SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mn8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ILE A 125
ARG A 124
TYR A 117
PHE A  34
 None
 1.05A 1e71M-3mn8A:
undetectable		 1e71M-3mn8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ILE A 125
ARG A 124
TYR A 117
PHE A  34
 None
 1.08A 1e72M-3mn8A:
undetectable		 1e72M-3mn8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 8 ASP A 228
GLY A 288
GLY A 287
GLN A 290
 GEM  A 601 (-3.1A)
None
None
None
 0.86A 1ekjA-3mn8A:
undetectable
1ekjB-3mn8A:
undetectable		 1ekjA-3mn8A:
21.10
1ekjB-3mn8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 228
GLY A 288
GLY A 287
GLN A 290
 GEM  A 601 (-3.1A)
None
None
None
 0.91A 1ekjE-3mn8A:
undetectable
1ekjF-3mn8A:
undetectable		 1ekjE-3mn8A:
21.10
1ekjF-3mn8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 8 GLN A 290
ASP A 228
GLY A 288
GLY A 287
 None
GEM  A 601 (-3.1A)
None
None
 0.86A 1ekjE-3mn8A:
undetectable
1ekjF-3mn8A:
undetectable		 1ekjE-3mn8A:
21.10
1ekjF-3mn8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 8 ASP A 228
GLY A 288
GLY A 287
GLN A 290
 GEM  A 601 (-3.1A)
None
None
None
 0.85A 1ekjG-3mn8A:
undetectable
1ekjH-3mn8A:
undetectable		 1ekjG-3mn8A:
21.10
1ekjH-3mn8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		5 / 11 ASN A 161
SER A 151
GLY A 147
GLY A 102
ASP A 103
 None
 1.11A 1ho5A-3mn8A:
undetectable		 1ho5A-3mn8A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3mn8 LP15968P
(Drosophila
melanogaster) 		5 / 12 LEU A 128
LEU A 131
VAL A 132
SER A 134
LEU A 139
 None
 1.30A 1ie9A-3mn8A:
undetectable		 1ie9A-3mn8A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 3mn8 LP15968P
(Drosophila
melanogaster) 		5 / 11 PHE A 216
LEU A 110
VAL A 106
TYR A 255
TYR A  96
 None
 1.40A 1qabE-3mn8A:
undetectable		 1qabE-3mn8A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.43A 1v54A-3mn8A:
undetectable
1v54C-3mn8A:
undetectable		 1v54A-3mn8A:
23.47
1v54C-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.43A 1v54N-3mn8A:
undetectable
1v54P-3mn8A:
undetectable		 1v54N-3mn8A:
23.47
1v54P-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.45A 1v55A-3mn8A:
undetectable
1v55C-3mn8A:
undetectable		 1v55A-3mn8A:
23.47
1v55C-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.42A 2dyrA-3mn8A:
undetectable
2dyrC-3mn8A:
undetectable		 2dyrA-3mn8A:
23.47
2dyrC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.42A 2dyrN-3mn8A:
undetectable
2dyrP-3mn8A:
undetectable		 2dyrN-3mn8A:
23.47
2dyrP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.46A 2dysA-3mn8A:
undetectable
2dysC-3mn8A:
undetectable		 2dysA-3mn8A:
23.47
2dysC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 2dysN-3mn8A:
undetectable
2dysP-3mn8A:
undetectable		 2dysN-3mn8A:
23.47
2dysP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.45A 2eijA-3mn8A:
undetectable
2eijC-3mn8A:
undetectable		 2eijA-3mn8A:
23.47
2eijC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 2eijN-3mn8A:
undetectable
2eijP-3mn8A:
undetectable		 2eijN-3mn8A:
23.47
2eijP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.46A 2eikA-3mn8A:
undetectable
2eikC-3mn8A:
undetectable		 2eikA-3mn8A:
23.47
2eikC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 2eikN-3mn8A:
undetectable
2eikP-3mn8A:
undetectable		 2eikN-3mn8A:
23.47
2eikP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.45A 2eilA-3mn8A:
undetectable
2eilC-3mn8A:
undetectable		 2eilA-3mn8A:
23.47
2eilC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.42A 2eilN-3mn8A:
undetectable
2eilP-3mn8A:
undetectable		 2eilN-3mn8A:
23.47
2eilP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.47A 2eimA-3mn8A:
undetectable
2eimC-3mn8A:
undetectable		 2eimA-3mn8A:
23.47
2eimC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.46A 2eimN-3mn8A:
undetectable
2eimP-3mn8A:
undetectable		 2eimN-3mn8A:
23.47
2eimP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.43A 2einA-3mn8A:
undetectable
2einC-3mn8A:
undetectable		 2einA-3mn8A:
23.47
2einC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.48A 2einN-3mn8A:
undetectable
2einP-3mn8A:
