SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3moi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		3 / 3 GLN A 341
ILE A 352
HIS A  90
 None
 0.74A 1k74A-3moiA:
undetectable		 1k74A-3moiA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		3 / 3 ASP A 155
ARG A 159
ASP A 239
 None
 0.82A 1vptA-3moiA:
2.8		 1vptA-3moiA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		3 / 3 LEU A 304
LEU A 218
MET A 217
 None
 0.74A 2itzA-3moiA:
undetectable		 2itzA-3moiA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KI5_B_AC2B2_1
(PROTEIN (THYMIDINE
KINASE))		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 12 HIS A 126
GLU A  94
ILE A  92
ILE A 345
MET A  18
 None
 1.40A 2ki5B-3moiA:
0.0		 2ki5B-3moiA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		4 / 5 PRO A  26
ILE A 345
ARG A 349
ASP A 346
 None
 1.42A 2rhmB-3moiA:
undetectable		 2rhmB-3moiA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		4 / 5 PRO A  26
ILE A 345
ARG A 349
ASP A 346
 None
 1.38A 2rhmD-3moiA:
undetectable		 2rhmD-3moiA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		4 / 8 LEU A  56
ALA A  67
LEU A  89
MET A  65
 None
 0.89A 3cldB-3moiA:
undetectable		 3cldB-3moiA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 9 GLY A 365
VAL A 120
ASP A 184
ILE A 183
VAL A 371
 None
 1.43A 3fi0D-3moiA:
undetectable		 3fi0D-3moiA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 9 GLY A 365
VAL A 120
ASP A 184
ILE A 183
VAL A 371
 None
 1.45A 3fi0K-3moiA:
undetectable		 3fi0K-3moiA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 9 GLY A 365
VAL A 120
ASP A 184
ILE A 183
VAL A 371
 None
 1.44A 3fi0N-3moiA:
undetectable		 3fi0N-3moiA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 9 GLY A 365
VAL A 120
ASP A 184
ILE A 183
VAL A 371
 None
 1.37A 3fi0R-3moiA:
undetectable		 3fi0R-3moiA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		4 / 7 VAL A  93
LEU A  17
MET A  18
ILE A  70
 None
 0.99A 3gp0A-3moiA:
undetectable		 3gp0A-3moiA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 12 LEU A 369
HIS A 181
PRO A  96
GLY A 121
THR A 122
 None
 1.22A 3okxB-3moiA:
undetectable		 3okxB-3moiA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		3 / 3 ARG A 336
MET A   1
ARG A 349
 None
 1.36A 3uvvA-3moiA:
undetectable		 3uvvA-3moiA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		4 / 8 TYR A 230
CYH A 214
VAL A 371
ILE A 175
 None
 1.03A 4aftD-3moiA:
undetectable
4aftE-3moiA:
undetectable		 4aftD-3moiA:
20.16
4aftE-3moiA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		3 / 3 ASP A 155
ARG A 159
ASP A 239
 None
 0.78A 4fzvA-3moiA:
undetectable		 4fzvA-3moiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		3 / 3 TYR A  48
HIS A  24
ARG A  23
 None
 1.10A 4htfA-3moiA:
5.7		 4htfA-3moiA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		4 / 7 GLU A 347
THR A 344
HIS A  77
LEU A  97
 None
 0.97A 4pfjA-3moiA:
4.2		 4pfjA-3moiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 10 TYR A 278
LEU A 273
GLY A 258
ALA A 259
LEU A 263
 None
 1.12A 4ph9A-3moiA:
undetectable		 4ph9A-3moiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 12 TYR A 278
LEU A 273
GLY A 258
ALA A 259
LEU A 263
 None
 1.12A 5jvzB-3moiA:
undetectable		 5jvzB-3moiA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		4 / 8 ARG A 295
PRO A 128
GLY A 335
ASP A 343
 None
 0.95A 5kf8A-3moiA:
undetectable		 5kf8A-3moiA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		4 / 8 ARG A 295
PRO A 128
GLY A 335
ASP A 343
 None
 0.94A 5kgpA-3moiA:
undetectable		 5kgpA-3moiA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		4 / 8 ARG A 295
PRO A 128
GLY A 335
ASP A 343
 None
 1.00A 5kgpB-3moiA:
undetectable		 5kgpB-3moiA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 9 GLY A 365
VAL A 120
ASP A 184
ILE A 183
VAL A 371
 None
 1.41A 5v0iA-3moiA:
undetectable		 5v0iA-3moiA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 9 GLY A 365
VAL A 120
ASP A 184
ILE A 183
VAL A 371
 None
 1.38A 5v0iB-3moiA:
undetectable		 5v0iB-3moiA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 11 VAL A 142
GLY A 143
GLU A 308
ALA A 310
LEU A 312
 None
 1.20A 5x6yA-3moiA:
2.3		 5x6yA-3moiA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 10 VAL A 142
GLY A 143
GLU A 308
ALA A 310
LEU A 312
 None
 1.17A 5x6yB-3moiA:
2.6		 5x6yB-3moiA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 11 VAL A 142
GLY A 143
GLU A 308
ALA A 310
LEU A 312
 None
 1.09A 5x6yC-3moiA:
2.0		 5x6yC-3moiA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		3 / 3 GLN A 341
ILE A 352
HIS A  90
 None
 0.71A 5z12B-3moiA:
undetectable		 5z12B-3moiA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		3 / 3 ASP A 155
ARG A 159
ASP A 239
 None
 0.88A 5zvgA-3moiA:
4.3		 5zvgA-3moiA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 3moi PROBABLE
DEHYDROGENASE
(Bordetella
bronchiseptica) 		5 / 9 VAL A 111
ALA A 114
VAL A  81
SER A  85
GLY A  88
 None
 1.28A 6bklA-3moiA:
undetectable
6bklB-3moiA:
undetectable
6bklC-3moiA:
undetectable
6bklD-3moiA:
undetectable		 6bklA-3moiA:
6.56
6bklB-3moiA:
6.56
6bklC-3moiA:
6.56
6bklD-3moiA:
6.56