
SER A 276
 None
 1.24A 4r88A-3mn3A:
undetectable		 4r88A-3mn3A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 242
ILE A 300
GLU A 151
LEU A 246
SER A 276
 None
 1.21A 4r88B-3mn3A:
undetectable		 4r88B-3mn3A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 242
ILE A 300
GLU A 151
LEU A 246
SER A 276
 None
 1.21A 4r88C-3mn3A:
undetectable		 4r88C-3mn3A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 242
ILE A 300
GLU A 151
LEU A 246
SER A 276
 None
 1.21A 4r88D-3mn3A:
undetectable		 4r88D-3mn3A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 242
ILE A 300
GLU A 151
LEU A 246
SER A 276
 None
 1.23A 4r88E-3mn3A:
undetectable		 4r88E-3mn3A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 242
ILE A 300
GLU A 151
LEU A 246
SER A 276
 None
 1.21A 4r88F-3mn3A:
undetectable		 4r88F-3mn3A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		6 / 9 LEU A  61
VAL A  69
ILE A 116
TYR A 134
LEU A 184
ILE A 193
 None
 0.97A 4v01A-3mn3A:
20.7		 4v01A-3mn3A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_B_0LIB1770_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		6 / 9 LEU A  61
VAL A  69
ILE A 116
TYR A 134
LEU A 184
ILE A 193
 None
 1.03A 4v01B-3mn3A:
20.5		 4v01B-3mn3A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 116
TYR A 134
LEU A 184
ILE A 193
 None
 0.60A 4v04A-3mn3A:
20.4		 4v04A-3mn3A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		6 / 10 LEU A  61
VAL A  69
ILE A 116
TYR A 134
LEU A 184
ILE A 193
 None
 0.90A 4v04B-3mn3A:
20.3		 4v04B-3mn3A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 176
ASP A 195
TYR A 106
 None
 0.85A 4yo9B-3mn3A:
undetectable		 4yo9B-3mn3A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 283
LEU A 282
GLU A 151
GLY A 278
GLY A 281
 None
 1.49A 5a06A-3mn3A:
undetectable		 5a06A-3mn3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 283
LEU A 282
GLU A 151
GLY A 278
GLY A 281
 None
 1.47A 5a06C-3mn3A:
undetectable		 5a06C-3mn3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 283
LEU A 282
GLU A 151
GLY A 278
GLY A 281
 None
 1.48A 5a06E-3mn3A:
undetectable		 5a06E-3mn3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 283
LEU A 282
GLU A 151
GLY A 278
GLY A 281
 None
 1.50A 5a06F-3mn3A:
undetectable		 5a06F-3mn3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 PRO A 251
ILE A 143
LEU A 250
ILE A 161
PHE A 140
 None
 1.17A 5tiwB-3mn3A:
undetectable		 5tiwB-3mn3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 278
SER A 276
LEU A 271
LEU A 287
ARG A 155
 None
 1.20A 5w7pA-3mn3A:
undetectable		 5w7pA-3mn3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 185
ILE A 143
HIS A 114
LEU A 314
TYR A 313
 None
 1.48A 5ycpA-3mn3A:
undetectable		 5ycpA-3mn3A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 176
PHE A 207
PHE A 196
 None
 1.02A 6nknC-3mn3A:
undetectable
6nknJ-3mn3A:
undetectable		 6nknC-3mn3A:
21.58
6nknJ-3mn3A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 162
LEU A 139
LEU A 242
GLY A 239
ALA A 154
 None
 1.26A 6r2eH-3mn3A:
undetectable		 6r2eH-3mn3A:
19.23