SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		5 / 12 ILE A 100
THR A  79
GLY A  97
LEU A   9
LEU A  44
 None
 1.10A 1rjdC-3mqzA:
undetectable		 1rjdC-3mqzA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		5 / 12 LEU A   9
LEU A 191
ILE A 100
THR A  79
ILE A 198
 None
 1.20A 1tw4B-3mqzA:
undetectable		 1tw4B-3mqzA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		5 / 12 LEU A 105
LEU A  44
LEU A  83
THR A 200
PHE A 183
 None
None
None
GOL  A 218 (-2.6A)
GOL  A 218 (-3.3A)
 1.39A 2oaxA-3mqzA:
undetectable		 2oaxA-3mqzA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		5 / 12 LEU A 105
LEU A  44
LEU A  83
THR A 200
PHE A 183
 None
None
None
GOL  A 218 (-2.6A)
GOL  A 218 (-3.3A)
 1.27A 2oaxF-3mqzA:
undetectable		 2oaxF-3mqzA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		4 / 8 LEU A 143
PHE A 183
THR A 200
LEU A 204
 None
GOL  A 218 (-3.3A)
GOL  A 218 (-2.6A)
None
 0.70A 3uniB-3mqzA:
undetectable		 3uniB-3mqzA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		5 / 11 LEU A  44
ARG A  43
VAL A  65
LEU A  13
LEU A  48
 None
 1.31A 4or0B-3mqzA:
undetectable		 4or0B-3mqzA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		4 / 7 PHE A 187
ASP A 188
GLN A  10
ILE A 194
 None
 0.95A 4pcuA-3mqzA:
undetectable		 4pcuA-3mqzA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		4 / 5 LEU A 179
PHE A 133
LEU A 204
TRP A 162
 None
 1.21A 5m10A-3mqzA:
undetectable		 5m10A-3mqzA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		5 / 12 ALA A  94
GLY A  97
LEU A 204
LEU A 122
LEU A 179
 None
 1.22A 5nfjB-3mqzA:
undetectable		 5nfjB-3mqzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		5 / 6 THR A 189
ASP A 188
ARG A   8
LEU A   9
ASP A  11
 CL  A 215 ( 4.3A)
None
None
None
None
 1.38A 5tdzA-3mqzA:
undetectable		 5tdzA-3mqzA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054
(Leptospirillum
rubarum) 		4 / 6 ARG A 108
ARG A 184
ASP A 180
ASP A 152
 None
 1.17A 5zw4A-3mqzA:
undetectable		 5zw4A-3mqzA:
21.07