undetectable		 2einN-3mn8A:
23.47
2einP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 5 MET A 262
PRO A 260
ASN A 324
LEU A 306
 None
 1.26A 2wekA-3mn8A:
0.0		 2wekA-3mn8A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 MET A 262
PRO A 260
ASN A 324
LEU A 306
 None
 1.22A 2wekB-3mn8A:
undetectable		 2wekB-3mn8A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ILE A 205
TYR A 138
TRP A 204
CYH A 299
 None
 1.30A 2xz5D-3mn8A:
undetectable
2xz5E-3mn8A:
undetectable		 2xz5D-3mn8A:
18.62
2xz5E-3mn8A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.42A 2y69A-3mn8A:
undetectable
2y69C-3mn8A:
undetectable		 2y69A-3mn8A:
23.47
2y69C-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		3 / 3 ASP A 413
PHE A 414
LEU A 416
 None
 0.69A 2zi9A-3mn8A:
2.4		 2zi9A-3mn8A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.46A 2zxwA-3mn8A:
undetectable
2zxwC-3mn8A:
undetectable		 2zxwA-3mn8A:
23.47
2zxwC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 2zxwN-3mn8A:
undetectable
2zxwP-3mn8A:
undetectable		 2zxwN-3mn8A:
23.47
2zxwP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.46A 3abkA-3mn8A:
undetectable
3abkC-3mn8A:
undetectable		 3abkA-3mn8A:
23.47
3abkC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.43A 3abkN-3mn8A:
undetectable
3abkP-3mn8A:
undetectable		 3abkN-3mn8A:
23.47
3abkP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.42A 3abmN-3mn8A:
undetectable
3abmP-3mn8A:
undetectable		 3abmN-3mn8A:
23.47
3abmP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.49A 3ag1A-3mn8A:
undetectable
3ag1C-3mn8A:
undetectable		 3ag1A-3mn8A:
23.47
3ag1C-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.43A 3ag1N-3mn8A:
undetectable
3ag1P-3mn8A:
undetectable		 3ag1N-3mn8A:
23.47
3ag1P-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.47A 3ag2A-3mn8A:
undetectable
3ag2C-3mn8A:
undetectable		 3ag2A-3mn8A:
23.47
3ag2C-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.45A 3ag2N-3mn8A:
undetectable
3ag2P-3mn8A:
undetectable		 3ag2N-3mn8A:
23.47
3ag2P-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.47A 3ag3A-3mn8A:
undetectable
3ag3C-3mn8A:
undetectable		 3ag3A-3mn8A:
23.47
3ag3C-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 3ag3N-3mn8A:
undetectable
3ag3P-3mn8A:
undetectable		 3ag3N-3mn8A:
23.47
3ag3P-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.48A 3ag4A-3mn8A:
undetectable
3ag4C-3mn8A:
undetectable		 3ag4A-3mn8A:
23.47
3ag4C-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 3ag4N-3mn8A:
undetectable
3ag4P-3mn8A:
undetectable		 3ag4N-3mn8A:
23.47
3ag4P-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 3asnA-3mn8A:
undetectable
3asnC-3mn8A:
undetectable		 3asnA-3mn8A:
23.47
3asnC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 3mn8 LP15968P
(Drosophila
melanogaster) 		3 / 3 TYR A 283
ASP A 270
HIS A 217
 GEM  A 601 (-3.3A)
None
ZN  A 999 ( 3.2A)
 0.79A 3e23A-3mn8A:
undetectable		 3e23A-3mn8A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		3 / 3 HIS A 101
HIS A 217
MET A 100
 ZN  A 999 ( 3.0A)
ZN  A 999 ( 3.2A)
None
 0.95A 3mihA-3mn8A:
undetectable		 3mihA-3mn8A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3mn8 LP15968P
(Drosophila
melanogaster) 		3 / 3 LYS A  62
ARG A  85
LYS A 370
 None
 1.37A 3okxA-3mn8A:
undetectable		 3okxA-3mn8A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 GLN A  79
TYR A 138
PHE A 210
PRO A  93
 None
 1.07A 3tgvB-3mn8A:
undetectable		 3tgvB-3mn8A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 GLN A  79
TYR A 138
PHE A 210
PRO A  93
 None
 1.05A 3tgvD-3mn8A:
undetectable		 3tgvD-3mn8A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 3mn8 LP15968P
(Drosophila
melanogaster) 		3 / 3 SER A 224
PHE A 248
LYS A 249
 GEM  A 601 ( 4.2A)
None
None
 0.82A 3u88A-3mn8A:
undetectable		 3u88A-3mn8A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 5 LEU A 285
GLY A 279
THR A 277
VAL A 222
 GEM  A 601 (-4.0A)
GEM  A 601 (-3.3A)
None
None
 1.04A 3wrkD-3mn8A:
undetectable		 3wrkD-3mn8A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 GLY A 147
PRO A 145
ASN A 144
GLY A  72
 None
 0.85A 4fjpA-3mn8A:
