SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 GLU A 208
GLU A 201
TYR A 452
GLY A 387
TYR A 457
 None
 1.07A 1httC-3mogA:
2.7		 1httC-3mogA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A 140
PHE A 189
GLY A 158
THR A 118
VAL A 155
 None
 1.14A 1pwyE-3mogA:
undetectable		 1pwyE-3mogA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ILE A 390
THR A 393
LEU A 220
VAL A 352
THR A 353
 None
 1.22A 1tw4A-3mogA:
undetectable		 1tw4A-3mogA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.17A 1utdT-3mogA:
undetectable
1utdU-3mogA:
undetectable		 1utdT-3mogA:
9.19
1utdU-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A 140
PHE A 189
GLY A 158
THR A 118
VAL A 155
 None
 1.24A 1v3qE-3mogA:
undetectable		 1v3qE-3mogA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 ALA A  21
ILE A  20
VAL A   8
ALA A  85
LEU A 115
 None
 1.04A 1xp0A-3mogA:
undetectable		 1xp0A-3mogA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 ILE A 397
PHE A 226
GLY A 428
ILE A 415
 None
 0.93A 2qwxA-3mogA:
5.1
2qwxB-3mogA:
5.1		 2qwxA-3mogA:
19.88
2qwxB-3mogA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 TRP A 391
GLN A 326
TRP A 438
 None
 1.26A 2vqyA-3mogA:
undetectable		 2vqyA-3mogA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 7 LEU A 372
ILE A 344
GLN A 326
ALA A 395
ILE A 441
 None
 1.47A 2xkwA-3mogA:
undetectable		 2xkwA-3mogA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ILE A 382
THR A 325
THR A 353
VAL A 215
ILE A 216
 None
 1.17A 2yzqA-3mogA:
undetectable		 2yzqA-3mogA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A 372
ALA A 368
ALA A 364
PRO A 361
VAL A 359
 None
 1.14A 3cwkA-3mogA:
undetectable		 3cwkA-3mogA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 LEU A 152
SER A 411
GLY A 428
PRO A 429
 None
 1.00A 3hcrA-3mogA:
2.7		 3hcrA-3mogA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 SER A  37
LEU A  82
ILE A  11
SER A  13
GLY A  12
 None
 1.12A 3ijxB-3mogA:
undetectable
3ijxD-3mogA:
undetectable		 3ijxB-3mogA:
20.04
3ijxD-3mogA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 SER A  37
LEU A  82
ILE A  11
SER A  13
GLY A  12
 None
 1.19A 3iluB-3mogA:
undetectable
3iluE-3mogA:
undetectable		 3iluB-3mogA:
20.04
3iluE-3mogA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ILE A  11
SER A  13
GLY A  12
SER A  37
LEU A  82
 None
 1.16A 3iluB-3mogA:
undetectable
3iluE-3mogA:
undetectable		 3iluB-3mogA:
20.04
3iluE-3mogA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 VAL A 379
VAL A 343
ILE A 382
ARG A 366
 None
 1.06A 3ms9B-3mogA:
undetectable		 3ms9B-3mogA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		4 / 6 PRO A 386
GLY A 387
LEU A 444
ASN A 447
 None
 0.93A 3zqtA-3mogA:
undetectable		 3zqtA-3mogA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 PRO A 230
LEU A 231
GLN A 265
 None
 0.67A 4pevB-3mogA:
4.5		 4pevB-3mogA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 GLY A 225
PHE A 226
ASP A 217
GLY A 229
TYR A 198
 None
 1.26A 4qa0A-3mogA:
undetectable		 4qa0A-3mogA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 GLU A  39
LEU A  33
GLY A  14
ALA A  18
ILE A  48
 None
 1.25A 4xe5A-3mogA:
3.2		 4xe5A-3mogA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 ILE A 354
GLY A 294
ILE A 369
LEU A 380
 None
 0.93A 5dzkd-3mogA:
undetectable
5dzkk-3mogA:
undetectable
5dzky-3mogA:
undetectable		 5dzkd-3mogA:
19.58
5dzkk-3mogA:
21.38
5dzky-3mogA:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 ILE A 397
ALA A 418
VAL A 423
TYR A 425
 None
 0.87A 5ecnD-3mogA:
undetectable		 5ecnD-3mogA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.19A 5eeuO-3mogA:
