SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mqo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2LH8_A_VIBA1_1 (MAJOR PRION PROTEIN)	3mqo	TRANSCRIPTIONAL REGULATOR, LUXR FAMILY (Burkholderia thailandensis)	4 / 6	PRO A 67 MET A 69 ASP A 78 ASP A 77	None	1.06A	2lh8A-3mqoA: undetectable	2lh8A-3mqoA: 16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V81_C_NVPC901_1 (HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT)	3mqo	TRANSCRIPTIONAL REGULATOR, LUXR FAMILY (Burkholderia thailandensis)	4 / 8	LEU A 51 VAL A 18 VAL A 93 LEU A 43	None	0.85A	3v81C-3mqoA: undetectable	3v81C-3mqoA: 9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO0_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	3mqo	TRANSCRIPTIONAL REGULATOR, LUXR FAMILY (Burkholderia thailandensis)	4 / 7	PHE A 58 MET A 81 ARG A 23 VAL A 50	None None IPA A 1 ( 3.8A) None	1.48A	5uo0A-3mqoA: undetectable 5uo0B-3mqoA: undetectable	5uo0A-3mqoA: 14.29 5uo0B-3mqoA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BPL_B_PA1B605_1 (LIPID A EXPORT ATP-BINDING/PERMEASE PROTEIN MSBA)	3mqo	TRANSCRIPTIONAL REGULATOR, LUXR FAMILY (Burkholderia thailandensis)	3 / 3	ARG A 79 ARG A 23 ARG A 60	IPA A 1 ( 4.9A) IPA A 1 ( 3.8A) None	1.10A	6bplA-3mqoA: undetectable 6bplB-3mqoA: undetectable	6bplA-3mqoA: 19.51 6bplB-3mqoA: 19.51

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2LH8_A_VIBA1_1","MAJOR PRION PROTEIN","3mqo","TRANSCRIPTIONAL REGULATOR, LUXR FAMILY","Burkholderia thailandensis",4,"PRO A  67;MET A  69;ASP A  78;ASP A  77","None","1.06A","2lh8A-3mqoA:undetectable","2lh8A-3mqoA:16.53"],["3V81_C_NVPC901_1","HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT","3mqo","TRANSCRIPTIONAL REGULATOR, LUXR FAMILY","Burkholderia thailandensis",4,"LEU A  51;VAL A  18;VAL A  93;LEU A  43","None","0.85A","3v81C-3mqoA:undetectable","3v81C-3mqoA:9.64"],["5UO0_B_H4BB802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","3mqo","TRANSCRIPTIONAL REGULATOR, LUXR FAMILY","Burkholderia thailandensis",4,"PHE A  58;MET A  81;ARG A  23;VAL A  50","None;None;IPA A   1 ( 3.8A);None","1.48A","5uo0A-3mqoA:undetectable;5uo0B-3mqoA:undetectable","5uo0A-3mqoA:14.29;5uo0B-3mqoA:14.29"],["6BPL_B_PA1B605_1","LIPID A EXPORT ATP-BINDING\/PERMEASE PROTEIN MSBA;LIPID A EXPORT ATP-BINDING\/PERMEASE PROTEIN MSBA","3mqo","TRANSCRIPTIONAL REGULATOR, LUXR FAMILY","Burkholderia thailandensis",3,"ARG A  79;ARG A  23;ARG A  60","IPA A   1 ( 4.9A);IPA A   1 ( 3.8A);None","1.10A","6bplA-3mqoA:undetectable;6bplB-3mqoA:undetectable","6bplA-3mqoA:19.51;6bplB-3mqoA:19.51"]]