SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3msx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 3msx RHO
GTPASE-ACTIVATING
PROTEIN 20
(Homo
sapiens) 		5 / 9 GLY B 443
SER B 444
LEU B 518
SER B 448
ASP B 449
 None
 1.45A 2j2pB-3msxB:
undetectable
2j2pC-3msxB:
undetectable		 2j2pB-3msxB:
22.55
2j2pC-3msxB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 3msx RHO
GTPASE-ACTIVATING
PROTEIN 20
(Homo
sapiens) 		4 / 5 GLU B 529
SER B 525
PRO B 520
SER B 524
 None
 1.21A 4k17B-3msxB:
undetectable		 4k17B-3msxB:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3msx RHO
GTPASE-ACTIVATING
PROTEIN 20
(Homo
sapiens) 		5 / 12 ILE B 430
LEU B 414
LEU B 362
LEU B 387
MET B 383
 None
 0.92A 5nfjA-3msxB:
undetectable		 5nfjA-3msxB:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3msx RHO
GTPASE-ACTIVATING
PROTEIN 20
(Homo
sapiens) 		4 / 6 PRO B 392
THR B 394
ASN B 502
LYS B 395
 None
 0.93A 5xxiA-3msxB:
undetectable		 5xxiA-3msxB:
19.05