undetectable
5eeuP-3mogA:
undetectable		 5eeuO-3mogA:
9.19
5eeuP-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.20A 5eeuQ-3mogA:
undetectable
5eeuR-3mogA:
undetectable		 5eeuQ-3mogA:
9.19
5eeuR-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.19A 5eevO-3mogA:
undetectable
5eevP-3mogA:
undetectable		 5eevO-3mogA:
9.19
5eevP-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.20A 5eevQ-3mogA:
undetectable
5eevR-3mogA:
undetectable		 5eevQ-3mogA:
9.19
5eevR-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.19A 5eewO-3mogA:
undetectable
5eewP-3mogA:
undetectable		 5eewO-3mogA:
9.19
5eewP-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.19A 5eexO-3mogA:
undetectable
5eexP-3mogA:
undetectable		 5eexO-3mogA:
9.19
5eexP-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.19A 5eeyO-3mogA:
undetectable
5eeyP-3mogA:
undetectable		 5eeyO-3mogA:
9.19
5eeyP-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.19A 5eezO-3mogA:
undetectable
5eezP-3mogA:
undetectable		 5eezO-3mogA:
9.19
5eezP-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.19A 5ef0O-3mogA:
undetectable
5ef0P-3mogA:
undetectable		 5ef0O-3mogA:
9.19
5ef0P-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.19A 5ef1O-3mogA:
undetectable
5ef1P-3mogA:
undetectable		 5ef1O-3mogA:
9.19
5ef1P-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.19A 5ef2O-3mogA:
undetectable
5ef2P-3mogA:
undetectable		 5ef2O-3mogA:
9.19
5ef2P-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  19
ALA A  24
ILE A  20
SER A  26
ALA A  25
 None
 1.20A 5ef3O-3mogA:
undetectable
5ef3P-3mogA:
undetectable		 5ef3O-3mogA:
9.19
5ef3P-3mogA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ASN A 192
SER A 121
SER A 122
 None
 0.46A 5gsnA-3mogA:
undetectable		 5gsnA-3mogA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 VAL A 155
GLN A 168
CYH A 170
 None
 0.80A 5icxA-3mogA:
undetectable
5icxE-3mogA:
undetectable		 5icxA-3mogA:
19.87
5icxE-3mogA:
3.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 VAL A 394
THR A 393
ILE A 397
GLY A 225
ALA A 224
 None
 1.04A 5mxbA-3mogA:
undetectable		 5mxbA-3mogA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ILE A 125
VAL A 166
SER A 157
ILE A 132
ALA A 129
 None
 1.16A 5n0sB-3mogA:
undetectable		 5n0sB-3mogA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 ILE A  11
GLY A  12
GLY A  17
VAL A  31
LEU A  32
 None
 0.98A 5o96C-3mogA:
2.8
5o96D-3mogA:
2.6		 5o96C-3mogA:
21.00
5o96D-3mogA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 TYR A 199
GLN A 239
ASP A 235
TYR A 425
 None
 1.25A 5ov9B-3mogA:
undetectable		 5ov9B-3mogA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 VAL A  31
LEU A  73
VAL A  10
GLY A  17
ILE A  20
 None
 1.07A 5vopA-3mogA:
undetectable		 5vopA-3mogA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 VAL A 394
PRO A 426
GLY A 428
TYR A 425
 None
 1.30A 5x80A-3mogA:
undetectable
5x80B-3mogA:
undetectable		 5x80A-3mogA:
16.91
5x80B-3mogA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 PRO A 426
GLY A 428
TYR A 425
VAL A 394
 None
 1.30A 5x80C-3mogA:
undetectable
5x80D-3mogA:
undetectable		 5x80C-3mogA:
16.91
5x80D-3mogA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		4 / 4 GLY A 422
LEU A 152
VAL A 191
GLU A 154
 None
 1.31A 5yw0A-3mogA:
undetectable		 5yw0A-3mogA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 3mog PROBABLE
3-HYDROXYBUTYRYL-COA
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 TYR A  34
ALA A  92
LEU A 102
 None
 0.56A 6d9kF-3mogA:
undetectable		 6d9kF-3mogA:
21.80