SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mpo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY
(Lactobacillus
brevis) 		4 / 7 TYR A 185
PRO A 159
GLN A 160
GLU A 163
 None
 1.26A 3l2vA-3mpoA:
undetectable		 3l2vA-3mpoA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY
(Lactobacillus
brevis) 		5 / 11 THR A 216
LEU A 200
GLY A 198
THR A 225
ASP A   9
 None
 0.98A 3lxiB-3mpoA:
undetectable		 3lxiB-3mpoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY
(Lactobacillus
brevis) 		4 / 7 TYR A 185
PRO A 159
GLN A 160
GLU A 163
 None
 1.10A 3s3oA-3mpoA:
undetectable		 3s3oA-3mpoA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY
(Lactobacillus
brevis) 		5 / 12 THR A 216
LEU A 200
GLY A 198
THR A 225
ASP A   9
 None
 0.99A 4c9lA-3mpoA:
undetectable		 4c9lA-3mpoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY
(Lactobacillus
brevis) 		5 / 12 THR A 216
LEU A 200
GLY A 198
THR A 225
ASP A   9
 None
 0.97A 4c9lB-3mpoA:
undetectable		 4c9lB-3mpoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY
(Lactobacillus
brevis) 		4 / 8 THR A 216
LEU A 200
GLY A 198
THR A 225
 None
 0.87A 4c9nA-3mpoA:
undetectable		 4c9nA-3mpoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY
(Lactobacillus
brevis) 		5 / 12 THR A 216
LEU A 200
GLY A 198
THR A 225
ASP A   9
 None
 1.07A 4c9oA-3mpoA:
undetectable		 4c9oA-3mpoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY
(Lactobacillus
brevis) 		5 / 12 THR A 216
LEU A 200
GLY A 198
THR A 225
ASP A   9
 None
 1.06A 4c9oB-3mpoA:
undetectable		 4c9oB-3mpoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY
(Lactobacillus
brevis) 		4 / 7 ILE A   6
LEU A 232
ALA A 262
ILE A 263
 None
 0.83A 4y03A-3mpoA:
undetectable		 4y03A-3mpoA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY
(Lactobacillus
brevis) 		4 / 8 ALA A 230
GLY A 197
LEU A 200
ALA A   7
 None
 0.81A 6mdqA-3mpoA:
undetectable		 6mdqA-3mpoA:
15.16