SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mpd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AFS_B_TESB325_1 (3-ALPHA-HYDROXYSTERO ID DEHYDROGENASE)	3mpd	NUCLEOSIDE DIPHOSPHATE KINASE (Encephalitozoon cuniculi)	4 / 7	LEU A 52 TYR A 49 HIS A 51 THR A 109	None	1.39A	1afsB-3mpdA: undetectable	1afsB-3mpdA: 17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GCS_A_BAXA401_2 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3mpd	NUCLEOSIDE DIPHOSPHATE KINASE (Encephalitozoon cuniculi)	4 / 6	MET A 73 MET A 65 ILE A 22 ILE A 114	None	0.86A	3gcsA-3mpdA: undetectable	3gcsA-3mpdA: 17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BLV_A_SAMA1281_1 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	3mpd	NUCLEOSIDE DIPHOSPHATE KINASE (Encephalitozoon cuniculi)	4 / 6	HIS A 51 HIS A 115 GLU A 121 ASP A 118	None	1.15A	4blvA-3mpdA: undetectable	4blvA-3mpdA: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YCN_A_8LXA501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3mpd	NUCLEOSIDE DIPHOSPHATE KINASE (Encephalitozoon cuniculi)	4 / 6	CYH A 119 SER A 117 HIS A 48 HIS A 51	None	1.50A	5ycnA-3mpdA: undetectable	5ycnA-3mpdA: 19.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AFS_B_TESB325_1","3-ALPHA-HYDROXYSTEROID DEHYDROGENASE","3mpd","NUCLEOSIDE DIPHOSPHATE KINASE","Encephalitozoon cuniculi",4,"LEU A  52;TYR A  49;HIS A  51;THR A 109","None","1.39A","1afsB-3mpdA:undetectable","1afsB-3mpdA:17.18"],["3GCS_A_BAXA401_2","MITOGEN-ACTIVATED PROTEIN KINASE 14","3mpd","NUCLEOSIDE DIPHOSPHATE KINASE","Encephalitozoon cuniculi",4,"MET A  73;MET A  65;ILE A  22;ILE A 114","None","0.86A","3gcsA-3mpdA:undetectable","3gcsA-3mpdA:17.96"],["4BLV_A_SAMA1281_1","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","3mpd","NUCLEOSIDE DIPHOSPHATE KINASE","Encephalitozoon cuniculi",4,"HIS A  51;HIS A 115;GLU A 121;ASP A 118","None","1.15A","4blvA-3mpdA:undetectable","4blvA-3mpdA:19.79"],["5YCN_A_8LXA501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3mpd","NUCLEOSIDE DIPHOSPHATE KINASE","Encephalitozoon cuniculi",4,"CYH A 119;SER A 117;HIS A  48;HIS A  51","None","1.50A","5ycnA-3mpdA:undetectable","5ycnA-3mpdA:19.71"]]