SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3msv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A 174
ARG A 181
ARG A  77
 None
 0.72A 1l7fA-3msvA:
undetectable		 1l7fA-3msvA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A 174
ARG A 181
ARG A  77
 None
 0.68A 1l7hA-3msvA:
undetectable		 1l7hA-3msvA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 238
LEU A 242
PHE A 249
THR A 199
VAL A 202
 None
 1.18A 1n5xA-3msvA:
undetectable		 1n5xA-3msvA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 238
LEU A 242
PHE A 249
THR A 199
VAL A 202
 None
 1.18A 1n5xB-3msvA:
2.3		 1n5xB-3msvA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		5 / 12 GLU A 295
ASP A 247
GLY A 246
PHE A 249
LEU A  32
 None
 1.33A 1nw3A-3msvA:
undetectable		 1nw3A-3msvA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		5 / 12 SER A 250
VAL A 180
TYR A 241
ASN A 203
VAL A 202
 None
 1.39A 1x70A-3msvA:
undetectable		 1x70A-3msvA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		5 / 12 SER A 250
VAL A 180
TYR A 241
ASN A 203
VAL A 202
 None
 1.39A 1x70B-3msvA:
undetectable		 1x70B-3msvA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		5 / 9 LEU A 213
ALA A 175
LEU A 125
GLU A 145
LEU A 183
 None
 1.47A 2azqA-3msvA:
1.5		 2azqA-3msvA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		5 / 11 GLY A 246
ILE A 206
ALA A 209
VAL A 257
ILE A 261
 None
 0.91A 2nnhA-3msvA:
undetectable		 2nnhA-3msvA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		3 / 3 LEU A 112
PRO A 113
ARG A 101
 None
 0.64A 2qd5A-3msvA:
undetectable		 2qd5A-3msvA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		4 / 8 ASP A 310
TYR A 297
LEU A 301
SER A 317
 None
 0.99A 3lm8A-3msvA:
undetectable
3lm8C-3msvA:
undetectable		 3lm8A-3msvA:
20.15
3lm8C-3msvA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		3 / 3 LEU A 112
PRO A 113
ARG A 101
 None
 0.68A 4klrB-3msvA:
undetectable		 4klrB-3msvA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		5 / 11 TYR A 120
VAL A 127
ALA A 126
SER A 121
SER A 122
 None
 1.14A 4mmaA-3msvA:
undetectable		 4mmaA-3msvA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE A  93
HIS A  97
ILE A  96
ASN A 142
 None
 1.25A 4o7gB-3msvA:
4.0		 4o7gB-3msvA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		4 / 5 LEU A  69
ALA A 123
LEU A  72
VAL A 127
 None
 1.20A 5cr1A-3msvA:
undetectable		 5cr1A-3msvA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3msv NUCLEAR IMPORT
ADAPTOR, NRO1
(Schizosaccharomy
ces
pombe) 		4 / 4 GLN A 218
THR A 221
LEU A 235
LEU A 264
 None
 1.27A 5m5kB-3msvA:
undetectable		 5m5kB-3msvA:
25.68