SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 9 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 1.01A 1hpvA-3mq0A:
undetectable		 1hpvA-3mq0A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.93A 2f80A-3mq0A:
undetectable		 2f80A-3mq0A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.94A 2f80B-3mq0A:
undetectable		 2f80B-3mq0A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.96A 2f81B-3mq0A:
undetectable		 2f81B-3mq0A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		4 / 6 SER A 188
LEU A 184
ASP A 210
ASP A 211
 None
 1.24A 2j2pE-3mq0A:
undetectable
2j2pF-3mq0A:
undetectable		 2j2pE-3mq0A:
20.07
2j2pF-3mq0A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.99A 2pymA-3mq0A:
undetectable		 2pymA-3mq0A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 1.00A 2pynA-3mq0A:
undetectable		 2pynA-3mq0A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.95A 2q63B-3mq0A:
undetectable		 2q63B-3mq0A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.94A 2q64A-3mq0A:
undetectable		 2q64A-3mq0A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.93A 3d20B-3mq0A:
undetectable		 3d20B-3mq0A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		4 / 6 THR A 105
ILE A 225
SER A 265
LEU A 268
 None
 0.88A 3deuB-3mq0A:
5.3		 3deuB-3mq0A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.90A 3jvyA-3mq0A:
undetectable		 3jvyA-3mq0A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.93A 3lzsA-3mq0A:
undetectable		 3lzsA-3mq0A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.87A 3mwsA-3mq0A:
undetectable		 3mwsA-3mq0A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.94A 3nduC-3mq0A:
undetectable		 3nduC-3mq0A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.92A 3oxxA-3mq0A:
undetectable		 3oxxA-3mq0A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		4 / 6 SER A 166
LEU A 168
ASP A 167
LEU A 173
 None
 1.02A 4wozA-3mq0A:
undetectable
4wozB-3mq0A:
undetectable		 4wozA-3mq0A:
21.91
4wozB-3mq0A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 10 GLY A 222
GLY A 254
LEU A 257
LEU A 116
TYR A 119
 None
 1.34A 5hwkA-3mq0A:
undetectable		 5hwkA-3mq0A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 10 GLY A 222
GLY A 254
LEU A 257
LEU A 116
TYR A 119
 None
 1.34A 5hwkB-3mq0A:
undetectable		 5hwkB-3mq0A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		4 / 8 SER A 239
THR A 120
THR A 122
ARG A 215
 None
 1.00A 5jhdE-3mq0A:
undetectable
5jhdG-3mq0A:
undetectable		 5jhdE-3mq0A:
20.83
5jhdG-3mq0A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 240
GLY A 254
VAL A 121
PRO A 118
ILE A 238
 None
 0.93A 5t2zA-3mq0A:
undetectable		 5t2zA-3mq0A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 3mq0 TRANSCRIPTIONAL
REPRESSOR OF THE
BLCABC OPERON
(Agrobacterium
tumefaciens) 		3 / 3 ARG A 258
ARG A 226
ARG A 203
 None
 0.96A 5vcgA-3mq0A:
undetectable		 5vcgA-3mq0A:
19.76