SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mp2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 3mp2 NON-STRUCTURAL
PROTEIN 3
(Alphacoronavirus
1) 		3 / 3 ASP A  29
PHE A  14
ARG A  75
 None
 0.80A 2a3aA-3mp2A:
undetectable		 2a3aA-3mp2A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 3mp2 NON-STRUCTURAL
PROTEIN 3
(Alphacoronavirus
1) 		5 / 11 LEU A  25
ILE A  34
LEU A  84
TYR A  68
GLY A  79
 None
 1.34A 2bxmA-3mp2A:
undetectable		 2bxmA-3mp2A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3mp2 NON-STRUCTURAL
PROTEIN 3
(Alphacoronavirus
1) 		4 / 8 HIS A 183
TYR A  39
LEU A  41
CYH A  37
 None
 1.04A 3lm8B-3mp2A:
undetectable
3lm8D-3mp2A:
undetectable		 3lm8B-3mp2A:
18.47
3lm8D-3mp2A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3mp2 NON-STRUCTURAL
PROTEIN 3
(Alphacoronavirus
1) 		3 / 3 SER A 148
ALA A 115
VAL A 116
 None
 0.48A 4o2bA-3mp2A:
undetectable		 4o2bA-3mp2A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3mp2 NON-STRUCTURAL
PROTEIN 3
(Alphacoronavirus
1) 		3 / 3 SER A 148
ALA A 115
VAL A 116
 None
 0.56A 4x1iA-3mp2A:
undetectable		 4x1iA-3mp2A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3mp2 NON-STRUCTURAL
PROTEIN 3
(Alphacoronavirus
1) 		3 / 3 SER A 148
ALA A 115
VAL A 116
 None
 0.54A 5eypA-3mp2A:
undetectable		 5eypA-3mp2A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3mp2 NON-STRUCTURAL
PROTEIN 3
(Alphacoronavirus
1) 		3 / 3 ASN A  65
ASP A  29
GLY A  76
 None
 0.67A 5fctB-3mp2A:
undetectable		 5fctB-3mp2A:
21.31