undetectable		 4fjpA-3mn8A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 3mn8 LP15968P
(Drosophila
melanogaster) 		5 / 7 GLY A 102
TYR A  40
SER A 151
TYR A 148
GLU A 153
 None
 1.48A 4hyfA-3mn8A:
undetectable		 4hyfA-3mn8A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 3mn8 LP15968P
(Drosophila
melanogaster) 		5 / 8 GLY A 102
TYR A  40
SER A 151
TYR A 148
GLU A 153
 None
 1.49A 4hyfB-3mn8A:
undetectable		 4hyfB-3mn8A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 5 LEU A 251
SER A 213
LEU A 332
LEU A 377
 None
 1.13A 4n09B-3mn8A:
2.4		 4n09B-3mn8A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 5 CYH A 299
SER A 213
LEU A 332
LEU A 377
 None
 1.27A 4n09D-3mn8A:
2.4		 4n09D-3mn8A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 5 LEU A 251
SER A 213
LEU A 332
LEU A 377
 None
 1.13A 4n09D-3mn8A:
2.4		 4n09D-3mn8A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		3 / 3 VAL A 206
PHE A 177
ARG A 194
 None
 0.79A 4xr4B-3mn8A:
undetectable		 4xr4B-3mn8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 5 GLY A 166
ARG A 165
GLY A 102
GLU A 104
 None
GEM  A 601 (-3.2A)
None
ZN  A 999 ( 1.7A)
 1.24A 4z2eB-3mn8A:
undetectable
4z2eC-3mn8A:
3.3		 4z2eB-3mn8A:
21.67
4z2eC-3mn8A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 5 ALA A  41
TYR A  40
HIS A 259
PRO A 318
 None
 1.03A 4ze2A-3mn8A:
undetectable		 4ze2A-3mn8A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mn8 LP15968P
(Drosophila
melanogaster) 		3 / 3 THR A 379
HIS A 281
LEU A 241
 None
 0.74A 5axdA-3mn8A:
2.5		 5axdA-3mn8A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 5b1aN-3mn8A:
undetectable
5b1aP-3mn8A:
undetectable		 5b1aN-3mn8A:
23.47
5b1aP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.45A 5b1bN-3mn8A:
undetectable
5b1bP-3mn8A:
undetectable		 5b1bN-3mn8A:
23.47
5b1bP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 5b3sN-3mn8A:
undetectable
5b3sP-3mn8A:
undetectable		 5b3sN-3mn8A:
23.47
5b3sP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 5iy5A-3mn8A:
undetectable
5iy5C-3mn8A:
undetectable		 5iy5A-3mn8A:
23.47
5iy5C-3mn8A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 4 VAL A 358
VAL A 385
TYR A 383
GLN A 399
 None
 1.28A 5qggA-3mn8A:
undetectable		 5qggA-3mn8A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 4 VAL A 358
VAL A 385
TYR A 383
GLN A 399
 None
 1.23A 5qgoA-3mn8A:
undetectable		 5qgoA-3mn8A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 4 VAL A 358
VAL A 385
TYR A 383
GLN A 399
 None
 1.25A 5qgpA-3mn8A:
undetectable		 5qgpA-3mn8A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 4 VAL A 358
VAL A 385
TYR A 383
GLN A 399
 None
 1.27A 5qhbA-3mn8A:
undetectable		 5qhbA-3mn8A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 5 LEU A  46
LEU A  76
GLN A 109
TYR A  40
 None
 1.42A 5uc3A-3mn8A:
undetectable		 5uc3A-3mn8A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.45A 5x19N-3mn8A:
undetectable
5x19P-3mn8A:
undetectable		 5x19N-3mn8A:
23.47
5x19P-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.48A 5x1bN-3mn8A:
undetectable
5x1bP-3mn8A:
undetectable		 5x1bN-3mn8A:
23.47
5x1bP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.50A 5x1fN-3mn8A:
undetectable
5x1fP-3mn8A:
undetectable		 5x1fN-3mn8A:
23.47
5x1fP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 5zcqN-3mn8A:
undetectable
5zcqP-3mn8A:
undetectable		 5zcqN-3mn8A:
23.47
5zcqP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.42A 6nknA-3mn8A:
undetectable
6nknC-3mn8A:
undetectable		 6nknA-3mn8A:
23.47
6nknC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.46A 6nmfN-3mn8A:
undetectable
6nmfP-3mn8A:
undetectable		 6nmfN-3mn8A:
23.47
6nmfP-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 6 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.42A 6nmpA-3mn8A:
undetectable
6nmpC-3mn8A:
undetectable		 6nmpA-3mn8A:
23.47
6nmpC-3mn8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mn8 LP15968P
(Drosophila
melanogaster) 		4 / 7 ASP A 257
THR A 254
TYR A 255
HIS A 336
 None
 1.44A 6nmpN-3mn8A:
undetectable
6nmpP-3mn8A:
undetectable		 6nmpN-3mn8A:
23.47
6nmpP-3mn8A:
19.95