SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3moj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU9_A_ACTA311_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	3moj	ATP-DEPENDENT RNA HELICASE DBPA (Bacillus subtilis)	3 / 3	GLN B 471 THR B 465 THR B 466	None None C A2556 ( 3.9A)	0.80A	4fu9A-3mojB: undetectable	4fu9A-3mojB: 15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FUF_A_ACTA310_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	3moj	ATP-DEPENDENT RNA HELICASE DBPA (Bacillus subtilis)	3 / 3	GLN B 471 THR B 465 THR B 466	None None C A2556 ( 3.9A)	0.78A	4fufA-3mojB: undetectable	4fufA-3mojB: 15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I73_A_68PA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	3moj	ATP-DEPENDENT RNA HELICASE DBPA (Bacillus subtilis)	5 / 12	ILE B 416 GLY B 423 PHE B 421 GLY B 469 VAL B 467	None U A2554 ( 3.5A) None C A2556 ( 3.1A) U A2555 ( 3.9A)	0.99A	5i73A-3mojB: undetectable	5i73A-3mojB: 9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I75_A_68PA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	3moj	ATP-DEPENDENT RNA HELICASE DBPA (Bacillus subtilis)	5 / 12	ILE B 416 GLY B 423 PHE B 421 GLY B 469 VAL B 467	None U A2554 ( 3.5A) None C A2556 ( 3.1A) U A2555 ( 3.9A)	0.98A	5i75A-3mojB: undetectable	5i75A-3mojB: 9.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4FU9_A_ACTA311_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","3moj","ATP-DEPENDENT RNA HELICASE DBPA","Bacillus subtilis",3,"GLN B 471;THR B 465;THR B 466","None;None;  C A2556 ( 3.9A)","0.80A","4fu9A-3mojB:undetectable","4fu9A-3mojB:15.45"],["4FUF_A_ACTA310_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","3moj","ATP-DEPENDENT RNA HELICASE DBPA","Bacillus subtilis",3,"GLN B 471;THR B 465;THR B 466","None;None;  C A2556 ( 3.9A)","0.78A","4fufA-3mojB:undetectable","4fufA-3mojB:15.45"],["5I73_A_68PA701_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","3moj","ATP-DEPENDENT RNA HELICASE DBPA","Bacillus subtilis",5,"ILE B 416;GLY B 423;PHE B 421;GLY B 469;VAL B 467","None;  U A2554 ( 3.5A);None;  C A2556 ( 3.1A);  U A2555 ( 3.9A)","0.99A","5i73A-3mojB:undetectable","5i73A-3mojB:9.71"],["5I75_A_68PA701_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","3moj","ATP-DEPENDENT RNA HELICASE DBPA","Bacillus subtilis",5,"ILE B 416;GLY B 423;PHE B 421;GLY B 469;VAL B 467","None;  U A2554 ( 3.5A);None;  C A2556 ( 3.1A);  U A2555 ( 3.9A)","0.98A","5i75A-3mojB:undetectable","5i75A-3mojB:9.71"]]