SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3msp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 3msp MAJOR SPERM PROTEIN
(Ascaris
suum) 		5 / 12 ASN A  95
ILE A  41
GLY A  37
ALA A  36
THR A  34
 None
 0.93A 1r9oA-3mspA:
undetectable		 1r9oA-3mspA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3msp MAJOR SPERM PROTEIN
(Ascaris
suum) 		5 / 12 GLY A  42
TRP A  93
LEU A  69
GLU A  66
ILE A  31
 None
 0.96A 2oxtC-3mspA:
undetectable		 2oxtC-3mspA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3msp MAJOR SPERM PROTEIN
(Ascaris
suum) 		4 / 8 VAL A  18
CYH A  74
TYR A  29
ILE A 122
 None
 1.10A 4bqtC-3mspA:
undetectable
4bqtD-3mspA:
undetectable		 4bqtC-3mspA:
21.20
4bqtD-3mspA:
21.20