SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mr0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3mr0 SENSORY BOX
HISTIDINE
KINASE/RESPONSE
REGULATOR
(Burkholderia
thailandensis) 		3 / 3 TRP A  20
HIS A  72
MET A 112
 PG5  A 143 (-3.5A)
None
PG5  A 143 ( 4.9A)
 1.26A 1l5qB-3mr0A:
undetectable		 1l5qB-3mr0A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3mr0 SENSORY BOX
HISTIDINE
KINASE/RESPONSE
REGULATOR
(Burkholderia
thailandensis) 		3 / 3 LYS A  36
TYR A  30
PRO A  33
 None
 0.93A 2j9cC-3mr0A:
undetectable		 2j9cC-3mr0A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3mr0 SENSORY BOX
HISTIDINE
KINASE/RESPONSE
REGULATOR
(Burkholderia
thailandensis) 		4 / 5 ILE A  50
ARG A  88
MET A  39
THR A  87
 None
None
PG5  A 143 ( 4.5A)
None
 1.23A 3abkN-3mr0A:
undetectable
3abkW-3mr0A:
undetectable		 3abkN-3mr0A:
13.07
3abkW-3mr0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3mr0 SENSORY BOX
HISTIDINE
KINASE/RESPONSE
REGULATOR
(Burkholderia
thailandensis) 		4 / 6 PRO A  24
LEU A  69
ALA A 101
PRO A 109
 None
PG5  A 143 ( 4.9A)
None
None
 1.32A 3gv1A-3mr0A:
undetectable
3gv1C-3mr0A:
undetectable		 3gv1A-3mr0A:
21.02
3gv1C-3mr0A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3mr0 SENSORY BOX
HISTIDINE
KINASE/RESPONSE
REGULATOR
(Burkholderia
thailandensis) 		4 / 6 LEU A  69
ALA A 101
PRO A 109
PRO A  24
 PG5  A 143 ( 4.9A)
None
None
None
 1.32A 3gv1A-3mr0A:
undetectable
3gv1B-3mr0A:
undetectable		 3gv1A-3mr0A:
21.02
3gv1B-3mr0A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3mr0 SENSORY BOX
HISTIDINE
KINASE/RESPONSE
REGULATOR
(Burkholderia
thailandensis) 		4 / 8 SER A  16
SER A  32
GLU A  45
ASP A  43
 None
 0.93A 4qb9D-3mr0A:
undetectable		 4qb9D-3mr0A:
16.06