SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mqm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 3mqm PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L
(Homo
sapiens) 		4 / 6 SER A2453
TYR A2538
GLN A2548
ASP A2449
 None
 1.16A 2cl5B-3mqmA:
undetectable		 2cl5B-3mqmA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3mqm PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L
(Homo
sapiens) 		4 / 6 SER A2453
TYR A2538
GLN A2548
ASP A2449
 None
 1.17A 2zvjA-3mqmA:
undetectable		 2zvjA-3mqmA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3mqm PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L
(Homo
sapiens) 		4 / 4 LEU A2488
MET A2510
VAL A2513
ASN A2516
 None
 1.50A 5b8iB-3mqmA:
undetectable		 5b8iB-3mqmA:
22.01