SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3moz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		3 / 3 GLN A 161
TYR A 216
ARG A 215
 None
 0.96A 1gtbA-3mozA:
undetectable		 1gtbA-3mozA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		5 / 11 SER A 106
ASN A  69
ARG A  68
GLY A 288
THR A 260
 GOL  A1007 ( 3.9A)
None
5IP  A 401 (-3.9A)
None
None
 1.19A 1jr1A-3mozA:
undetectable		 1jr1A-3mozA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		5 / 12 SER A  73
PHE A 250
TYR A 239
VAL A 323
ASN A 271
 None
None
GOL  A1001 (-4.0A)
None
None
 1.42A 1x70A-3mozA:
undetectable		 1x70A-3mozA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		3 / 3 THR A 259
GLU A 136
HIS A 224
 PO4  A 400 (-3.8A)
None
5IP  A 401 (-3.8A)
 0.73A 1xwfA-3mozA:
undetectable		 1xwfA-3mozA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		3 / 3 THR A 259
GLU A 136
HIS A 224
 PO4  A 400 (-3.8A)
None
5IP  A 401 (-3.8A)
 0.77A 1xwfB-3mozA:
undetectable		 1xwfB-3mozA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		3 / 3 THR A 259
GLU A 136
HIS A 224
 PO4  A 400 (-3.8A)
None
5IP  A 401 (-3.8A)
 0.79A 1xwfC-3mozA:
undetectable		 1xwfC-3mozA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		3 / 3 THR A 259
GLU A 136
HIS A 224
 PO4  A 400 (-3.8A)
None
5IP  A 401 (-3.8A)
 0.76A 1xwfD-3mozA:
undetectable		 1xwfD-3mozA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 6 TYR A 216
GLY A 104
PHE A 250
SER A 103
 None
 1.37A 2a3cA-3mozA:
undetectable		 2a3cA-3mozA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 6 TYR A 216
GLY A 104
PHE A 250
SER A 103
 None
 1.31A 2a3cB-3mozA:
undetectable		 2a3cB-3mozA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 8 LEU A  86
GLU A 317
LEU A 280
HIS A 284
 None
 0.95A 2azxA-3mozA:
undetectable		 2azxA-3mozA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		3 / 3 LYS A 312
ASP A 153
ASP A  59
 5IP  A 401 (-3.0A)
5IP  A 401 ( 4.9A)
None
 1.13A 2br4A-3mozA:
undetectable		 2br4A-3mozA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 5 ASN A 231
ALA A 221
ALA A 220
ARG A 218
 None
 1.49A 3kp2B-3mozA:
undetectable		 3kp2B-3mozA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		3 / 3 ARG A 282
ARG A  94
ILE A 279
 None
 0.91A 4b7qC-3mozA:
undetectable		 4b7qC-3mozA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 8 ASP A 153
ASP A 132
GLU A 253
GLU A 168
 5IP  A 401 ( 4.9A)
None
None
None
 1.02A 4gkhC-3mozA:
undetectable
4gkhK-3mozA:
undetectable		 4gkhC-3mozA:
20.85
4gkhK-3mozA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 8 ASP A 153
ASP A 132
GLU A 253
GLU A 168
 5IP  A 401 ( 4.9A)
None
None
None
 1.03A 4gkiE-3mozA:
undetectable
4gkiG-3mozA:
undetectable		 4gkiE-3mozA:
20.85
4gkiG-3mozA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 7 ASP A 132
GLU A 205
HIS A 251
VAL A 208
 None
 1.09A 4hvrA-3mozA:
undetectable		 4hvrA-3mozA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		3 / 3 ARG A 258
GLN A 135
GLU A 136
 PO4  A 400 (-3.9A)
None
None
 0.86A 4tvtA-3mozA:
undetectable		 4tvtA-3mozA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		5 / 12 VAL A 180
TRP A  56
ASP A 142
ILE A 144
GLY A 143
 None
 1.02A 4y8wA-3mozA:
undetectable		 4y8wA-3mozA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		5 / 12 VAL A 180
TRP A  56
ASP A 142
ILE A 144
GLY A 143
 None
 1.01A 4y8wB-3mozA:
undetectable		 4y8wB-3mozA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 5 LEU A 113
LYS A 114
ALA A 117
LEU A 120
 None
None
GOL  A1004 (-3.6A)
None
 0.84A 5vkqA-3mozA:
undetectable
5vkqD-3mozA:
undetectable		 5vkqA-3mozA:
11.14
5vkqD-3mozA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 5 LEU A 113
LYS A 114
ALA A 117
LEU A 120
 None
None
GOL  A1004 (-3.6A)
None
 0.83A 5vkqA-3mozA:
undetectable
5vkqB-3mozA:
undetectable		 5vkqA-3mozA:
11.14
5vkqB-3mozA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 5 LEU A 113
LYS A 114
ALA A 117
LEU A 120
 None
None
GOL  A1004 (-3.6A)
None
 0.83A 5vkqB-3mozA:
undetectable
5vkqC-3mozA:
undetectable		 5vkqB-3mozA:
11.14
5vkqC-3mozA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 5 LEU A 113
LYS A 114
ALA A 117
LEU A 120
 None
None
GOL  A1004 (-3.6A)
None
 0.83A 5vkqC-3mozA:
undetectable
5vkqD-3mozA:
undetectable		 5vkqC-3mozA:
11.14
5vkqD-3mozA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 6 ASP A  59
TYR A 140
GLU A 205
ASP A 132
 None
 1.12A 6mn5A-3mozA:
undetectable		 6mn5A-3mozA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE
(Selenomonas
ruminantium) 		4 / 7 ASP A  59
TYR A 140
GLU A 205
ASP A 132
 None
 1.19A 6mn5B-3mozA:
undetectable		 6mn5B-3mozA:
14.66