SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 6 VAL A   8
VAL A  50
ILE A  60
ASN A 267
 None
 0.97A 1e06A-3mq9A:
undetectable		 1e06A-3mq9A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 THR A 237
GLU A 214
ASP A 209
 None
 0.72A 1nt2A-3mq9A:
undetectable		 1nt2A-3mq9A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA A 269
ALA A  77
ALA A  52
GLY A  56
GLY A  54
 None
 1.08A 2igtA-3mq9A:
undetectable		 2igtA-3mq9A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA A 269
ALA A  77
ALA A  52
GLY A  56
GLY A  54
 None
 1.09A 2igtB-3mq9A:
undetectable		 2igtB-3mq9A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA A 264
LEU A 280
PHE A 279
VAL A 293
GLY A  16
 None
 1.09A 2ve3A-3mq9A:
undetectable		 2ve3A-3mq9A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 6 LEU A 247
ILE A 226
ILE A 348
LEU A 192
 None
 0.96A 2xkwB-3mq9A:
undetectable		 2xkwB-3mq9A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ILE A 108
LEU A 262
ILE A  59
VAL A  23
LEU A  20
 None
 1.02A 3a51C-3mq9A:
undetectable		 3a51C-3mq9A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 6 PRO A 126
LEU A 147
ALA A 223
PRO A 125
 None
 1.31A 3gv1A-3mq9A:
undetectable
3gv1C-3mq9A:
undetectable		 3gv1A-3mq9A:
14.44
3gv1C-3mq9A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 6 LEU A 147
ALA A 223
PRO A 125
PRO A 126
 None
 1.29A 3gv1A-3mq9A:
undetectable
3gv1B-3mq9A:
undetectable		 3gv1A-3mq9A:
14.44
3gv1B-3mq9A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 11 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.21A 3mg0H-3mq9A:
undetectable
3mg0I-3mq9A:
undetectable		 3mg0H-3mq9A:
21.35
3mg0I-3mq9A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 9 ILE A 132
LEU A 198
LYS A 256
ILE A 226
GLY A 191
 None
 1.16A 3sj4X-3mq9A:
undetectable		 3sj4X-3mq9A:
10.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VFJ_A_ACTA410_0
(MALTOSE-BINDING
PERIPLASMIC PROTEIN,
C-TERMINAL FUSED BY
CYS-LYS-D-ALA-D-ALA)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 4 LYS A  15
ALA A  63
GLU A 111
LEU A 262
 None
 0.64A 3vfjA-3mq9A:
57.7		 3vfjA-3mq9A:
81.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 5 GLU A 308
ASP A 314
ASP A 287
ASN A 294
 None
 1.37A 3vywD-3mq9A:
undetectable		 3vywD-3mq9A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_J_SPMJ202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 7 MET A 336
TRP A 340
TYR A 171
GLU A 328
 None
 1.31A 4r87J-3mq9A:
undetectable
4r87L-3mq9A:
undetectable		 4r87J-3mq9A:
16.49
4r87L-3mq9A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 7 LEU A  76
GLY A 265
ALA A 264
SER A 263
 None
 0.89A 5f1aB-3mq9A:
undetectable		 5f1aB-3mq9A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.25A 5l66H-3mq9A:
undetectable
5l66I-3mq9A:
undetectable		 5l66H-3mq9A:
21.23
5l66I-3mq9A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.25A 5l66V-3mq9A:
undetectable
5l66W-3mq9A:
undetectable		 5l66V-3mq9A:
21.23
5l66W-3mq9A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3mq9 BONE MARROW STROMAL
ANTIGEN 2 FUSED TO
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 None
 0.80A 6b58A-3mq9A:
undetectable		 6b58A-3mq9A:
22.95