SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mt0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 216
ILE A 154
LEU A 271
VAL A 270
LEU A 264
 None
 0.99A 1r30B-3mt0A:
undetectable		 1r30B-3mt0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  91
LEU A   8
HIS A  34
ALA A  24
LEU A  50
 None
 1.20A 2a58A-3mt0A:
2.1
2a58B-3mt0A:
2.1		 2a58A-3mt0A:
20.07
2a58B-3mt0A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  91
LEU A   8
HIS A  34
ALA A  24
LEU A  50
 None
 1.20A 2a58B-3mt0A:
3.0
2a58C-3mt0A:
3.5		 2a58B-3mt0A:
20.07
2a58C-3mt0A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  91
LEU A   8
HIS A  34
ALA A  24
LEU A  50
 None
 1.20A 2a58D-3mt0A:
3.5
2a58E-3mt0A:
3.1		 2a58D-3mt0A:
20.07
2a58E-3mt0A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  24
LEU A  50
LEU A  53
LEU A  21
LEU A  37
 None
 1.05A 2ceoA-3mt0A:
undetectable		 2ceoA-3mt0A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 169
THR A 168
ILE A 172
HIS A 216
 None
 0.97A 2jfaB-3mt0A:
undetectable		 2jfaB-3mt0A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  89
ALA A  24
GLY A  29
VAL A  30
ILE A   7
 None
 0.80A 2o4lA-3mt0A:
undetectable		 2o4lA-3mt0A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 10 ALA A  24
LEU A  50
LEU A  53
LEU A  21
LEU A  37
 None
 1.00A 2riwA-3mt0A:
undetectable
2riwB-3mt0A:
undetectable		 2riwA-3mt0A:
20.50
2riwB-3mt0A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		4 / 8 GLU A 281
SER A 285
GLN A  83
VAL A 120
 None
 1.27A 3b9lA-3mt0A:
undetectable		 3b9lA-3mt0A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  89
ALA A  24
GLY A  29
VAL A  30
ILE A   7
 None
 0.77A 3cyxA-3mt0A:
undetectable		 3cyxA-3mt0A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  89
ALA A  24
GLY A  29
ILE A   4
ILE A   7
 None
None
None
CL  A 290 ( 4.7A)
None
 0.85A 3ebzA-3mt0A:
undetectable		 3ebzA-3mt0A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  89
ALA A  24
GLY A  29
VAL A  30
ILE A   7
 None
 0.84A 3nu5A-3mt0A:
undetectable		 3nu5A-3mt0A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 9 LEU A  89
ALA A  24
GLY A  29
VAL A  30
ILE A   7
 None
 0.90A 3oxvA-3mt0A:
undetectable		 3oxvA-3mt0A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 9 LEU A  89
ALA A  24
GLY A  29
VAL A  30
ILE A   7
 None
 0.87A 3oxvC-3mt0A:
undetectable		 3oxvC-3mt0A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  89
ALA A  24
GLY A  29
VAL A  30
ILE A   7
 None
 0.92A 3oxwB-3mt0A:
undetectable		 3oxwB-3mt0A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  89
ALA A  24
GLY A  29
VAL A  30
ILE A   7
 None
 0.81A 3oxwD-3mt0A:
undetectable		 3oxwD-3mt0A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  89
ALA A  24
GLY A  29
VAL A  30
ILE A   7
 None
 0.85A 3oxxA-3mt0A:
undetectable		 3oxxA-3mt0A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  89
ALA A  24
GLY A  29
VAL A  30
ILE A   7
 None
 0.97A 3oxxD-3mt0A:
undetectable		 3oxxD-3mt0A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  89
ALA A  24
GLY A  29
ILE A   4
ILE A   7
 None
None
None
CL  A 290 ( 4.7A)
None
 0.83A 3s53B-3mt0A:
undetectable		 3s53B-3mt0A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  89
ALA A  24
GLY A  29
ILE A   4
ILE A   7
 None
None
None
CL  A 290 ( 4.7A)
None
 0.82A 3s54A-3mt0A:
undetectable		 3s54A-3mt0A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  89
ALA A  24
GLY A  29
ILE A   4
ILE A   7
 None
None
None
CL  A 290 ( 4.7A)
None
 0.85A 3s54B-3mt0A:
undetectable		 3s54B-3mt0A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 10 ILE A 104
ALA A 103
ASP A 262
VAL A 268
LEU A 113
 None
 1.29A 4kq8A-3mt0A:
undetectable		 4kq8A-3mt0A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 163
ASP A 160
GLN A   2
ILE A 134
VAL A 237
 None
 1.14A 5dpdB-3mt0A:
4.4		 5dpdB-3mt0A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  89
ALA A  24
GLY A  29
ILE A   4
ILE A   7
 None
None
None
CL  A 290 ( 4.7A)
None
 0.86A 5e5jB-3mt0A:
undetectable		 5e5jB-3mt0A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 121
VAL A   9
ILE A  11
GLY A  18
ILE A  91
 None
 1.09A 5kqxB-3mt0A:
undetectable		 5kqxB-3mt0A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
SER A   6
VAL A   9
ILE A  90
CYH A  87
 None
 1.41A 5mlmA-3mt0A:
undetectable		 5mlmA-3mt0A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 3mt0 UNCHARACTERIZED
PROTEIN PA1789
(Pseudomonas
aeruginosa) 		4 / 6 ARG A  23
ALA A  20
THR A 123
ALA A 126
 CL  A 288 (-4.1A)
None
None
None
 0.82A 6ma6A-3mt0A:
undetectable		 6ma6A-3mt0A:
14.69