SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mse'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 3mse CALCIUM-DEPENDENT
PROTEIN KINASE,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 TYR B  39
HIS B  51
TYR B  45
GLY B  53
 None
 1.32A 1mxgA-3mseB:
undetectable		 1mxgA-3mseB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3mse CALCIUM-DEPENDENT
PROTEIN KINASE,
PUTATIVE
(Plasmodium
falciparum) 		4 / 6 ALA B  27
TYR B  12
ILE B  25
ILE B  23
 None
 1.05A 2dcfA-3mseB:
undetectable		 2dcfA-3mseB:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3mse CALCIUM-DEPENDENT
PROTEIN KINASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP B  82
LEU B  81
PHE B  44
ASP B  48
ASN B  52
 None
None
None
CA  B 183 (-3.1A)
CA  B 183 (-2.8A)
 1.46A 2x2iA-3mseB:
undetectable		 2x2iA-3mseB:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3mse CALCIUM-DEPENDENT
PROTEIN KINASE,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 ALA B  27
TYR B  12
ILE B  25
ILE B  23
 None
 1.07A 2zm7A-3mseB:
undetectable		 2zm7A-3mseB:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3mse CALCIUM-DEPENDENT
PROTEIN KINASE,
PUTATIVE
(Plasmodium
falciparum) 		4 / 8 ALA B  27
TYR B  12
ILE B  25
ILE B  23
 None
 1.03A 2zmaA-3mseB:
undetectable		 2zmaA-3mseB:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 3mse CALCIUM-DEPENDENT
PROTEIN KINASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 11 ILE B 116
ASP B 117
ILE B 124
PHE B 146
VAL B 150
 None
CA  B 180 (-3.3A)
None
None
None
 1.08A 4ac9B-3mseB:
undetectable
4ac9C-3mseB:
undetectable		 4ac9B-3mseB:
18.97
4ac9C-3mseB:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3mse CALCIUM-DEPENDENT
PROTEIN KINASE,
PUTATIVE
(Plasmodium
falciparum) 		3 / 3 LYS B 118
SER B 125
SER B 127
 None
CA  B 180 ( 4.3A)
None
 0.73A 6gbfA-3mseB:
undetectable		 6gbfA-3mseB:
14.35